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IID00151  E3 SUMO-protein ligase RanBP2 (Homo sapiens) P49792
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
3224
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-145 Monomer :
 Evidence X-RAY 4ga0 A Reference
       Region 4ga0 A 1-2 disorder
       Region 4ga0 A 3-145 order
Seq 1155-1321 Hetero dimer : IID00162Complex
 Evidence X-RAY 5cll B Reference
       Region 5cll B 1155-1168 disorder
       Region 5cll B 1169-1307 order
       Region 5cll B 1308-1321 disorder
 Evidence X-RAY 5cll D Reference
       Region 5cll D 1155-1168 disorder
       Region 5cll D 1169-1307 order
       Region 5cll D 1308-1321 disorder
 Evidence X-RAY 5clq B Reference
       Region 5clq B 1155-1172 disorder
       Region 5clq B 1173-1306 order
       Region 5clq B 1307-1321 disorder
 Evidence X-RAY 5clq D Reference
       Region 5clq D 1155-1175 disorder
       Region 5clq D 1176-1306 order
       Region 5clq D 1307-1321 disorder
 Evidence X-RAY 1rrp B Reference
       Region 1rrp B 1171-1304 order
 Evidence X-RAY 1rrp D Reference
       Region 1rrp D 1171-1304 order
Seqdisorder 1171-1190
 Evidence NMR Reference
       Region 1171-1190 disorder
Seqdisorder 1996-2027
 Evidence NMR Reference
       Region 1996-2027 disorder
Seq 2028-2154 Monomer :
 Evidence NMR 1xke A Reference
       Region 1xke A 2028-2154 order
       Region 1xke A 2028-2028 high_rmsd
       Region 1xke A 2152-2154 high_rmsd
Seq 2629-2695 Hetero tetramer : IID00376Complex,P63279
 Evidence X-RAY 3uin D Reference
       Region 3uin D 2629-2693 order
       Region 3uin D 2694-2695 disorder
 Evidence X-RAY 3uio D Reference
       Region 3uio D 2631-2694 order
       Region 3uio D 2695-2695 disorder
Seq 2631-2711 Hetero tetramer : IID00378Complex,P63279
 Evidence X-RAY 3uip D Reference
       Region 3uip D 2631-2690 order
       Region 3uip D 2691-2695 disorder
 Evidence X-RAY 1z5s D Reference
       Region 1z5s D 2631-2693 order
       Region 1z5s D 2694-2711 disorder
Seq 2705-2717 Hetero dimer : IID00378Complex
 Evidence NMR 2las B Reference
       Region 2las B 2705-2717 order
       Region 2las B 2705-2705 high_rmsd
Seq 2907-3050 Monomer :
 Evidence X-RAY 4l6e A Reference
       Region 4l6e A 2907-2924 disorder
       Region 4l6e A 2925-3048 order
       Region 4l6e A 3049-3050 disorder
Seq 3057-3224 Hetero dimer : P12497
 Evidence X-RAY 4lqw A Reference
       Region 4lqw A 3057-3224 order
 Evidence X-RAY 4lqw B Reference
       Region 4lqw B 3057-3224 order
Seq 3062-3224 Monomer :
 Evidence X-RAY 4i9y A Reference
       Region 4i9y A 3062-3224 order
 Evidence X-RAY 4i9y B Reference
       Region 4i9y B 3062-3224 order
 Evidence X-RAY 4i9y C Reference
       Region 4i9y C 3062-3224 order
 Evidence X-RAY 4i9y D Reference
       Region 4i9y D 3062-3224 order
 Evidence X-RAY 4i9y E Reference
       Region 4i9y E 3062-3224 order
 Evidence X-RAY 4i9y F Reference
       Region 4i9y F 3062-3224 order
SeqProS verified 1171-1190 Hetero dimer : IID00162Complex
       Region 1rrp B 1171-1304 order
       Region 1rrp D 1171-1304 order
       Region 1171-1190 disorder
Seqphosphorylation
    19-19 Phosphothreonine
    21-21 Phosphoserine
    779-779 Phosphothreonine
    781-781 Phosphoserine
    788-788 Phosphoserine
    837-837 Phosphoserine
    948-948 Phosphoserine
    955-955 Phosphoserine
    1098-1098 Phosphothreonine
    1103-1103 Phosphoserine
    1107-1107 Phosphoserine
    1110-1110 Phosphoserine
    1144-1144 Phosphothreonine
    1160-1160 Phosphoserine
    1249-1249 Phosphoserine
    1396-1396 Phosphothreonine
    1412-1412 Phosphothreonine
    1443-1443 Phosphoserine
    1450-1450 Phosphoserine
    1456-1456 Phosphoserine
    1509-1509 Phosphoserine
    1520-1520 Phosphoserine
    1573-1573 Phosphoserine
    1833-1833 Phosphoserine
    1835-1835 Phosphoserine
    1869-1869 Phosphoserine
    1871-1871 Phosphoserine
    2005-2005 Phosphothreonine
    2008-2008 Phosphoserine
    2153-2153 Phosphothreonine
    2246-2246 Phosphoserine
    2251-2251 Phosphoserine
    2270-2270 Phosphoserine
    2280-2280 Phosphoserine
    2290-2290 Phosphoserine
    2293-2293 Phosphothreonine
    2297-2297 Phosphoserine
    2462-2462 Phosphoserine
    2493-2493 Phosphoserine
    2510-2510 Phosphoserine
    2526-2526 Phosphoserine
    2613-2613 Phosphothreonine
    2666-2666 Phosphotyrosine
    2668-2668 Phosphoserine
    2741-2741 Phosphoserine
    2743-2743 Phosphothreonine
    2805-2805 Phosphoserine
    2900-2900 Phosphoserine
    3207-3207 Phosphoserine
Seqacetylation
    1977-1977 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-1,266-276,498-509,586-627,690-709,751-794,827-1170,1305-1353,1381-1414,1443-1469,1513-1533,1570-1596,1633-1655,1692-1714,1751-1772,1821-2026,2155-2323,2452-2631,2694-2931,3049-3061
Known Domain 2-145,1171-1304,1354-1380,1415-1442,1470-1512,1534-1569,1597-1632,1656-1691,1715-1750,1773-1820,2027-2154,2324-2451,2632-2693,2932-3048,3062-3224
Cryptic Domain 146-265,277-497,510-585,628-689,710-750,795-826
SCOPe RPS-Blast
     5o9zG 30-260 8e-15 a.118.8.1 Bro1
     4gmxB 1186-1306 3e-46 b.55.1.0 automated matches
     2ebvA1 1339-1380 9e-05 g.41.11.1 MDM2
     2ebvA1 1391-1442 1e-07 g.41.11.1 MDM2
     2ebvA1 1465-1506 1e-08 g.41.11.1 MDM2
     2ebvA1 1525-1572 5e-13 g.41.11.1 MDM2
     2ebvA1 1588-1632 7e-13 g.41.11.1 MDM2
     2ebvA1 1646-1691 2e-13 g.41.11.1 MDM2
     2ebvA1 1705-1750 2e-13 g.41.11.1 MDM2
     2ebvA1 1763-1809 4e-10 g.41.11.1 MDM2
     4gmxB 2027-2143 7e-45 b.55.1.0 automated matches
     4gmxB 2324-2445 2e-43 b.55.1.0 automated matches
     4gmxB 2925-3046 2e-43 b.55.1.0 automated matches
     2wfiA 3063-3224 2e-88 b.62.1.1 Cyclophilin (eukaryotic)
SCOP Hmmer
     2c2lA1 31-191 1.9e-16 a.118.8.1 Bro1
     1rrpB_ 1171-1303 3.3e-50 b.55.1.3 Nuclear pore ...
     2gqeA1 1354-1380 2.1e-05 g.41.11.1 MDM2
     2gqeA1 1415-1442 1.6e-08 g.41.11.1 MDM2
     2gqeA1 1479-1506 1.3e-08 g.41.11.1 MDM2
     2gqeA1 1543-1569 1.9e-08 g.41.11.1 MDM2
     2gqeA1 1606-1632 2.6e-09 g.41.11.1 MDM2
     2gqeA1 1665-1691 2.6e-09 g.41.11.1 MDM2
     2gqeA1 1724-1750 3.4e-08 g.41.11.1 MDM2
     2gqeA1 1782-1809 5.3e-08 g.41.11.1 MDM2
     1rrpB_ 2012-2143 2e-46 b.55.1.3 Nuclear pore co...
     1rrpB_ 2310-2440 1.2e-47 b.55.1.3 Nuclear pore ...
     1k5dB_ 2907-3045 1.1e-46 b.55.1.3 Nuclear pore ...
     1ihgA2 3057-3224 1.4e-67 b.62.1.1 Cyclophilin (...
Pfam RPS-Blast
     PF13429 24-132 4e-08 Tetratricopeptide repeat
     PF12851 761-1195 1e-08 Oxygenase domain of the 2O...
     PF00638 1184-1300 3e-20 RanBP1 domain
     PF00641 1416-1442 6e-05 Zn-finger in Ran binding ...
     PF00641 1480-1507 5e-07 Zn-finger in Ran binding ...
     PF00641 1544-1569 1e-06 Zn-finger in Ran binding ...
     PF00641 1607-1632 3e-07 Zn-finger in Ran binding ...
     PF00641 1666-1691 3e-07 Zn-finger in Ran binding ...
     PF00641 1725-1750 5e-07 Zn-finger in Ran binding ...
     PF00641 1782-1809 8e-07 Zn-finger in Ran binding ...
     PF00638 2027-2142 3e-18 RanBP1 domain
     PF00638 2322-2438 7e-18 RanBP1 domain
     PF12185 2631-2689 1e-14 Nup358/RanBP2 E3 ligase d...
     PF12185 2709-2765 1e-19 Nup358/RanBP2 E3 ligase d...
     PF00638 2923-3040 2e-19 RanBP1 domain
     PF00160 3077-3221 1e-04 Cyclophilin type peptidyl...
Pfam Hmmer
    PF00638 1183-1303 1.9e-59 RanBP1 domain
    PF00641 1351-1381 8.5e-11 Zn-finger in Ran binding...
    PF00641 1415-1443 2.5e-13 Zn-finger in Ran binding...
    PF00641 1479-1508 6.9e-15 Zn-finger in Ran binding...
    PF00641 1543-1571 1.2e-14 Zn-finger in Ran binding...
    PF00641 1606-1635 2e-15 Zn-finger in Ran binding p...
    PF00641 1665-1694 2e-15 Zn-finger in Ran binding p...
    PF00641 1724-1753 2.9e-13 Zn-finger in Ran binding...
    PF00641 1781-1809 6.1e-15 Zn-finger in Ran binding...
    PF00638 2024-2144 6.7e-59 RanBP1 domain
    PF00638 2321-2441 1.9e-58 RanBP1 domain
    PF12185 2631-2691 1.2e-27 Nup358/RanBP2 E3 ligase ...
    PF12185 2709-2768 9e-31 Nup358/RanBP2 E3 ligase do...
    PF00638 2922-3042 4.8e-61 RanBP1 domain
    PF00160 3077-3222 1.1e-43 Cyclophilin type peptidy...