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IID00207  Transcription factor p65 (Homo sapiens) Q04206
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
551
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 20-291 Hetero tetramer : P19838
 Evidence X-RAY 3gut A Reference
       Region 3gut A 20-291 order
 Evidence X-RAY 3gut C Reference
       Region 3gut C 20-291 order
 Evidence X-RAY 3gut E Reference
       Region 3gut E 20-291 order
 Evidence X-RAY 3gut G Reference
       Region 3gut G 20-291 order
Seq 20-291 Hetero tetramer : IID00079Complex,IID00491Complex,P19838
 Evidence X-RAY 2o61 A Reference
       Region 2o61 A 20-291 order
Seq 20-320 Hetero trimer : IID00654Complex,P19838
 Evidence X-RAY 1nfi A Reference
       Region 1nfi A 20-314 order
       Region 1nfi A 315-320 disorder
 Evidence X-RAY 1nfi C Reference
       Region 1nfi C 20-320 order
Seq 302-316 Hetero dimer : Q8TBK2
 Evidence X-RAY 3rc0 P Reference
       Region 3rc0 P 302-306 disorder
       Region 3rc0 P 307-312 order
       Region 3rc0 P 313-316 disorder
Seq 302-316 Hetero dimer : Q8TBK2
 Evidence X-RAY 3qxy P Reference
       Region 3qxy P 302-302 disorder
       Region 3qxy P 303-303 order
       Region 3qxy P 304-316 disorder
 Evidence X-RAY 3qxy Q Reference
       Region 3qxy Q 302-302 disorder
       Region 3qxy Q 303-303 order
       Region 3qxy Q 304-316 disorder
 Evidence X-RAY 3rc0 Q Reference
       Region 3rc0 Q 302-302 disorder
       Region 3rc0 Q 303-303 order
       Region 3rc0 Q 304-316 disorder
Seq 304-316 Hetero dimer : IID00111Complex
 Evidence NMR 2lsp A Reference
       Region 2lsp A 304-316 order
Seq 308-314 Hetero dimer : IID00111Complex
 Evidence X-RAY 4kv1 C Reference
       Region 4kv1 C 308-314 order
 Evidence X-RAY 4kv1 D Reference
       Region 4kv1 D 308-314 order
Seq 308-314 Hetero dimer : IID00111Complex
 Evidence X-RAY 4kv4 B Reference
       Region 4kv4 B 308-312 order
       Region 4kv4 B 313-314 disorder
Seq 428-551
 Evidence NMR Reference
       Region 428-551 order
Seq 521-551 Hetero dimer : IID50021Complex
 Evidence NMR 5urn B Reference
       Region 5urn B 521-551 order
       Region 5urn B 521-531 high_rmsd
       Region 5urn B 550-551 high_rmsd
Seq 521-551 Hetero dimer : IID50008Complex
 Evidence NMR 5u4k B Reference
       Region 5u4k B 521-551 order
       Region 5u4k B 521-530 high_rmsd
SeqProS verified 292-320 Hetero trimer : IID00654Complex,P19838
       Region 1nfi C 20-320 order
SeqProS verified 521-551 Hetero dimer : IID50008Complex
       Region 5u4k B 521-551 order
       Region 428-551 order
SeqProS verified 521-551 Hetero dimer : IID50021Complex
       Region 5urn B 521-551 order
       Region 428-551 order
Seqphosphorylation
    254-254 Phosphothreonine
    276-276 Phosphoserine; by RPS6KA4 and RPS6KA5
    281-281 Phosphoserine
    311-311 Phosphoserine; by PKC/PRKCZ
    435-435 Phosphothreonine
    468-468 Phosphoserine; by IKKB and IKKE
    505-505 Phosphothreonine; by CHEK1
    529-529 Phosphoserine; by CK2
    536-536 Phosphoserine; by IKKB
Seqacetylation
    1-1 N-acetylmethionine
    122-122 N6-acetyllysine; by PCAF and EP300; alternate
    123-123 N6-acetyllysine; by PCAF and EP300; alternate
    218-218 N6-acetyllysine
    221-221 N6-acetyllysine
    310-310 N6-acetyllysine; alternate
 
Prediction
DICHOT
Disorder 1-19,296-431,492-551
Known Domain 20-295,432-491
SCOPe RPS-Blast
     1nfiA2 20-189 3e-56 b.2.5.3 Dorsal homologue Gambif1
     1my7A 191-297 9e-33 b.1.18.1 Calmodulin binding transcription activa...
SCOP Hmmer
     1nfkA2 18-196 4.7e-76 b.2.5.3 Dorsal homologue ...
     1oy3C_ 191-323 1.5e-54 b.1.18.1 Calmodulin bind...
Pfam RPS-Blast
     PF00554 21-186 2e-28 Rel homology DNA-binding dom...
     PF16179 195-290 4e-29 Rel homology dimerisation d...
Pfam Hmmer
    PF00554 21-186 2.3e-73 Rel homology DNA-binding do...
    PF16179 195-291 1.7e-40 Rel homology dimerisation ...