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IID00012  Myc proto-oncogene protein (Homo sapiens) P01106
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
439
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 55-68 Hetero dimer : O00499
 Evidence NMR 1mv0 A Reference
       Region 1mv0 A 55-68 order
Seq 260-267 Hetero dimer : IID00377Complex
 Evidence X-RAY 4y7r B Reference
       Region 4y7r B 260-267 order
Seq 320-328 Hetero trimer : IID50012Complex
 Evidence X-RAY 1ee4 C Reference
       Region 1ee4 C 320-328 order
 Evidence X-RAY 1ee4 D Reference
       Region 1ee4 D 320-322 disorder
       Region 1ee4 D 323-327 order
       Region 1ee4 D 328-328 disorder
 Evidence X-RAY 1ee4 E Reference
       Region 1ee4 E 320-328 order
 Evidence X-RAY 1ee4 F Reference
       Region 1ee4 F 320-322 disorder
       Region 1ee4 F 323-326 order
       Region 1ee4 F 327-328 disorder
Seq 350-439 Homo dimer :
 Evidence X-RAY 5i50 A Reference
       Region 5i50 A 350-439 order
 Evidence X-RAY 5i50 B Reference
       Region 5i50 B 350-439 order
 Evidence X-RAY 5i4z A Reference
       Region 5i4z A 350-365 disorder
       Region 5i4z A 366-439 order
 Evidence X-RAY 5i4z B Reference
       Region 5i4z B 350-365 disorder
       Region 5i4z B 366-439 order
Seq 353-434 Hetero dimer : P61244
 Evidence X-RAY 1nkp A Reference
       Region 1nkp A 353-434 order
 Evidence X-RAY 1nkp D Reference
       Region 1nkp D 353-434 order
Seq 406-434 Hetero dimer : IID50243Complex
 Evidence NMR 1a93 A Reference
       Region 1a93 A 406-434 order
 Evidence NMR 2a93 A Reference
       Region 2a93 A 406-434 order
       Region 2a93 A 433-434 high_rmsd
Seq 410-419 Hetero trimer : P01654
 Evidence X-RAY 2or9 P Reference
       Region 2or9 P 410-419 order
SeqProS possible 260-267 Hetero dimer : IID00377Complex
       Region 4y7r B 260-267 order
SeqProS possible 320-328 Nuclear Localization Signal (NLS). Hetero trimer : IID50012Complex
       Region 1ee4 C 320-328 order
       Region 1ee4 E 320-328 order
       Region 1ee4 D 323-327 order
       Region 1ee4 F 323-326 order
Seqphosphorylation
    6-6 Phosphoserine
    8-8 Phosphothreonine; by RAF; in vitro
    58-58 Phosphothreonine; by GSK3; alternate
    62-62 Phosphoserine; by DYRK2
    71-71 Phosphoserine
    161-161 Phosphoserine
    293-293 Phosphoserine
    329-329 Phosphoserine; by PIM2; in vitro
Seqacetylation
    143-143 N6-acetyllysine; by PCAF; alternate
    148-148 N6-acetyllysine; alternate
    157-157 N6-acetyllysine; by PCAF
    275-275 N6-acetyllysine; by PCAF
    317-317 N6-acetyllysine; by PCAF
    323-323 N6-acetyllysine; by PCAF
    371-371 N6-acetyllysine; by PCAF
 
Prediction
DICHOT
Disorder 1-105,141-352,435-439
Known Domain 353-434
Cryptic Domain 106-140
SCOPe RPS-Blast
     1nkpA1 353-437 1e-28 a.38.1.1 Mad protein
SCOP Hmmer
     1nkpA_ 353-435 5.1e-20 HLH, helix-loop-helix D...
Pfam RPS-Blast
     PF01056 12-345 3e-43 Myc amino-terminal region
     PF02344 408-438 4e-06 Myc leucine zipper domain
Pfam Hmmer
    PF01056 1-345 3.2e-138 Myc amino-terminal region
    PF00010 355-407 5.5e-18 Helix-loop-helix DNA-bindi...
    PF02344 408-438 2.2e-19 Myc leucine zipper domain