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IID00119  Heterogeneous nuclear ribonucleoprotein A1 (Homo sapiens) P09651
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
372
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-196 Monomer :
 Evidence X-RAY 1ha1 A Reference
       Region 1ha1 A 1-8 disorder
       Region 1ha1 A 9-93 order
       Region 1ha1 A 94-99 disorder
       Region 1ha1 A 100-181 order
       Region 1ha1 A 182-184 disorder
 Evidence X-RAY 1l3k A Reference
       Region 1l3k A 1-7 disorder
       Region 1l3k A 8-91 order
       Region 1l3k A 92-102 disorder
       Region 1l3k A 103-181 order
       Region 1l3k A 182-196 disorder
 Evidence NMR 2lyv A Reference
       Region 2lyv A 2-196 order
       Region 2lyv A 2-4 high_rmsd
       Region 2lyv A 187-196 high_rmsd
 Evidence X-RAY 1pgz A Reference
       Region 1pgz A 2-7 disorder
       Region 1pgz A 8-190 order
       Region 1pgz A 191-196 disorder
 Evidence X-RAY 1po6 A Reference
       Region 1po6 A 8-190 order
 Evidence X-RAY 1u1k A Reference
       Region 1u1k A 1-7 disorder
       Region 1u1k A 8-190 order
       Region 1u1k A 191-196 disorder
 Evidence X-RAY 1u1l A Reference
       Region 1u1l A 1-7 disorder
       Region 1u1l A 8-190 order
       Region 1u1l A 191-196 disorder
 Evidence X-RAY 1u1m A Reference
       Region 1u1m A 1-7 disorder
       Region 1u1m A 8-190 order
       Region 1u1m A 191-196 disorder
 Evidence X-RAY 1u1n A Reference
       Region 1u1n A 1-7 disorder
       Region 1u1n A 8-190 order
       Region 1u1n A 191-196 disorder
 Evidence X-RAY 1u1o A Reference
       Region 1u1o A 1-7 disorder
       Region 1u1o A 8-190 order
       Region 1u1o A 191-196 disorder
 Evidence X-RAY 1u1p A Reference
       Region 1u1p A 1-7 disorder
       Region 1u1p A 8-190 order
       Region 1u1p A 191-196 disorder
 Evidence X-RAY 1u1q A Reference
       Region 1u1q A 1-7 disorder
       Region 1u1q A 8-190 order
       Region 1u1q A 191-196 disorder
 Evidence X-RAY 1u1r A Reference
       Region 1u1r A 1-7 disorder
       Region 1u1r A 8-190 order
       Region 1u1r A 191-196 disorder
 Evidence X-RAY 1up1 A Reference
       Region 1up1 A 3-6 disorder
       Region 1up1 A 7-92 order
       Region 1up1 A 93-98 disorder
       Region 1up1 A 99-182 order
       Region 1up1 A 183-184 disorder
 Evidence X-RAY 2up1 A Reference
       Region 2up1 A 8-190 order
 Evidence X-RAY 4yoe A Reference
       Region 4yoe A 1-7 disorder
       Region 4yoe A 8-188 order
       Region 4yoe A 189-196 disorder
Seq 2-97 Monomer :
 Evidence NMR 5mpg A Reference
       Region 5mpg A 2-97 order
       Region 5mpg A 2-7 high_rmsd
       Region 5mpg A 97-97 high_rmsd
Seq 95-196 Monomer :
 Evidence NMR 5mpl A Reference
       Region 5mpl A 95-196 order
       Region 5mpl A 95-96 high_rmsd
       Region 5mpl A 192-196 high_rmsd
Seq 309-357 Hetero hexamer : IID00094Complex
 Evidence X-RAY 2h4m C Reference
       Region 2h4m C 309-318 disorder
       Region 2h4m C 319-341 order
       Region 2h4m C 342-357 disorder
 Evidence X-RAY 2h4m D Reference
       Region 2h4m D 309-314 disorder
       Region 2h4m D 315-341 order
       Region 2h4m D 342-357 disorder
SeqProS verified 182-190 This region is ordered in the complex with ssDNA. :
       Region 2up1 A 8-190 order
       Region 1po6 A 8-190 order
       Region 1l3k A 182-196 disorder
SeqProS possible 315-341 Nuclear Localization Signal (NLS) Hetero hexamer : IID00094Complex
       Region 2h4m D 315-341 order
       Region 2h4m C 319-341 order
Seqphosphorylation
    2-2 Phosphoserine
    4-4 Phosphoserine
    6-6 Phosphoserine
    22-22 Phosphoserine
    192-192 Phosphoserine; by MKNK2
    199-199 Phosphoserine
    337-337 Phosphoserine
    361-361 Phosphoserine
    362-362 Phosphoserine; by MKNK2
    363-363 Phosphoserine; by MKNK2
    364-364 Phosphoserine; by MKNK2
    365-365 Phosphoserine
    368-368 Phosphoserine
Seqacetylation
    1-1 N-acetylmethionine
    2-2 N-acetylserine; in Heterogeneous nuclear ribonucleoprotein A1
    3-3 N6-acetyllysine; alternate
    350-350 N6-acetyllysine; alternate
 
Prediction
DICHOT
Disorder 1-8,182-372
Known Domain 9-181
SCOPe RPS-Blast
     1l3kA1 8-91 2e-48 d.58.7.1 Alkylation repair AlkB homolog 8, ALKBH8
     1l3kA2 103-181 2e-43 d.58.7.1 Alkylation repair AlkB homolog 8, ALKB...
     3ckcA 201-333 2e-05 a.118.8.6 Starch utilization system protein Sus...
SCOP Hmmer
     1u1qA_ 10-114 5.7e-33 RNA-binding domain, RBD
     1h2tZ_ 100-212 1.6e-29 d.58.7.1 Alkylation repa...
Pfam RPS-Blast
     PF16367 106-163 1e-05 RNA recognition motif
     PF05918 183-235 8e-05 Apoptosis inhibitory protei...
     PF03515 266-331 6e-04 Colicin-like bacteriocin tR...
Pfam Hmmer
    PF00076 16-82 2.2e-21 RNA recognition motif. (a.k....
    PF00076 107-167 8.5e-20 RNA recognition motif. (a....
    PF11627 307-344 6.8e-23 Nuclear factor hnRNPA1