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IID00209  Ubiquitin-protein ligase E3A (Homo sapiens) Q05086
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
875
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 24-87 Monomer :
 Evidence NMR 2kr1 A Reference
       Region 2kr1 A 24-87 order
       Region 2kr1 A 24-25 high_rmsd
       Region 2kr1 A 86-87 high_rmsd
Seqdisorder 401-418
 Evidence CD Reference
       Region 401-418 disorder
Seq 401-418 Monomer :
 Evidence NMR 1eqx A Reference
       Region 1eqx A 401-418 order
       Region 1eqx A 401-401 high_rmsd
Seq 403-414 Hetero trimer : IID90005Complex,IID90020Complex
 Evidence X-RAY 4giz A Reference
       Region 4giz A 403-414 order
Seq 403-414 Hetero trimer : IID90005Complex,IID90020Complex
 Evidence X-RAY 4giz B Reference
       Region 4giz B 403-414 order
Seq 406-417 Hetero tetramer : IID00015Complex,IID90005Complex,IID90020Complex
 Evidence X-RAY 4xr8 A Reference
       Region 4xr8 A 406-417 order
Seq 406-417 Hetero tetramer : IID00015Complex,IID90005Complex,IID90020Complex
 Evidence X-RAY 4xr8 B Reference
       Region 4xr8 B 406-416 order
       Region 4xr8 B 417-417 disorder
Seq 518-875 Hetero tetramer : IID00592Complex
 Evidence X-RAY 1c4z A Reference
       Region 1c4z A 518-519 disorder
       Region 1c4z A 520-869 order
       Region 1c4z A 870-875 disorder
 Evidence X-RAY 1c4z B Reference
       Region 1c4z B 518-519 disorder
       Region 1c4z B 520-869 order
       Region 1c4z B 870-875 disorder
 Evidence X-RAY 1c4z C Reference
       Region 1c4z C 518-519 disorder
       Region 1c4z C 520-869 order
       Region 1c4z C 870-875 disorder
Seq 518-875 Homo trimer :
 Evidence X-RAY 1d5f A Reference
       Region 1d5f A 518-519 disorder
       Region 1d5f A 520-869 order
       Region 1d5f A 870-875 disorder
 Evidence X-RAY 1d5f B Reference
       Region 1d5f B 518-519 disorder
       Region 1d5f B 520-869 order
       Region 1d5f B 870-875 disorder
 Evidence X-RAY 1d5f C Reference
       Region 1d5f C 518-519 disorder
       Region 1d5f C 520-869 order
       Region 1d5f C 870-875 disorder
SeqProS verified 403-416 Hetero tetramer : IID00015Complex,IID90005Complex,IID90020Complex
       Region 4xr8 A 406-417 order
       Region 401-418 disorder
SeqProS verified 403-416 Hetero trimer : IID90005Complex,IID90020Complex
       Region 4giz B 403-414 order
       Region 401-418 disorder
SeqProS verified 403-416 Hetero tetramer : IID00015Complex,IID90005Complex,IID90020Complex
       Region 4xr8 B 406-416 order
       Region 401-418 disorder
SeqProS verified 403-416 Hetero trimer : IID90005Complex,IID90020Complex
       Region 4giz A 403-414 order
       Region 401-418 disorder
Seqphosphorylation
    218-218 Phosphoserine
    659-659 Phosphotyrosine; by ABL1
 
Prediction
DICHOT
Disorder 1-23,88-441,507-519,870-875
Known Domain 24-87,520-869
Cryptic Domain 442-506
SCOPe RPS-Blast
     1c4zA 520-869 0.0 d.148.1.1 Ubiquitin-protein ligase E3a (E6ap)
SCOP Hmmer
     1c4zA_ 521-868 1.4e-123 d.148.1.1 Ubiquitin-pro...
Pfam RPS-Blast
     PF16558 29-83 6e-14 Amino-terminal Zinc-binding d...
     PF00632 577-874 3e-14 HECT-domain (ubiquitin-tran...
Pfam Hmmer
    PF16558 29-83 1.6e-21 Amino-terminal Zinc-binding ...
    PF00632 577-874 1.5e-96 HECT-domain (ubiquitin-tra...