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IID00105  DNA polymerase kappa (Homo sapiens) Q9UBT6
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
870
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-528 Monomer :
 Evidence X-RAY 3in5 A Reference
       Region 3in5 A 19-24 disorder
       Region 3in5 A 25-224 order
       Region 3in5 A 225-280 disorder
       Region 3in5 A 281-518 order
       Region 3in5 A 519-526 disorder
 Evidence X-RAY 3in5 B Reference
       Region 3in5 B 19-21 disorder
       Region 3in5 B 22-223 order
       Region 3in5 B 224-283 disorder
       Region 3in5 B 284-518 order
       Region 3in5 B 519-526 disorder
 Evidence X-RAY 2oh2 A Reference
       Region 2oh2 A 19-32 disorder
       Region 2oh2 A 33-224 order
       Region 2oh2 A 225-281 disorder
       Region 2oh2 A 282-517 order
       Region 2oh2 A 518-526 disorder
 Evidence X-RAY 2oh2 B Reference
       Region 2oh2 B 19-20 disorder
       Region 2oh2 B 21-224 order
       Region 2oh2 B 225-281 disorder
       Region 2oh2 B 282-517 order
       Region 2oh2 B 518-526 disorder
 Evidence X-RAY 3pzp A Reference
       Region 3pzp A 19-24 disorder
       Region 3pzp A 25-224 order
       Region 3pzp A 225-280 disorder
       Region 3pzp A 281-520 order
       Region 3pzp A 521-528 disorder
 Evidence X-RAY 3pzp B Reference
       Region 3pzp B 19-224 order
       Region 3pzp B 225-281 disorder
       Region 3pzp B 282-518 order
       Region 3pzp B 519-528 disorder
 Evidence X-RAY 5t14 A Reference
       Region 5t14 A 1-30 disorder
       Region 5t14 A 31-224 order
       Region 5t14 A 225-281 disorder
       Region 5t14 A 282-518 order
       Region 5t14 A 519-527 disorder
 Evidence X-RAY 5t14 B Reference
       Region 5t14 B 1-30 disorder
       Region 5t14 B 31-224 order
       Region 5t14 B 225-281 disorder
       Region 5t14 B 282-518 order
       Region 5t14 B 519-527 disorder
 Evidence X-RAY 1t94 A Reference
       Region 1t94 A 68-70 disorder
       Region 1t94 A 71-225 order
       Region 1t94 A 226-228 disorder
       Region 1t94 A 229-253 order
       Region 1t94 A 254-275 disorder
       Region 1t94 A 276-407 order
       Region 1t94 A 408-410 disorder
       Region 1t94 A 411-411 order
       Region 1t94 A 412-413 disorder
       Region 1t94 A 414-447 order
       Region 1t94 A 448-450 disorder
       Region 1t94 A 451-472 order
       Region 1t94 A 473-473 disorder
       Region 1t94 A 474-480 order
       Region 1t94 A 481-482 disorder
       Region 1t94 A 483-515 order
       Region 1t94 A 516-526 disorder
 Evidence X-RAY 1t94 B Reference
       Region 1t94 B 68-74 disorder
       Region 1t94 B 75-224 order
       Region 1t94 B 225-280 disorder
       Region 1t94 B 281-409 order
       Region 1t94 B 410-412 disorder
       Region 1t94 B 413-473 order
       Region 1t94 B 474-475 disorder
       Region 1t94 B 476-517 order
       Region 1t94 B 518-526 disorder
 Evidence X-RAY 4u6p A Reference
       Region 4u6p A 1-30 disorder
       Region 4u6p A 31-224 order
       Region 4u6p A 225-281 disorder
       Region 4u6p A 282-518 order
       Region 4u6p A 519-526 disorder
 Evidence X-RAY 4u6p B Reference
       Region 4u6p B 1-30 disorder
       Region 4u6p B 31-224 order
       Region 4u6p B 225-281 disorder
       Region 4u6p B 282-518 order
       Region 4u6p B 519-526 disorder
 Evidence X-RAY 4u7c A Reference
       Region 4u7c A 27-31 disorder
       Region 4u7c A 32-224 order
       Region 4u7c A 225-280 disorder
       Region 4u7c A 281-518 order
 Evidence X-RAY 4u7c B Reference
       Region 4u7c B 27-30 disorder
       Region 4u7c B 31-224 order
       Region 4u7c B 225-281 disorder
       Region 4u7c B 282-517 order
       Region 4u7c B 518-518 disorder
 Evidence X-RAY 5w2a A Reference
       Region 5w2a A 1-30 disorder
       Region 5w2a A 31-224 order
       Region 5w2a A 225-281 disorder
       Region 5w2a A 282-518 order
       Region 5w2a A 519-526 disorder
 Evidence X-RAY 5w2a B Reference
       Region 5w2a B 1-30 disorder
       Region 5w2a B 31-224 order
       Region 5w2a B 225-281 disorder
       Region 5w2a B 282-518 order
       Region 5w2a B 519-526 disorder
 Evidence X-RAY 5w2c A Reference
       Region 5w2c A 1-30 disorder
       Region 5w2c A 31-224 order
       Region 5w2c A 225-281 disorder
       Region 5w2c A 282-518 order
       Region 5w2c A 519-526 disorder
 Evidence X-RAY 5w2c B Reference
       Region 5w2c B 1-30 disorder
       Region 5w2c B 31-224 order
       Region 5w2c B 225-281 disorder
       Region 5w2c B 282-518 order
       Region 5w2c B 519-526 disorder
 Evidence X-RAY 2w7o B Reference
       Region 2w7o B 19-32 disorder
       Region 2w7o B 33-223 order
       Region 2w7o B 224-281 disorder
       Region 2w7o B 282-519 order
       Region 2w7o B 520-526 disorder
 Evidence X-RAY 2w7o A Reference
       Region 2w7o A 19-32 disorder
       Region 2w7o A 33-224 order
       Region 2w7o A 225-280 disorder
       Region 2w7o A 281-519 order
       Region 2w7o A 520-526 disorder
 Evidence X-RAY 2w7p A Reference
       Region 2w7p A 19-32 disorder
       Region 2w7p A 33-224 order
       Region 2w7p A 225-281 disorder
       Region 2w7p A 282-520 order
       Region 2w7p A 521-526 disorder
 Evidence X-RAY 2w7p B Reference
       Region 2w7p B 19-32 disorder
       Region 2w7p B 33-223 order
       Region 2w7p B 224-281 disorder
       Region 2w7p B 282-520 order
       Region 2w7p B 521-526 disorder
Seqdisorder 21-74
 Evidence Truncated Reference
       Region 21-74 disorder
Seq 562-577 Hetero dimer : IID00284Complex
 Evidence NMR 2lsi B Reference
       Region 2lsi B 562-577 order
       Region 2lsi B 562-563 high_rmsd
Seq 563-575 Hetero octamer : IID00284Complex
 Evidence X-RAY 4ba9 A Reference
       Region 4ba9 A 563-575 order
 Evidence X-RAY 4ba9 B Reference
       Region 4ba9 B 563-575 order
 Evidence X-RAY 4ba9 C Reference
       Region 4ba9 C 563-575 order
 Evidence X-RAY 4ba9 D Reference
       Region 4ba9 D 563-575 order
Seq 563-575 Hetero octamer : IID00284Complex
 Evidence X-RAY 4ba9 E Reference
       Region 4ba9 E 563-575 order
 Evidence X-RAY 4ba9 F Reference
       Region 4ba9 F 563-575 order
Seq 564-573 Hetero tetramer : IID00284Complex
 Evidence X-RAY 4gk5 G Reference
       Region 4gk5 G 564-565 disorder
       Region 4gk5 G 566-573 order
SeqProS verified 21-224 This region is described to adopt alpha-helical conformation only upon binding the Rev1-CT domain (PubMed=22691049). :
       Region 2oh2 B 21-224 order
       Region 5w2c A 31-224 order
       Region 5w2c B 31-224 order
       Region 5w2a A 31-224 order
       Region 5w2a B 31-224 order
       Region 5t14 A 31-224 order
       Region 5t14 B 31-224 order
       Region 21-74 disorder
SeqProS possible 562-577 This region is described to adopt alpha-helical conformation only upon binding the Rev1-CT domain (PubMed=22691049). Hetero dimer : IID00284Complex
       Region 2lsi B 562-577 order
SeqProS possible 566-573 This region is described to adopt alpha-helical conformation only upon binding the Rev1-CT domain (PubMed=22691049). Hetero tetramer : IID00284Complex
       Region 4gk5 G 566-573 order
 
Prediction
DICHOT
Disorder 1-9,48-70,516-870
Known Domain 71-515
Cryptic Domain 10-47
SCOPe RPS-Blast
     1t94A2 75-407 e-118 e.8.1.7 DinB homolog (DBH)
     1t94A1 411-515 1e-36 d.240.1.1 DinB homolog (DBH)
SCOP Hmmer
     1t94A2 76-406 2e-114 e.8.1.7 DinB homolog (DBH)
     1t94A1 412-514 1.1e-28 d.240.1.1 DinB homolog (...
Pfam RPS-Blast
     PF00817 106-151 4e-06 impB/mucB/samB family
     PF11798 340-370 5e-06 IMS family HHH motif
     PF11799 412-516 3e-08 impB/mucB/samB family C-ter...
Pfam Hmmer
    PF00817 106-324 6.2e-48 impB/mucB/samB family
    PF11798 340-370 2.4e-10 IMS family HHH motif
    PF11799 411-526 6.4e-20 impB/mucB/samB family C-te...