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IID00032  Cyclin-A2 (Homo sapiens) P20248
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
432
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 171-431
 Evidence X-RAY 4bcn D Reference
       Region 4bcn D 171-176 disorder
       Region 4bcn D 177-431 order
Seq 171-432 Hetero dimer : IID00034Complex
 Evidence X-RAY 4bcm B Reference
       Region 4bcm B 171-175 disorder
       Region 4bcm B 176-432 order
 Evidence X-RAY 4bcm D Reference
       Region 4bcm D 171-175 disorder
       Region 4bcm D 176-321 order
       Region 4bcm D 322-330 disorder
       Region 4bcm D 331-363 order
       Region 4bcm D 364-371 disorder
       Region 4bcm D 372-428 order
       Region 4bcm D 429-432 disorder
 Evidence X-RAY 4bcp B Reference
       Region 4bcp B 171-175 disorder
       Region 4bcp B 176-432 order
 Evidence X-RAY 4bcp D Reference
       Region 4bcp D 171-175 disorder
       Region 4bcp D 176-432 order
 Evidence X-RAY 2bkz B Reference
       Region 2bkz B 174-175 disorder
       Region 2bkz B 176-432 order
 Evidence X-RAY 2bkz D Reference
       Region 2bkz D 174-177 disorder
       Region 2bkz D 178-432 order
 Evidence X-RAY 2bpm B Reference
       Region 2bpm B 174-174 disorder
       Region 2bpm B 175-432 order
 Evidence X-RAY 2bpm D Reference
       Region 2bpm D 174-177 disorder
       Region 2bpm D 178-432 order
 Evidence X-RAY 2c4g B Reference
       Region 2c4g B 173-174 disorder
       Region 2c4g B 175-432 order
 Evidence X-RAY 2c4g D Reference
       Region 2c4g D 173-174 disorder
       Region 2c4g D 175-432 order
 Evidence X-RAY 2c5n B Reference
       Region 2c5n B 174-174 disorder
       Region 2c5n B 175-432 order
 Evidence X-RAY 2c5n D Reference
       Region 2c5n D 174-174 disorder
       Region 2c5n D 175-432 order
 Evidence X-RAY 2c5o B Reference
       Region 2c5o B 173-174 disorder
       Region 2c5o B 175-432 order
 Evidence X-RAY 2c5o D Reference
       Region 2c5o D 173-174 disorder
       Region 2c5o D 175-432 order
 Evidence X-RAY 2c5v B Reference
       Region 2c5v B 174-174 disorder
       Region 2c5v B 175-432 order
 Evidence X-RAY 2c5v D Reference
       Region 2c5v D 174-174 disorder
       Region 2c5v D 175-432 order
 Evidence X-RAY 2c5x B Reference
       Region 2c5x B 174-174 disorder
       Region 2c5x B 175-432 order
 Evidence X-RAY 2c5x D Reference
       Region 2c5x D 174-174 disorder
       Region 2c5x D 175-432 order
 Evidence X-RAY 2c6t B Reference
       Region 2c6t B 175-432 order
 Evidence X-RAY 2c6t D Reference
       Region 2c6t D 175-432 order
 Evidence X-RAY 5cyi B Reference
       Region 5cyi B 174-174 disorder
       Region 5cyi B 175-432 order
 Evidence X-RAY 5cyi D Reference
       Region 5cyi D 174-176 disorder
       Region 5cyi D 177-432 order
 Evidence X-RAY 1e9h B Reference
       Region 1e9h B 175-432 order
 Evidence X-RAY 1e9h D Reference
       Region 1e9h D 175-432 order
 Evidence X-RAY 3eid B Reference
       Region 3eid B 173-175 disorder
       Region 3eid B 176-432 order
 Evidence X-RAY 3eid D Reference
       Region 3eid D 173-177 disorder
       Region 3eid D 178-432 order
 Evidence X-RAY 3ej1 B Reference
       Region 3ej1 B 173-174 disorder
       Region 3ej1 B 175-432 order
 Evidence X-RAY 3ej1 D Reference
       Region 3ej1 D 173-175 disorder
       Region 3ej1 D 176-432 order
 Evidence X-RAY 3eoc B Reference
       Region 3eoc B 173-175 disorder
       Region 3eoc B 176-432 order
 Evidence X-RAY 3eoc D Reference
       Region 3eoc D 173-175 disorder
       Region 3eoc D 176-432 order
 Evidence X-RAY 4eoi B Reference
       Region 4eoi B 175-432 order
 Evidence X-RAY 4eoi D Reference
       Region 4eoi D 175-177 disorder
       Region 4eoi D 178-432 order
 Evidence X-RAY 4eoj B Reference
       Region 4eoj B 175-175 disorder
       Region 4eoj B 176-432 order
 Evidence X-RAY 4eoj D Reference
       Region 4eoj D 175-175 disorder
       Region 4eoj D 176-431 order
       Region 4eoj D 432-432 disorder
 Evidence X-RAY 4eok B Reference
       Region 4eok B 175-432 order
 Evidence X-RAY 4eok D Reference
       Region 4eok D 175-175 disorder
       Region 4eok D 176-431 order
       Region 4eok D 432-432 disorder
 Evidence X-RAY 4eol B Reference
       Region 4eol B 175-175 disorder
       Region 4eol B 176-432 order
 Evidence X-RAY 4eol D Reference
       Region 4eol D 175-175 disorder
       Region 4eol D 176-431 order
       Region 4eol D 432-432 disorder
 Evidence X-RAY 4eom B Reference
       Region 4eom B 175-175 disorder
       Region 4eom B 176-432 order
 Evidence X-RAY 4eom D Reference
       Region 4eom D 175-175 disorder
       Region 4eom D 176-429 order
       Region 4eom D 430-432 disorder
 Evidence X-RAY 4eon B Reference
       Region 4eon B 175-175 disorder
       Region 4eon B 176-432 order
 Evidence X-RAY 4eon D Reference
       Region 4eon D 175-431 order
       Region 4eon D 432-432 disorder
 Evidence X-RAY 4eoo B Reference
       Region 4eoo B 175-432 order
 Evidence X-RAY 4eoo D Reference
       Region 4eoo D 175-175 disorder
       Region 4eoo D 176-429 order
       Region 4eoo D 430-432 disorder
 Evidence X-RAY 4eop B Reference
       Region 4eop B 175-175 disorder
       Region 4eop B 176-432 order
 Evidence X-RAY 4eop D Reference
       Region 4eop D 175-429 order
       Region 4eop D 430-432 disorder
 Evidence X-RAY 4eoq B Reference
       Region 4eoq B 175-175 disorder
       Region 4eoq B 176-432 order
 Evidence X-RAY 4eoq D Reference
       Region 4eoq D 175-175 disorder
       Region 4eoq D 176-429 order
       Region 4eoq D 430-432 disorder
 Evidence X-RAY 4eor B Reference
       Region 4eor B 175-175 disorder
       Region 4eor B 176-432 order
 Evidence X-RAY 4eor D Reference
       Region 4eor D 175-429 order
       Region 4eor D 430-432 disorder
 Evidence X-RAY 4eos B Reference
       Region 4eos B 175-175 disorder
       Region 4eos B 176-432 order
 Evidence X-RAY 4eos D Reference
       Region 4eos D 175-429 order
       Region 4eos D 430-432 disorder
 Evidence X-RAY 3f5x B Reference
       Region 3f5x B 177-432 order
 Evidence X-RAY 3f5x D Reference
       Region 3f5x D 177-177 disorder
       Region 3f5x D 178-432 order
 Evidence X-RAY 1fin B Reference
       Region 1fin B 173-432 order
 Evidence X-RAY 1fin D Reference
       Region 1fin D 173-432 order
 Evidence X-RAY 1fvv B Reference
       Region 1fvv B 173-432 order
 Evidence X-RAY 1fvv D Reference
       Region 1fvv D 173-432 order
 Evidence X-RAY 4fx3 B Reference
       Region 4fx3 B 175-175 disorder
       Region 4fx3 B 176-432 order
 Evidence X-RAY 4fx3 D Reference
       Region 4fx3 D 175-432 order
 Evidence X-RAY 1h1p B Reference
       Region 1h1p B 175-432 order
 Evidence X-RAY 1h1p D Reference
       Region 1h1p D 175-432 order
 Evidence X-RAY 1h1q B Reference
       Region 1h1q B 175-432 order
 Evidence X-RAY 1h1q D Reference
       Region 1h1q D 175-432 order
 Evidence X-RAY 1h1r B Reference
       Region 1h1r B 175-432 order
 Evidence X-RAY 1h1r D Reference
       Region 1h1r D 175-432 order
 Evidence X-RAY 1h1s B Reference
       Region 1h1s B 175-432 order
 Evidence X-RAY 1h1s D Reference
       Region 1h1s D 175-432 order
 Evidence X-RAY 1h24 D Reference
       Region 1h24 D 174-174 disorder
       Region 1h24 D 175-432 order
 Evidence X-RAY 1h25 D Reference
       Region 1h25 D 174-174 disorder
       Region 1h25 D 175-432 order
 Evidence X-RAY 1h26 D Reference
       Region 1h26 D 174-174 disorder
       Region 1h26 D 175-432 order
 Evidence X-RAY 1h27 D Reference
       Region 1h27 D 174-174 disorder
       Region 1h27 D 175-432 order
 Evidence X-RAY 2i40 B Reference
       Region 2i40 B 173-174 disorder
       Region 2i40 B 175-431 order
       Region 2i40 B 432-432 disorder
 Evidence X-RAY 2i40 D Reference
       Region 2i40 D 173-177 disorder
       Region 2i40 D 178-432 order
 Evidence X-RAY 1ogu B Reference
       Region 1ogu B 174-177 disorder
       Region 1ogu B 178-282 order
       Region 1ogu B 283-284 disorder
       Region 1ogu B 285-432 order
 Evidence X-RAY 1ogu D Reference
       Region 1ogu D 174-177 disorder
       Region 1ogu D 178-432 order
 Evidence X-RAY 1oi9 B Reference
       Region 1oi9 B 174-174 disorder
       Region 1oi9 B 175-432 order
 Evidence X-RAY 1oi9 D Reference
       Region 1oi9 D 174-177 disorder
       Region 1oi9 D 178-430 order
       Region 1oi9 D 431-432 disorder
 Evidence X-RAY 1oiu B Reference
       Region 1oiu B 174-176 disorder
       Region 1oiu B 177-432 order
 Evidence X-RAY 1oiu D Reference
       Region 1oiu D 174-176 disorder
       Region 1oiu D 177-432 order
 Evidence X-RAY 1oiy B Reference
       Region 1oiy B 174-174 disorder
       Region 1oiy B 175-432 order
 Evidence X-RAY 1oiy D Reference
       Region 1oiy D 174-174 disorder
       Region 1oiy D 175-432 order
 Evidence X-RAY 1okw B Reference
       Region 1okw B 173-174 disorder
       Region 1okw B 175-432 order
 Evidence X-RAY 1okw D Reference
       Region 1okw D 173-174 disorder
       Region 1okw D 175-432 order
 Evidence X-RAY 1ol1 B Reference
       Region 1ol1 B 173-174 disorder
       Region 1ol1 B 175-432 order
 Evidence X-RAY 1ol1 D Reference
       Region 1ol1 D 173-174 disorder
       Region 1ol1 D 175-432 order
 Evidence X-RAY 1ol2 B Reference
       Region 1ol2 B 173-174 disorder
       Region 1ol2 B 175-432 order
 Evidence X-RAY 1ol2 D Reference
       Region 1ol2 D 173-174 disorder
       Region 1ol2 D 175-432 order
 Evidence X-RAY 1p5e B Reference
       Region 1p5e B 175-432 order
 Evidence X-RAY 1p5e D Reference
       Region 1p5e D 175-432 order
 Evidence X-RAY 1pkd B Reference
       Region 1pkd B 175-432 order
 Evidence X-RAY 1pkd D Reference
       Region 1pkd D 175-432 order
 Evidence X-RAY 2uue B Reference
       Region 2uue B 174-174 disorder
       Region 2uue B 175-432 order
 Evidence X-RAY 2uue D Reference
       Region 2uue D 174-174 disorder
       Region 2uue D 175-432 order
 Evidence X-RAY 2uzb B Reference
       Region 2uzb B 175-432 order
 Evidence X-RAY 2uzb D Reference
       Region 2uzb D 175-432 order
 Evidence X-RAY 2uzd B Reference
       Region 2uzd B 175-432 order
 Evidence X-RAY 2uzd D Reference
       Region 2uzd D 175-432 order
 Evidence X-RAY 2uze B Reference
       Region 2uze B 175-432 order
 Evidence X-RAY 2uze D Reference
       Region 2uze D 175-432 order
 Evidence X-RAY 2uzl B Reference
       Region 2uzl B 175-175 disorder
       Region 2uzl B 176-432 order
 Evidence X-RAY 2uzl D Reference
       Region 2uzl D 175-175 disorder
       Region 2uzl D 176-432 order
 Evidence X-RAY 1vyw B Reference
       Region 1vyw B 174-174 disorder
       Region 1vyw B 175-432 order
 Evidence X-RAY 1vyw D Reference
       Region 1vyw D 174-177 disorder
       Region 1vyw D 178-432 order
 Evidence X-RAY 2wev B Reference
       Region 2wev B 173-174 disorder
       Region 2wev B 175-432 order
 Evidence X-RAY 2wev D Reference
       Region 2wev D 173-174 disorder
       Region 2wev D 175-432 order
 Evidence X-RAY 2wfy B Reference
       Region 2wfy B 173-175 disorder
       Region 2wfy B 176-432 order
 Evidence X-RAY 2wfy D Reference
       Region 2wfy D 173-432 order
 Evidence X-RAY 2whb B Reference
       Region 2whb B 173-174 disorder
       Region 2whb B 175-432 order
 Evidence X-RAY 2whb D Reference
       Region 2whb D 173-174 disorder
       Region 2whb D 175-432 order
 Evidence X-RAY 2wih B Reference
       Region 2wih B 173-175 disorder
       Region 2wih B 176-432 order
 Evidence X-RAY 2wih D Reference
       Region 2wih D 173-175 disorder
       Region 2wih D 176-322 order
       Region 2wih D 323-323 disorder
       Region 2wih D 324-432 order
 Evidence X-RAY 2wip B Reference
       Region 2wip B 173-174 disorder
       Region 2wip B 175-432 order
 Evidence X-RAY 2wip D Reference
       Region 2wip D 173-177 disorder
       Region 2wip D 178-432 order
 Evidence X-RAY 2wma D Reference
       Region 2wma D 174-174 disorder
       Region 2wma D 175-432 order
 Evidence X-RAY 2wmb D Reference
       Region 2wmb D 174-174 disorder
       Region 2wmb D 175-432 order
 Evidence X-RAY 2wpa B Reference
       Region 2wpa B 173-174 disorder
       Region 2wpa B 175-432 order
 Evidence X-RAY 2wpa D Reference
       Region 2wpa D 173-178 disorder
       Region 2wpa D 179-432 order
 Evidence X-RAY 2wxv D Reference
       Region 2wxv D 173-175 disorder
       Region 2wxv D 176-432 order
 Evidence X-RAY 2wxv B Reference
       Region 2wxv B 173-175 disorder
       Region 2wxv B 176-432 order
 Evidence X-RAY 2x1n D Reference
       Region 2x1n D 172-174 disorder
       Region 2x1n D 175-432 order
 Evidence X-RAY 2x1n B Reference
       Region 2x1n B 172-174 disorder
       Region 2x1n B 175-432 order
Seq 171-432 Hetero tetramer : IID00034Complex
 Evidence X-RAY 1jst B Reference
       Region 1jst B 175-432 order
 Evidence X-RAY 1jst D Reference
       Region 1jst D 175-432 order
 Evidence X-RAY 2v22 B Reference
       Region 2v22 B 174-174 disorder
       Region 2v22 B 175-432 order
 Evidence X-RAY 2v22 D Reference
       Region 2v22 D 174-174 disorder
       Region 2v22 D 175-432 order
 Evidence X-RAY 4bck B Reference
       Region 4bck B 171-175 disorder
       Region 4bck B 176-432 order
 Evidence X-RAY 4bck D Reference
       Region 4bck D 171-177 disorder
       Region 4bck D 178-430 order
       Region 4bck D 431-432 disorder
 Evidence X-RAY 4cfm B Reference
       Region 4cfm B 175-432 order
 Evidence X-RAY 4cfm D Reference
       Region 4cfm D 175-432 order
 Evidence X-RAY 4cfu B Reference
       Region 4cfu B 172-432 order
 Evidence X-RAY 4cfu D Reference
       Region 4cfu D 173-432 order
 Evidence X-RAY 4cfv B Reference
       Region 4cfv B 172-432 order
 Evidence X-RAY 4cfv D Reference
       Region 4cfv D 172-432 order
 Evidence X-RAY 4cfw B Reference
       Region 4cfw B 175-432 order
 Evidence X-RAY 4cfw D Reference
       Region 4cfw D 175-175 disorder
       Region 4cfw D 176-432 order
 Evidence X-RAY 2cjm B Reference
       Region 2cjm B 175-175 disorder
       Region 2cjm B 176-432 order
 Evidence X-RAY 2cjm D Reference
       Region 2cjm D 175-175 disorder
       Region 2cjm D 176-432 order
 Evidence X-RAY 2iw6 B Reference
       Region 2iw6 B 174-175 disorder
       Region 2iw6 B 176-432 order
 Evidence X-RAY 2iw6 D Reference
       Region 2iw6 D 174-177 disorder
       Region 2iw6 D 178-432 order
 Evidence X-RAY 2iw8 B Reference
       Region 2iw8 B 174-175 disorder
       Region 2iw8 B 176-282 order
       Region 2iw8 B 283-284 disorder
       Region 2iw8 B 285-432 order
 Evidence X-RAY 2iw8 D Reference
       Region 2iw8 D 174-177 disorder
       Region 2iw8 D 178-432 order
 Evidence X-RAY 2iw9 B Reference
       Region 2iw9 B 174-175 disorder
       Region 2iw9 B 176-282 order
       Region 2iw9 B 283-284 disorder
       Region 2iw9 B 285-432 order
 Evidence X-RAY 2iw9 D Reference
       Region 2iw9 D 174-177 disorder
       Region 2iw9 D 178-432 order
 Evidence X-RAY 5lmk B Reference
       Region 5lmk B 175-432 order
 Evidence X-RAY 5lmk D Reference
       Region 5lmk D 175-175 disorder
       Region 5lmk D 176-432 order
 Evidence X-RAY 5nev B Reference
       Region 5nev B 174-174 disorder
       Region 5nev B 175-429 order
       Region 5nev B 430-432 disorder
 Evidence X-RAY 5nev D Reference
       Region 5nev D 174-174 disorder
       Region 5nev D 175-429 order
       Region 5nev D 430-432 disorder
Seq 171-432 Hetero tetramer : IID00034Complex
 Evidence X-RAY 4bcn B Reference
       Region 4bcn B 171-175 disorder
       Region 4bcn B 176-432 order
Seq 173-432 Hetero tetramer : IID00034Complex
 Evidence X-RAY 4cfx B Reference
       Region 4cfx B 173-432 order
 Evidence X-RAY 4cfx D Reference
       Region 4cfx D 173-432 order
 Evidence X-RAY 5if1 B Reference
       Region 5if1 B 174-175 disorder
       Region 5if1 B 176-432 order
 Evidence X-RAY 5if1 D Reference
       Region 5if1 D 174-175 disorder
       Region 5if1 D 176-432 order
Seq 173-432 Hetero trimer : IID00034Complex
 Evidence X-RAY 1okv D Reference
       Region 1okv D 173-432 order
Seq 173-432 Hetero hexamer : IID00034Complex
 Evidence X-RAY 1urc B Reference
       Region 1urc B 173-174 disorder
       Region 1urc B 175-432 order
 Evidence X-RAY 1urc D Reference
       Region 1urc D 173-174 disorder
       Region 1urc D 175-432 order
Seq 173-432 Hetero trimer : IID00034Complex,IID00049Complex
 Evidence X-RAY 1jsu B Reference
       Region 1jsu B 173-174 disorder
       Region 1jsu B 175-432 order
Seq 173-432 Hetero trimer : IID00034Complex,IID00099Complex
 Evidence X-RAY 2cch B Reference
       Region 2cch B 173-432 order
 Evidence X-RAY 2cch D Reference
       Region 2cch D 173-175 disorder
       Region 2cch D 176-431 order
       Region 2cch D 432-432 disorder
Seq 173-432 Hetero trimer : IID00034Complex
 Evidence X-RAY 1okv B Reference
       Region 1okv B 173-174 disorder
       Region 1okv B 175-432 order
Seq 174-432 Hetero hexamer : IID00034Complex
 Evidence X-RAY 1qmz B Reference
       Region 1qmz B 174-174 disorder
       Region 1qmz B 175-432 order
 Evidence X-RAY 1qmz D Reference
       Region 1qmz D 174-174 disorder
       Region 1qmz D 175-432 order
Seq 174-432 Hetero trimer : IID00034Complex
 Evidence X-RAY 2wma B Reference
       Region 2wma B 174-174 disorder
       Region 2wma B 175-432 order
Seq 174-432 Hetero trimer : IID00017Complex,IID00034Complex
 Evidence X-RAY 1h25 B Reference
       Region 1h25 B 174-174 disorder
       Region 1h25 B 175-432 order
Seq 174-432 Hetero trimer : IID00034Complex,IID00130Complex
 Evidence X-RAY 1h28 B Reference
       Region 1h28 B 174-174 disorder
       Region 1h28 B 175-432 order
 Evidence X-RAY 1h28 D Reference
       Region 1h28 D 174-174 disorder
       Region 1h28 D 175-432 order
Seq 174-432 Hetero trimer : IID00015Complex,IID00034Complex
 Evidence X-RAY 1h26 B Reference
       Region 1h26 B 174-174 disorder
       Region 1h26 B 175-432 order
Seq 174-432 Hetero trimer : IID00034Complex,IID00064Complex
 Evidence X-RAY 1h24 B Reference
       Region 1h24 B 174-174 disorder
       Region 1h24 B 175-432 order
Seq 174-432 Hetero trimer : IID00034Complex
 Evidence X-RAY 2wmb B Reference
       Region 2wmb B 174-174 disorder
       Region 2wmb B 175-432 order
Seq 174-432 Hetero trimer : IID00034Complex,IID00049Complex
 Evidence X-RAY 1h27 B Reference
       Region 1h27 B 174-174 disorder
       Region 1h27 B 175-432 order
Seq 175-432 Hetero trimer : IID00034Complex,IID00099Complex
 Evidence X-RAY 2cci B Reference
       Region 2cci B 175-432 order
 Evidence X-RAY 2cci D Reference
       Region 2cci D 175-432 order
Seq 175-432 Hetero trimer : IID00034Complex
 Evidence X-RAY 1gy3 D Reference
       Region 1gy3 D 175-432 order
Seq 175-432 Hetero trimer : IID00034Complex
 Evidence X-RAY 1gy3 B Reference
       Region 1gy3 B 175-432 order
Seq 175-432 Hetero tetramer : IID00034Complex
 Evidence X-RAY 4cfn B Reference
       Region 4cfn B 175-176 disorder
       Region 4cfn B 177-282 order
       Region 4cfn B 283-284 disorder
       Region 4cfn B 285-432 order
 Evidence X-RAY 4cfn D Reference
       Region 4cfn D 175-175 disorder
       Region 4cfn D 176-282 order
       Region 4cfn D 283-284 disorder
       Region 4cfn D 285-432 order
Seqphosphorylation
    5-5 Phosphoserine
    55-55 Phosphoserine
Seqacetylation
    1-1 N-acetylmethionine
 
Prediction
DICHOT
Disorder 1-172
Known Domain 173-432
SCOPe RPS-Blast
     2cchB1 181-308 4e-65 a.74.1.1 CDK5 activator 1 (NCK5a, p25)
     2cchB2 309-432 6e-41 a.74.1.1 CDK5 activator 1 (NCK5a, p25)
SCOP Hmmer
     2f2cA1 175-306 7e-53 a.74.1.1 CDK5 activator 1 ...
     1vinA2 309-430 4.7e-38 a.74.1.1 CDK5 activator ...
Pfam RPS-Blast
     PF16500 28-166 2e-44 N-terminal region of cyclin_...
     PF00134 181-243 2e-07 Cyclin, N-terminal domain
     PF02984 309-424 1e-09 Cyclin, C-terminal domain
Pfam Hmmer
    PF16500 28-166 8.1e-52 N-terminal region of cyclin...
    PF00134 181-306 1.8e-52 Cyclin, N-terminal domain
    PF02984 309-426 2.9e-30 Cyclin, C-terminal domain