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IID00153  Importin subunit alpha-1 (Homo sapiens) P52292
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
529
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 11-54 Hetero dimer : IID00386Complex
 Evidence X-RAY 1qgk B Reference
       Region 1qgk B 11-54 order
Seq 28-54 Hetero dimer : IID00386Complex
 Evidence X-RAY 1qgr B Reference
       Region 1qgr B 28-51 order
       Region 1qgr B 52-54 disorder
Seq 60-529 Hetero dimer : Q7Z7C8
 Evidence X-RAY 4wv6 A Reference
       Region 4wv6 A 60-71 disorder
       Region 4wv6 A 72-497 order
       Region 4wv6 A 498-529 disorder
Seq 70-497 Hetero trimer : Q9H7Z6
 Evidence X-RAY 5h43 A Reference
       Region 5h43 A 70-497 order
Seq 70-529 Hetero trimer : IID00167Complex
 Evidence X-RAY 3fex C Reference
       Region 3fex C 70-86 order
       Region 3fex C 87-88 disorder
       Region 3fex C 89-215 order
       Region 3fex C 216-218 disorder
       Region 3fex C 219-496 order
       Region 3fex C 497-529 disorder
Seq 70-529 Monomer :
 Evidence X-RAY 4e4v A Reference
       Region 4e4v A 70-497 order
       Region 4e4v A 498-529 disorder
 Evidence X-RAY 4e4v B Reference
       Region 4e4v B 70-497 order
       Region 4e4v B 498-529 disorder
 Evidence X-RAY 3wpt A Reference
       Region 3wpt A 75-496 order
       Region 3wpt A 497-497 disorder
 Evidence X-RAY 3wpt B Reference
       Region 3wpt B 75-497 order
Seq 70-529 Hetero trimer : IID00167Complex,IID00238Complex
 Evidence X-RAY 3fey C Reference
       Region 3fey C 70-215 order
       Region 3fey C 216-218 disorder
       Region 3fey C 219-499 order
       Region 3fey C 500-529 disorder
Seq 204-212 Hetero pentamer : IID00628Complex,P04222
 Evidence X-RAY 1efx C Reference
       Region 1efx C 204-212 order
SeqProS possible 11-54 Same region of mouse homolog (P52293, 96% identity) is disordered in the free state. (PubMed=11448961) Hetero dimer : IID00386Complex
       Region 1qgk B 11-54 order
SeqProS possible 28-51 Same region of mouse homolog (P52293, 96% identity) is disordered in the free state. (PubMed=11448961) Hetero dimer : IID00386Complex
       Region 1qgr B 28-51 order
Seqphosphorylation
    62-62 Phosphoserine
    490-490 Phosphoserine
Seqacetylation
    2-2 N-acetylserine
 
Prediction
DICHOT
Disorder 1-10,55-71,498-529
Known Domain 11-54,72-497
SCOPe RPS-Blast
     4b8jA 28-496 e-137 a.118.1.0 automated matches
SCOP Hmmer
     1wa5B_ 11-501 9.6e-126 a.118.1.1 beta-Catenin
Pfam RPS-Blast
     PF01749 15-91 1e-14 Importin beta binding domain
     PF04826 115-333 3e-10 Armadillo-like
     PF00514 325-362 1e-07 Armadillo/beta-catenin-like...
     PF00514 368-403 3e-06 Armadillo/beta-catenin-like...
     PF00514 411-447 5e-04 Armadillo/beta-catenin-like...
     PF16186 458-509 2e-19 Atypical Arm repeat
Pfam Hmmer
    PF01749 13-98 7.2e-33 Importin beta binding domain
    PF00514 109-149 1.2e-11 Armadillo/beta-catenin-lik...
    PF00514 151-190 8.6e-14 Armadillo/beta-catenin-lik...
    PF00514 194-238 5.2e-14 Armadillo/beta-catenin-lik...
    PF00514 249-279 8.1e-11 Armadillo/beta-catenin-lik...
    PF00514 283-321 2.1e-09 Armadillo/beta-catenin-lik...
    PF00514 324-364 1.1e-14 Armadillo/beta-catenin-lik...
    PF00514 367-405 2.2e-12 Armadillo/beta-catenin-lik...
    PF00514 410-447 3.3e-11 Armadillo/beta-catenin-lik...
    PF16186 458-509 3e-27 Atypical Arm repeat