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IID00189  Nuclear receptor corepressor 1 (Homo sapiens) O75376
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
2440
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 433-486 Monomer :
 Evidence NMR 2eqr A Reference
       Region 2eqr A 433-486 order
       Region 2eqr A 433-438 high_rmsd
       Region 2eqr A 484-486 high_rmsd
Seq 2045-2065 Hetero dimer : IID00033Complex
 Evidence X-RAY 3n00 B Reference
       Region 3n00 B 2045-2065 order
Seq 2045-2065 Hetero tetramer : IID00033Complex
 Evidence X-RAY 3n00 B Reference
       Region 3n00 B 2045-2065 order
Seq 2047-2065 Hetero tetramer : IID00365Complex
 Evidence X-RAY 3kmz C Reference
       Region 3kmz C 2047-2065 order
 Evidence X-RAY 3kmz D Reference
       Region 3kmz D 2047-2065 order
Seq 2258-2276 Hetero trimer : IID00014Complex
 Evidence X-RAY 3h52 N Reference
       Region 3h52 N 2258-2259 disorder
       Region 3h52 N 2260-2274 order
       Region 3h52 N 2275-2276 disorder
 Evidence X-RAY 3h52 M Reference
       Region 3h52 M 2258-2264 disorder
       Region 3h52 M 2265-2274 order
       Region 3h52 M 2275-2276 disorder
Seq 2259-2275 Hetero tetramer : IID00391Complex
 Evidence X-RAY 4wvd C Reference
       Region 4wvd C 2259-2259 disorder
       Region 4wvd C 2260-2275 order
 Evidence X-RAY 4wvd D Reference
       Region 4wvd D 2259-2275 order
Seq 2260-2274 Hetero tetramer : IID00014Complex
 Evidence X-RAY 4mdd C Reference
       Region 4mdd C 2260-2260 disorder
       Region 4mdd C 2261-2273 order
       Region 4mdd C 2274-2274 disorder
 Evidence X-RAY 4mdd D Reference
       Region 4mdd D 2260-2261 disorder
       Region 4mdd D 2262-2273 order
       Region 4mdd D 2274-2274 disorder
SeqProS possible 2045-2065 This region may be ProS because of similarity to other nuclear receptor co-repressors/co-acitivators. (e.g. IID00050, 74, 82, 83, 103) Hetero dimer : IID00033Complex
       Region 3n00 B 2045-2065 order
SeqProS possible 2045-2065 This region may be ProS because of similarity to other nuclear receptor co-repressors/co-acitivators. (e.g. IID00050, 74, 82, 83, 103) Hetero tetramer : IID00033Complex
       Region 3n00 B 2045-2065 order
SeqProS possible 2047-2065 This region may be ProS because of similarity to other nuclear receptor co-repressors/co-acitivators.(e.g. IID00050, 74, 82, 83, 103) Hetero tetramer : IID00365Complex
       Region 3kmz C 2047-2065 order
       Region 3kmz D 2047-2065 order
SeqProS possible 2259-2275 This region may be ProS because of similarity to other nuclear receptor co-repressors/co-acitivators.(e.g. IID00050, 74, 82, 83, 103) Hetero tetramer : IID00391Complex
       Region 4wvd C 2260-2275 order
       Region 4wvd D 2259-2275 order
SeqProS possible 2260-2274 This region may be ProS because of similarity to other nuclear receptor co-repressors/co-acitivators.(e.g. IID00050, 74, 82, 83, 103) Hetero trimer : IID00014Complex
       Region 3h52 M 2265-2274 order
       Region 3h52 N 2260-2274 order
SeqProS possible 2261-2273 This region may be ProS because of similarity to other nuclear receptor co-repressors/co-acitivators.(e.g. IID00050, 74, 82, 83, 103) Hetero tetramer : IID00014Complex
       Region 4mdd C 2261-2273 order
       Region 4mdd D 2262-2273 order
Seqphosphorylation
    172-172 Phosphoserine
    224-224 Phosphoserine
    999-999 Phosphoserine
    1111-1111 Phosphoserine
    1195-1195 Phosphoserine
    1196-1196 Phosphoserine
    1249-1249 Phosphoserine
    1263-1263 Phosphoserine
    1281-1281 Phosphoserine
    1322-1322 Phosphoserine
    1367-1367 Phosphothreonine
    1450-1450 Phosphoserine
    1472-1472 Phosphoserine
    1592-1592 Phosphoserine
    1977-1977 Phosphoserine
    1981-1981 Phosphoserine
    2102-2102 Phosphoserine
    2120-2120 Phosphoserine
    2136-2136 Phosphoserine
    2151-2151 Phosphoserine
    2184-2184 Phosphoserine
    2399-2399 Phosphothreonine
    2436-2436 Phosphoserine
    2438-2438 Phosphoserine
Seqacetylation
    1336-1336 N6-acetyllysine
    1412-1412 N6-acetyllysine; alternate
 
Prediction
DICHOT
Disorder 1-255,324-377,485-627,695-1540,1591-2440
Known Domain 416-484,628-694
Cryptic Domain 256-323,378-415,1541-1590
SCOPe RPS-Blast
     4a69C 416-484 3e-30 a.4.1.3 2610100b20rik gene product
     2ltpA 628-694 4e-24 a.4.1.0 automated matches
SCOP Hmmer
     1xc5A1 422-487 6.3e-18 a.4.1.3 2610100b20rik ge...
     1xc5A1 624-675 1.1e-15 a.4.1.3 2610100b20rik ge...
Pfam RPS-Blast
     PF15784 149-238 2e-20 G-protein pathway suppresso...
     PF05262 490-606 5e-05 Borrelia P83/100 protein
     PF00249 627-669 6e-07 Myb-like DNA-binding domain
Pfam Hmmer
    PF15784 150-238 3.4e-40 G-protein pathway suppress...
    PF00249 625-670 2.4e-16 Myb-like DNA-binding domai...