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IID00053  Signal transducer and activator of transcription 2 (Homo sapiens) P52630
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
851
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 786-838 Hetero dimer : IID50008Complex
 Evidence NMR 2ka4 B Reference
       Region 2ka4 B 786-838 order
       Region 2ka4 B 786-786 high_rmsd
       Region 2ka4 B 836-838 high_rmsd
Seqdisorder 786-838
 Evidence NMR Reference
       Region 786-838 disorder
SeqProS verified 786-838 Hetero dimer : IID50008Complex
       Region 2ka4 B 786-838 order
       Region 786-838 disorder
Seqphosphorylation
    283-283 Phosphoserine
    287-287 Phosphoserine
    294-294 Phosphothreonine
    690-690 Phosphotyrosine; by JAK
    753-753 Phosphoserine
    800-800 Phosphothreonine
 
Prediction
DICHOT
Disorder 1-1,123-140,686-782,839-851
Known Domain 2-122,141-685,783-838
SCOPe RPS-Blast
     1bgfA 1-123 1e-27 a.90.1.1 Transcription factor STAT-4 N-domain
     1bg1A1 138-316 3e-25 a.47.1.1 STAT homologue coiled coil domain
     1bg1A2 317-567 7e-62 b.2.5.5 STAT homologue
     1bg1A3 568-699 3e-34 d.93.1.1 Abl tyrosine kinase
SCOP Hmmer
     1bgfA_ 1-124 2.3e-35 a.90.1.1 Transcription fac...
     1bg1A1 139-316 5.8e-47 a.47.1.1 STAT homologue ...
     1bg1A2 317-567 4.9e-94 b.2.5.5 STAT homologue
     1bg1A3 568-686 1.6e-42 d.93.1.1 Abl tyrosine ki...
Pfam RPS-Blast
     PF02865 2-122 6e-30 STAT protein, protein interac...
     PF01017 143-307 1e-20 STAT protein, all-alpha dom...
     PF02864 331-456 2e-20 STAT protein, DNA binding d...
     PF12188 783-838 3e-22 Signal transducer and activ...
Pfam Hmmer
    PF02865 2-122 9.6e-35 STAT protein, protein intera...
    PF01017 142-308 3.9e-53 STAT protein, all-alpha do...
    PF02864 321-456 2.8e-32 STAT protein, DNA binding ...
    PF00017 577-648 1.4e-14 SH2 domain
    PF12188 783-838 1.7e-36 Signal transducer and acti...