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IID00079  Interferon regulatory factor 3 (Homo sapiens) Q14653
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
427
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-112 Hetero tetramer : IID00441Complex
 Evidence X-RAY 1t2k A Reference
       Region 1t2k A 1-2 disorder
       Region 1t2k A 3-112 order
 Evidence X-RAY 1t2k B Reference
       Region 1t2k B 1-3 disorder
       Region 1t2k B 4-111 order
       Region 1t2k B 112-112 disorder
Seq 1-113 Monomer :
 Evidence X-RAY 3qu6 A Reference
       Region 3qu6 A 1-4 disorder
       Region 3qu6 A 5-40 order
       Region 3qu6 A 41-48 disorder
       Region 3qu6 A 49-110 order
       Region 3qu6 A 111-113 disorder
 Evidence X-RAY 3qu6 B Reference
       Region 3qu6 B 1-4 disorder
       Region 3qu6 B 5-40 order
       Region 3qu6 B 41-48 disorder
       Region 3qu6 B 49-110 order
       Region 3qu6 B 111-113 disorder
 Evidence X-RAY 3qu6 C Reference
       Region 3qu6 C 1-4 disorder
       Region 3qu6 C 5-39 order
       Region 3qu6 C 40-48 disorder
       Region 3qu6 C 49-110 order
       Region 3qu6 C 111-113 disorder
Seq 1-113 Homo tetramer :
 Evidence X-RAY 2pi0 A Reference
       Region 2pi0 A 1-4 disorder
       Region 2pi0 A 5-43 order
       Region 2pi0 A 44-51 disorder
       Region 2pi0 A 52-110 order
       Region 2pi0 A 111-113 disorder
 Evidence X-RAY 2pi0 B Reference
       Region 2pi0 B 1-112 order
       Region 2pi0 B 113-113 disorder
 Evidence X-RAY 2pi0 C Reference
       Region 2pi0 C 1-3 disorder
       Region 2pi0 C 4-110 order
       Region 2pi0 C 111-113 disorder
 Evidence X-RAY 2pi0 D Reference
       Region 2pi0 D 1-2 disorder
       Region 2pi0 D 3-46 order
       Region 2pi0 D 47-51 disorder
       Region 2pi0 D 52-111 order
       Region 2pi0 D 112-113 disorder
Seq 1-123 Homo tetramer :
 Evidence X-RAY 2o6g E Reference
       Region 2o6g E 1-2 disorder
       Region 2o6g E 3-112 order
       Region 2o6g E 113-123 disorder
 Evidence X-RAY 2o6g F Reference
       Region 2o6g F 1-3 disorder
       Region 2o6g F 4-111 order
       Region 2o6g F 112-123 disorder
 Evidence X-RAY 2o6g G Reference
       Region 2o6g G 1-2 disorder
       Region 2o6g G 3-112 order
       Region 2o6g G 113-123 disorder
 Evidence X-RAY 2o6g H Reference
       Region 2o6g H 1-3 disorder
       Region 2o6g H 4-111 order
       Region 2o6g H 112-123 disorder
Seq 9-111 Hetero tetramer : IID00207Complex,IID00491Complex,P19838
 Evidence X-RAY 2o61 A Reference
       Region 2o61 A 9-111 order
Seq 173-427 Homo dimer :
 Evidence X-RAY 1qwt A Reference
       Region 1qwt A 173-188 disorder
       Region 1qwt A 189-427 order
 Evidence X-RAY 1qwt B Reference
       Region 1qwt B 173-188 disorder
       Region 1qwt B 189-427 order
Seq 175-427 Monomer :
 Evidence X-RAY 3a77 A Reference
       Region 3a77 A 189-229 order
       Region 3a77 A 230-236 disorder
       Region 3a77 A 237-427 order
 Evidence X-RAY 3a77 B Reference
       Region 3a77 B 189-232 order
       Region 3a77 B 233-236 disorder
       Region 3a77 B 237-426 order
       Region 3a77 B 427-427 disorder
 Evidence X-RAY 3a77 C Reference
       Region 3a77 C 189-231 order
       Region 3a77 C 232-236 disorder
       Region 3a77 C 237-426 order
       Region 3a77 C 427-427 disorder
 Evidence X-RAY 3a77 D Reference
       Region 3a77 D 189-189 disorder
       Region 3a77 D 190-230 order
       Region 3a77 D 231-237 disorder
       Region 3a77 D 238-426 order
       Region 3a77 D 427-427 disorder
 Evidence X-RAY 1j2f A Reference
       Region 1j2f A 175-189 disorder
       Region 1j2f A 190-230 order
       Region 1j2f A 231-237 disorder
       Region 1j2f A 238-422 order
       Region 1j2f A 423-427 disorder
 Evidence X-RAY 1j2f B Reference
       Region 1j2f B 175-188 disorder
       Region 1j2f B 189-233 order
       Region 1j2f B 234-236 disorder
       Region 1j2f B 237-422 order
       Region 1j2f B 423-427 disorder
Seq 189-398 Hetero tetramer : IID00092Complex
 Evidence X-RAY 5jem A Reference
       Region 5jem A 189-195 disorder
       Region 5jem A 196-398 order
 Evidence X-RAY 5jem B Reference
       Region 5jem B 189-195 disorder
       Region 5jem B 196-398 order
Seq 189-398 Hetero tetramer : IID00092Complex
 Evidence X-RAY 5jem E Reference
       Region 5jem E 189-195 disorder
       Region 5jem E 196-398 order
 Evidence X-RAY 5jem G Reference
       Region 5jem G 189-198 disorder
       Region 5jem G 199-398 order
Seq 189-427 Hetero dimer : Q7Z434
 Evidence X-RAY 5jek A Reference
       Region 5jek A 189-422 order
       Region 5jek A 423-427 disorder
 Evidence X-RAY 5jek B Reference
       Region 5jek B 189-422 order
       Region 5jek B 423-427 disorder
Seq 189-427 Hetero dimer : Q99FX5
 Evidence X-RAY 5jeo A Reference
       Region 5jeo A 189-422 order
       Region 5jeo A 423-427 disorder
 Evidence X-RAY 5jer A Reference
       Region 5jer A 189-422 order
       Region 5jer A 423-427 disorder
 Evidence X-RAY 5jer C Reference
       Region 5jer C 189-422 order
       Region 5jer C 423-427 disorder
 Evidence X-RAY 5jer E Reference
       Region 5jer E 189-422 order
       Region 5jer E 423-427 disorder
 Evidence X-RAY 5jer G Reference
       Region 5jer G 189-422 order
       Region 5jer G 423-427 disorder
Seq 189-427 Hetero trimer : Q86WV6
 Evidence X-RAY 5jej A Reference
       Region 5jej A 189-422 order
       Region 5jej A 423-427 disorder
 Evidence X-RAY 5jej B Reference
       Region 5jej B 189-421 order
       Region 5jej B 422-427 disorder
Seq 189-427 Hetero dimer : Q8IUC6
 Evidence X-RAY 5jel A Reference
       Region 5jel A 189-422 order
       Region 5jel A 423-427 disorder
Seq 196-386 Hetero dimer : IID00092Complex
 Evidence X-RAY 1zoq A Reference
       Region 1zoq A 196-386 order
 Evidence X-RAY 1zoq B Reference
       Region 1zoq B 196-386 order
Seqphosphorylation
    3-3 Phosphothreonine
    14-14 Phosphoserine
    75-75 Phosphothreonine
    97-97 Phosphoserine
    123-123 Phosphoserine
    180-180 Phosphothreonine
    188-188 Phosphoserine
    237-237 Phosphothreonine
    244-244 Phosphothreonine
    253-253 Phosphothreonine
    386-386 Phosphoserine; by TBK1
    396-396 Phosphoserine; by IKKE
    398-398 Phosphoserine
    404-404 Phosphothreonine
    427-427 Phosphoserine
 
Prediction
DICHOT
Disorder 1-8,112-188
Known Domain 9-111,189-427
SCOPe RPS-Blast
     2pi0B 1-112 1e-36 a.4.5.23 Interferon regulatory factor 1 (IRF-1)
     3a77A 189-427 1e-75 b.26.1.3 Interferon regulatory factor 3 (IRF3),...
SCOP Hmmer
     1t2kA_ 4-111 1.2e-40 a.4.5.23 Interferon regula...
     1qwtA_ 189-426 6.3e-87 b.26.1.3 Interferon regu...
Pfam RPS-Blast
     PF00605 7-109 2e-30 Interferon regulatory factor ...
     PF10401 202-374 2e-39 Interferon-regulatory facto...
Pfam Hmmer
    PF00605 7-109 1.1e-38 Interferon regulatory factor...
    PF10401 202-379 7.6e-56 Interferon-regulatory fact...