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IID00118  E3 ubiquitin-protein ligase RNF8 (Homo sapiens) O76064
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
485
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 8-139 Monomer :
 Evidence NMR 2csw A Reference
       Region 2csw A 8-139 order
       Region 2csw A 8-12 high_rmsd
Seq 13-146 Hetero dimer :
 Evidence X-RAY 2pie A Reference
       Region 2pie A 13-140 order
       Region 2pie A 141-146 disorder
Seq 345-485 Hetero tetramer : P61088
 Evidence X-RAY 4orh K Reference
       Region 4orh K 345-483 order
       Region 4orh K 484-485 disorder
 Evidence X-RAY 4orh L Reference
       Region 4orh L 345-483 order
       Region 4orh L 484-485 disorder
 Evidence X-RAY 4orh G Reference
       Region 4orh G 345-483 order
       Region 4orh G 484-485 disorder
 Evidence X-RAY 4orh H Reference
       Region 4orh H 345-483 order
       Region 4orh H 484-485 disorder
Seq 345-485 Hetero hexamer : P0CG47,P61088
 Evidence X-RAY 4whv C Reference
       Region 4whv C 345-480 order
       Region 4whv C 481-485 disorder
 Evidence X-RAY 4whv D Reference
       Region 4whv D 345-480 order
       Region 4whv D 481-485 disorder
 Evidence X-RAY 4whv I Reference
       Region 4whv I 345-379 disorder
       Region 4whv I 380-480 order
       Region 4whv I 481-485 disorder
 Evidence X-RAY 4whv J Reference
       Region 4whv J 345-379 disorder
       Region 4whv J 380-480 order
       Region 4whv J 481-485 disorder
Seq 345-485 Hetero trimer : P61088
 Evidence X-RAY 4orh C Reference
       Region 4orh C 345-391 disorder
       Region 4orh C 392-483 order
       Region 4orh C 484-485 disorder
Seq 351-485 Homo tetramer :
 Evidence X-RAY 4ayc A Reference
       Region 4ayc A 351-483 order
       Region 4ayc A 484-485 disorder
 Evidence X-RAY 4ayc B Reference
       Region 4ayc B 351-358 disorder
       Region 4ayc B 359-485 order
Seqphosphorylation
    157-157 Phosphoserine
 
Prediction
DICHOT
Disorder 1-12,141-350,484-485
Known Domain 13-140,351-483
SCOPe RPS-Blast
     2pieA2 13-140 1e-47 b.26.1.2 Afadin
     2y43A 397-466 2e-15 g.44.1.0 automated matches
SCOP Hmmer
     2cswA1 10-135 5.6e-29 b.26.1.2 Afadin
     1v87A_ 390-447 7.7e-20 RING/U-box
Pfam RPS-Blast
     PF16697 24-109 6e-09 Inner membrane component of ...
     PF12128 190-396 1e-05 Protein of unknown function...
     PF13923 402-440 6e-11 Zinc finger, C3HC4 type (RI...
Pfam Hmmer
    PF00498 38-109 8.8e-17 FHA domain
    PF13920 400-446 4.1e-13 Zinc finger, C3HC4 type (R...