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IID00126  DNA-directed RNA polymerase II subunit RPB1 (Homo sapiens) P24928
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1970
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 1593-1960
 Evidence CD¸ NMR Reference
       Region 1593-1960 disorder
Seq 1713-1740 Hetero tetramer : H6QM92
 Evidence X-RAY 5m3h X Reference
       Region 5m3h X 1713-1718 order
       Region 5m3h X 1719-1740 disorder
 Evidence X-RAY 5m3h Y Reference
       Region 5m3h Y 1713-1717 disorder
       Region 5m3h Y 1718-1727 order
       Region 5m3h Y 1728-1740 disorder
Seq 1713-1740 Hetero tetramer : Q5V8Z9
 Evidence X-RAY 5m3j X Reference
       Region 5m3j X 1713-1718 disorder
       Region 5m3j X 1719-1727 order
       Region 5m3j X 1728-1740 disorder
Seq 1787-1805 Hetero dimer : Q96P16
 Evidence X-RAY 4jxt B Reference
       Region 4jxt B 1787-1787 disorder
       Region 4jxt B 1788-1798 order
       Region 4jxt B 1799-1805 disorder
Seq 1790-1803 Hetero dimer : IID00590Complex
 Evidence X-RAY 3d9k Z Reference
       Region 3d9k Z 1790-1798 order
       Region 3d9k Z 1799-1803 disorder
 Evidence X-RAY 3d9k Y Reference
       Region 3d9k Y 1790-1794 disorder
       Region 3d9k Y 1795-1801 order
       Region 3d9k Y 1802-1803 disorder
 Evidence X-RAY 3d9l Y Reference
       Region 3d9l Y 1790-1799 order
       Region 3d9l Y 1800-1803 disorder
 Evidence X-RAY 3d9l Z Reference
       Region 3d9l Z 1790-1794 disorder
       Region 3d9l Z 1795-1802 order
       Region 3d9l Z 1803-1803 disorder
 Evidence X-RAY 3d9m Z Reference
       Region 3d9m Z 1790-1794 disorder
       Region 3d9m Z 1795-1803 order
 Evidence X-RAY 3d9m Y Reference
       Region 3d9m Y 1790-1792 order
       Region 3d9m Y 1793-1803 disorder
 Evidence X-RAY 3d9n Y Reference
       Region 3d9n Y 1790-1794 disorder
       Region 3d9n Y 1795-1803 order
 Evidence X-RAY 3d9n Z Reference
       Region 3d9n Z 1790-1794 disorder
       Region 3d9n Z 1795-1803 order
 Evidence X-RAY 3d9p Z Reference
       Region 3d9p Z 1790-1794 disorder
       Region 3d9p Z 1795-1802 order
       Region 3d9p Z 1803-1803 disorder
 Evidence X-RAY 3d9p Y Reference
       Region 3d9p Y 1790-1792 order
       Region 3d9p Y 1793-1803 disorder
Seq 1790-1803 Hetero trimer : IID00590Complex
 Evidence X-RAY 3d9o Z Reference
       Region 3d9o Z 1790-1794 disorder
       Region 3d9o Z 1795-1803 order
Seq 1795-1803 Hetero dimer : IID00394Complex
 Evidence X-RAY 2ghq C Reference
       Region 2ghq C 1795-1797 disorder
       Region 2ghq C 1798-1802 order
       Region 2ghq C 1803-1803 disorder
 Evidence X-RAY 2ghq D Reference
       Region 2ghq D 1795-1803 order
 Evidence X-RAY 2ght C Reference
       Region 2ght C 1796-1797 disorder
       Region 2ght C 1798-1802 order
       Region 2ght C 1803-1803 disorder
 Evidence X-RAY 2ght D Reference
       Region 2ght D 1796-1803 order
Seq 1804-1816 Hetero dimer : IID00499Complex
 Evidence NMR 2lto B Reference
       Region 2lto B 1804-1816 order
SeqProS verified 1713-1718 Hetero tetramer : Q5V8Z9
       Region 5m3j X 1719-1727 order
       Region 1593-1960 disorder
SeqProS verified 1719-1727 Hetero tetramer : H6QM92
       Region 5m3h X 1713-1718 order
       Region 5m3h Y 1718-1727 order
       Region 1593-1960 disorder
SeqProS verified 1788-1798 Hetero dimer : Q96P16
       Region 4jxt B 1788-1798 order
       Region 1593-1960 disorder
SeqProS verified 1790-1803 Hetero dimer : IID00590Complex
       Region 3d9n Y 1795-1803 order
       Region 3d9n Z 1795-1803 order
       Region 3d9k Y 1795-1801 order
       Region 3d9k Z 1790-1798 order
       Region 3d9p Y 1790-1792 order
       Region 3d9p Z 1795-1802 order
       Region 3d9l Y 1790-1799 order
       Region 3d9l Z 1795-1802 order
       Region 3d9m Y 1790-1792 order
       Region 3d9m Z 1795-1803 order
       Region 1593-1960 disorder
SeqProS verified 1795-1803 Hetero dimer : IID00394Complex
       Region 2ghq C 1798-1802 order
       Region 2ghq D 1795-1803 order
       Region 2ght C 1798-1802 order
       Region 2ght D 1796-1803 order
       Region 1593-1960 disorder
SeqProS verified 1795-1803 Hetero trimer : IID00590Complex
       Region 3d9o Z 1795-1803 order
       Region 1593-1960 disorder
SeqProS verified 1804-1816 Hetero dimer : IID00499Complex
       Region 2lto B 1804-1816 order
       Region 1593-1960 disorder
Seqphosphorylation
    27-27 Phosphoserine
    217-217 Phosphoserine
    1840-1840 Phosphothreonine
    1843-1843 Phosphoserine
    1845-1845 Phosphoserine
    1847-1847 Phosphoserine
    1849-1849 Phosphoserine
    1850-1850 Phosphoserine
    1854-1854 Phosphothreonine
    1857-1857 Phosphoserine
    1860-1860 Phosphotyrosine
    1861-1861 Phosphoserine
    1863-1863 Phosphothreonine
    1864-1864 Phosphoserine
    1867-1867 Phosphotyrosine
    1868-1868 Phosphoserine
    1870-1870 Phosphothreonine
    1874-1874 Phosphotyrosine
    1875-1875 Phosphoserine
    1877-1877 Phosphothreonine
    1878-1878 Phosphoserine
    1881-1881 Phosphotyrosine
    1882-1882 Phosphoserine
    1885-1885 Phosphothreonine
    1894-1894 Phosphothreonine
    1896-1896 Phosphoserine
    1899-1899 Phosphoserine
    1906-1906 Phosphoserine
    1909-1909 Phosphotyrosine
    1912-1912 Phosphothreonine
    1913-1913 Phosphoserine
    1915-1915 Phosphothreonine
    1916-1916 Phosphotyrosine
    1917-1917 Phosphoserine
    1919-1919 Phosphothreonine
    1920-1920 Phosphoserine
    1923-1923 Phosphotyrosine
    1926-1926 Phosphothreonine
    1927-1927 Phosphoserine
    1929-1929 Phosphothreonine
    1930-1930 Phosphotyrosine
    1931-1931 Phosphoserine
    1933-1933 Phosphothreonine
    1934-1934 Phosphoserine
Seqacetylation
    1-1 N-acetylmethionine
    1866-1866 N6-acetyllysine; alternate
    1887-1887 N6-acetyllysine; alternate
    1922-1922 N6-acetyllysine; alternate
    1936-1936 N6-acetyllysine; alternate
 
Prediction
DICHOT
Disorder 1-10,1516-1970
Known Domain 11-1515
SCOPe RPS-Blast
     1twfA 11-1479 0.0 e.29.1.2 RBP1
     1s58A 1580-1931 3e-04 b.121.5.2 Dependovirus capsid protein
SCOP Hmmer
     1i50A_ 13-1478 0 e.29.1.2 RBP1
Pfam RPS-Blast
     PF04997 17-354 3e-28 RNA polymerase Rpb1, domain ...
     PF00623 356-520 6e-25 RNA polymerase Rpb1, domain...
     PF04983 525-691 2e-15 RNA polymerase Rpb1, domain...
     PF04992 896-1079 2e-53 RNA polymerase Rpb1, domai...
     PF04990 1164-1299 2e-47 RNA polymerase Rpb1, doma...
     PF03154 1577-1969 2e-26 Atrophin-1 family
Pfam Hmmer
    PF04997 16-354 3.5e-112 RNA polymerase Rpb1, domai...
    PF00623 356-521 1.4e-77 RNA polymerase Rpb1, domai...
    PF04983 525-691 7.7e-53 RNA polymerase Rpb1, domai...
    PF05000 718-823 3.9e-41 RNA polymerase Rpb1, domai...
    PF04998 830-1425 4e-104 RNA polymerase Rpb1, domai...
    PF05001 1616-1629 0.00025 RNA polymerase Rpb1 C-te...
    PF05001 1630-1643 2.7e-05 RNA polymerase Rpb1 C-te...
    PF05001 1637-1650 0.00029 RNA polymerase Rpb1 C-te...
    PF05001 1644-1657 0.00028 RNA polymerase Rpb1 C-te...
    PF05001 1651-1664 0.0003 RNA polymerase Rpb1 C-ter...
    PF05001 1658-1671 0.00029 RNA polymerase Rpb1 C-te...
    PF05001 1665-1678 0.00031 RNA polymerase Rpb1 C-te...
    PF05001 1672-1685 0.00031 RNA polymerase Rpb1 C-te...
    PF05001 1679-1692 0.00032 RNA polymerase Rpb1 C-te...
    PF05001 1686-1699 0.00031 RNA polymerase Rpb1 C-te...
    PF05001 1693-1706 0.0003 RNA polymerase Rpb1 C-ter...
    PF05001 1700-1713 0.0003 RNA polymerase Rpb1 C-ter...
    PF05001 1707-1720 0.00032 RNA polymerase Rpb1 C-te...
    PF05001 1714-1727 0.0003 RNA polymerase Rpb1 C-ter...
    PF05001 1721-1734 0.00032 RNA polymerase Rpb1 C-te...
    PF05001 1728-1741 0.00031 RNA polymerase Rpb1 C-te...
    PF05001 1735-1748 7.5e-05 RNA polymerase Rpb1 C-te...
    PF05001 1742-1755 6.9e-06 RNA polymerase Rpb1 C-te...
    PF05001 1749-1762 7.5e-05 RNA polymerase Rpb1 C-te...
    PF05001 1770-1783 1.5e-05 RNA polymerase Rpb1 C-te...
    PF05001 1778-1790 7.6e-05 RNA polymerase Rpb1 C-te...
    PF05001 1791-1804 0.00032 RNA polymerase Rpb1 C-te...
    PF05001 1798-1811 0.00039 RNA polymerase Rpb1 C-te...
    PF05001 1805-1818 0.00083 RNA polymerase Rpb1 C-te...
    PF05001 1833-1846 0.00019 RNA polymerase Rpb1 C-te...
    PF05001 1847-1860 0.00012 RNA polymerase Rpb1 C-te...
    PF05001 1861-1874 1.3e-06 RNA polymerase Rpb1 C-te...
    PF05001 1868-1881 7.1e-06 RNA polymerase Rpb1 C-te...
    PF05001 1889-1902 0.00049 RNA polymerase Rpb1 C-te...
    PF05001 1896-1909 1.3e-05 RNA polymerase Rpb1 C-te...
    PF05001 1904-1916 2.2e-05 RNA polymerase Rpb1 C-te...
    PF05001 1917-1930 5.9e-06 RNA polymerase Rpb1 C-te...
    PF05001 1931-1947 0.00053 RNA polymerase Rpb1 C-te...
    PF05001 1941-1954 2.8e-06 RNA polymerase Rpb1 C-te...