Search Keyword:


Search option:


IID00155  Telomeric repeat-binding factor 1 (Homo sapiens) P54274
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
439
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-55 Hetero tetramer : IID50231Complex
 Evidence X-RAY 5hkp C Reference
       Region 5hkp C 1-10 disorder
       Region 5hkp C 11-22 order
       Region 5hkp C 23-55 disorder
 Evidence X-RAY 5hkp D Reference
       Region 5hkp D 1-10 disorder
       Region 5hkp D 11-21 order
       Region 5hkp D 22-55 disorder
Seq 58-268 Hetero tetramer : IID00180Complex
 Evidence X-RAY 3bqo A Reference
       Region 3bqo A 58-61 disorder
       Region 3bqo A 62-201 order
       Region 3bqo A 202-206 disorder
       Region 3bqo A 207-268 order
Seq 58-268 Hetero dimer : IID00630Complex
 Evidence X-RAY 3l82 A Reference
       Region 3l82 A 58-63 disorder
       Region 3l82 A 64-266 order
       Region 3l82 A 267-268 disorder
Seq 62-265 Homo dimer :
 Evidence X-RAY 1h6o A Reference
       Region 1h6o A 62-138 order
       Region 1h6o A 139-140 disorder
       Region 1h6o A 141-204 order
       Region 1h6o A 205-211 disorder
       Region 1h6o A 212-265 order
Seq 62-266 Hetero tetramer : Q8NA31
 Evidence X-RAY 5wir A Reference
       Region 5wir A 62-265 order
 Evidence X-RAY 5wir B Reference
       Region 5wir B 62-265 order
 Evidence X-RAY 5xup A Reference
       Region 5xup A 65-266 order
 Evidence X-RAY 5xup B Reference
       Region 5xup B 65-201 order
       Region 5xup B 202-206 disorder
       Region 5xup B 207-265 order
       Region 5xup B 266-266 disorder
Seq 371-439 Monomer :
 Evidence NMR 1ba5 A Reference
       Region 1ba5 A 378-430 order
       Region 1ba5 A 378-382 disorder
       Region 1ba5 A 378-381 high_rmsd
       Region 1ba5 A 383-430 order
       Region 1ba5 A 430-430 high_rmsd
 Evidence NMR 1ity A Reference
       Region 1ity A 371-372 disorder
       Region 1ity A 371-382 disorder
       Region 1ity A 373-439 order
       Region 1ity A 373-381 high_rmsd
       Region 1ity A 383-439 order
       Region 1ity A 434-439 high_rmsd
 Evidence NMR 1iv6 A Reference
       Region 1iv6 A 371-377 disorder
       Region 1iv6 A 378-434 order
       Region 1iv6 A 378-378 high_rmsd
       Region 1iv6 A 434-434 high_rmsd
       Region 1iv6 A 435-439 disorder
Seq 379-431 Homo dimer :
 Evidence X-RAY 1w0t A Reference
       Region 1w0t A 379-430 order
       Region 1w0t A 431-431 disorder
 Evidence X-RAY 1w0t B Reference
       Region 1w0t B 379-430 order
       Region 1w0t B 431-431 disorder
SeqProS predicted 11-21 The unbound state of this region is predicted to be disordered by DICHOT, Foldindex and MobiDB. Hetero tetramer : IID50231Complex
       Region 5hkp C 11-22 order
       Region 5hkp D 11-21 order
SeqProS verified 139-140 Hetero tetramer : IID00180Complex
       Region 3bqo A 62-201 order
       Region 1h6o A 139-140 disorder
SeqProS verified 139-140 Hetero tetramer : Q8NA31
       Region 5wir A 62-265 order
       Region 5wir B 62-265 order
       Region 5xup A 65-266 order
       Region 5xup B 65-201 order
       Region 1h6o A 139-140 disorder
SeqProS verified 378-382 This region binds upon DNA. :
       Region 1iv6 A 378-434 order
       Region 1ity A 371-382 disorder
Seqphosphorylation
    11-11 Phosphoserine
    219-219 Phosphoserine; by ATM
Seqacetylation
    2-2 N-acetylalanine
 
Prediction
DICHOT
Disorder 1-76,266-378,431-439
Known Domain 77-265,379-430
SCOPe RPS-Blast
     3bqoA 62-268 7e-67 a.146.1.1 TRF1
     3sjmA 379-432 4e-22 a.4.1.4 DNA-binding domain of human telomeric p...
SCOP Hmmer
     1h6oA_ 63-265 4.3e-89 a.146.1.1 TRF1
     2ckxA1 382-435 1.2e-16 a.4.1.3 2610100b20rik ge...
Pfam RPS-Blast
     PF08558 77-268 1e-54 Telomere repeat binding fact...
     PF00249 380-427 2e-05 Myb-like DNA-binding domain
Pfam Hmmer
    PF08558 77-269 4.1e-39 Telomere repeat binding fac...
    PF00249 380-427 3.7e-14 Myb-like DNA-binding domai...