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IID00049  Cyclin-dependent kinase inhibitor 1B (Homo sapiens) P46527
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
198
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-198 Hetero trimer : IID00034Complex
 Evidence X-RAY 5uq3 C Reference
       Region 5uq3 C 1-50 disorder
       Region 5uq3 C 51-96 order
       Region 5uq3 C 97-198 disorder
Seqdisorder 1-198
 Evidence CD Reference
       Region 1-198 disorder
Seq 23-106 Hetero trimer : IID00032Complex,IID00034Complex
 Evidence X-RAY 1jsu C Reference
       Region 1jsu C 23-24 disorder
       Region 1jsu C 25-93 order
       Region 1jsu C 94-106 disorder
Seq 25-35 Hetero trimer : IID00032Complex
 Evidence X-RAY 1h27 E Reference
       Region 1h27 E 25-29 disorder
       Region 1h27 E 30-35 order
Seq 181-190 Hetero tetramer : IID00309Complex,IID00321Complex
 Evidence X-RAY 2ast D Reference
       Region 2ast D 181-190 order
SeqProS verified 25-93 Hetero trimer : IID00032Complex,IID00034Complex
       Region 1jsu C 25-93 order
       Region 1-198 disorder
SeqProS verified 30-35 Hetero trimer : IID00032Complex
       Region 1h27 E 30-35 order
       Region 1-198 disorder
SeqProS verified 51-96 Hetero trimer : IID00034Complex
       Region 5uq3 C 51-96 order
       Region 1-198 disorder
SeqProS verified 181-190 Hetero tetramer : IID00309Complex,IID00321Complex
       Region 2ast D 181-190 order
       Region 1-198 disorder
Seqphosphorylation
    10-10 Phosphoserine; by UHMK1
    74-74 Phosphotyrosine; by SRC
    88-88 Phosphotyrosine; by ABL
    89-89 Phosphotyrosine
    157-157 Phosphothreonine; by CaMK1
    170-170 Phosphothreonine
    187-187 Phosphothreonine; by PKB/AKT1
    198-198 Phosphothreonine; by CaMK1
 
Prediction
DICHOT
Disorder 1-24,94-198
Known Domain 25-93
Pfam RPS-Blast
     PF02234 37-79 1e-10 Cyclin-dependent kinase inhib...
Pfam Hmmer
    PF02234 31-79 2.5e-26 Cyclin-dependent kinase inhi...