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IID00225  Nuclear RNA export factor 1 (Homo sapiens) Q9UBU9
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
619
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 53-82 Hetero dimer : IID00094Complex
 Evidence X-RAY 2z5k B Reference
       Region 2z5k B 53-67 disorder
       Region 2z5k B 68-79 order
       Region 2z5k B 80-82 disorder
 Evidence X-RAY 2z5m B Reference
       Region 2z5m B 53-69 disorder
       Region 2z5m B 70-79 order
       Region 2z5m B 80-82 disorder
Seq 96-362 Monomer :
 Evidence X-RAY 3rw6 A This region binds to RNA. Reference
       Region 3rw6 A 96-117 disorder
       Region 3rw6 A 118-362 order
 Evidence X-RAY 3rw6 B This region binds to RNA. Reference
       Region 3rw6 B 96-116 disorder
       Region 3rw6 B 117-360 order
       Region 3rw6 B 361-362 disorder
Seq 96-372 Homo dimer :
 Evidence X-RAY 1koh A Reference
       Region 1koh A 96-104 disorder
       Region 1koh A 105-362 order
       Region 1koh A 363-372 disorder
 Evidence X-RAY 1koh C Reference
       Region 1koh C 96-103 disorder
       Region 1koh C 104-362 order
       Region 1koh C 363-372 disorder
 Evidence X-RAY 1koh B Reference
       Region 1koh B 96-200 disorder
       Region 1koh B 201-367 order
       Region 1koh B 368-372 disorder
 Evidence X-RAY 1koh D Reference
       Region 1koh D 96-200 disorder
       Region 1koh D 201-372 order
 Evidence X-RAY 1koo A Reference
       Region 1koo A 96-104 disorder
       Region 1koo A 105-362 order
       Region 1koo A 363-372 disorder
 Evidence X-RAY 1koo C Reference
       Region 1koo C 96-100 disorder
       Region 1koo C 101-362 order
       Region 1koo C 363-372 disorder
 Evidence X-RAY 1koo B Reference
       Region 1koo B 96-202 disorder
       Region 1koo B 203-367 order
       Region 1koo B 368-372 disorder
 Evidence X-RAY 1koo D Reference
       Region 1koo D 96-203 disorder
       Region 1koo D 204-372 order
 Evidence X-RAY 3rw7 A Reference
       Region 3rw7 A 96-117 disorder
       Region 3rw7 A 118-199 order
       Region 3rw7 A 200-202 disorder
       Region 3rw7 A 203-362 order
 Evidence X-RAY 3rw7 C Reference
       Region 3rw7 C 96-116 disorder
       Region 3rw7 C 117-198 order
       Region 3rw7 C 199-202 disorder
       Region 3rw7 C 203-362 order
 Evidence X-RAY 3rw7 B Reference
       Region 3rw7 B 96-202 disorder
       Region 3rw7 B 203-362 order
 Evidence X-RAY 3rw7 D Reference
       Region 3rw7 D 96-203 disorder
       Region 3rw7 D 204-362 order
Seq 96-555 Hetero tetramer : IID00399Complex
 Evidence X-RAY 4wyk A Reference
       Region 4wyk A 96-202 disorder
       Region 4wyk A 203-423 order
       Region 4wyk A 424-426 disorder
       Region 4wyk A 427-549 order
       Region 4wyk A 550-555 disorder
 Evidence X-RAY 4wyk C Reference
       Region 4wyk C 96-201 disorder
       Region 4wyk C 202-424 order
       Region 4wyk C 425-426 disorder
       Region 4wyk C 427-549 order
       Region 4wyk C 550-555 disorder
Seq 102-372 Hetero trimer :
 Evidence X-RAY 1ft8 A Reference
       Region 1ft8 A 102-117 disorder
       Region 1ft8 A 118-199 order
       Region 1ft8 A 200-202 disorder
       Region 1ft8 A 203-362 order
       Region 1ft8 A 363-372 disorder
 Evidence X-RAY 1ft8 C Reference
       Region 1ft8 C 102-116 disorder
       Region 1ft8 C 117-198 order
       Region 1ft8 C 199-200 disorder
       Region 1ft8 C 201-362 order
       Region 1ft8 C 363-372 disorder
 Evidence X-RAY 1ft8 B Reference
       Region 1ft8 B 102-202 disorder
       Region 1ft8 B 203-367 order
       Region 1ft8 B 368-372 disorder
 Evidence X-RAY 1ft8 D Reference
       Region 1ft8 D 102-203 disorder
       Region 1ft8 D 204-365 order
       Region 1ft8 D 366-372 disorder
 Evidence X-RAY 1ft8 E Reference
       Region 1ft8 E 102-118 disorder
       Region 1ft8 E 119-123 order
       Region 1ft8 E 124-130 disorder
       Region 1ft8 E 131-153 order
       Region 1ft8 E 154-159 disorder
       Region 1ft8 E 160-175 order
       Region 1ft8 E 176-372 disorder
Seq 102-372 Homo dimer :
 Evidence X-RAY 1fo1 A Reference
       Region 1fo1 A 102-122 disorder
       Region 1fo1 A 123-143 order
       Region 1fo1 A 144-146 disorder
       Region 1fo1 A 147-159 order
       Region 1fo1 A 160-170 disorder
       Region 1fo1 A 171-191 order
       Region 1fo1 A 192-202 disorder
       Region 1fo1 A 203-362 order
       Region 1fo1 A 363-372 disorder
 Evidence X-RAY 1fo1 B Reference
       Region 1fo1 B 102-202 disorder
       Region 1fo1 B 203-365 order
       Region 1fo1 B 366-372 disorder
Seq 371-619 Hetero trimer : IID00399Complex
 Evidence X-RAY 1jn5 B Reference
       Region 1jn5 B 371-423 order
       Region 1jn5 B 424-427 disorder
       Region 1jn5 B 428-555 order
       Region 1jn5 B 556-619 disorder
Seq 371-619 Hetero dimer : IID00399Complex
 Evidence X-RAY 1jkg B Reference
       Region 1jkg B 371-423 order
       Region 1jkg B 424-429 disorder
       Region 1jkg B 430-555 order
       Region 1jkg B 556-619 disorder
Seq 551-619 Monomer :
 Evidence NMR 1go5 A Reference
       Region 1go5 A 551-619 order
       Region 1go5 A 551-562 disorder
       Region 1go5 A 551-561 high_rmsd
       Region 1go5 A 563-619 order
Seq 561-619 Hetero dimer :
 Evidence X-RAY 1oai A Reference
       Region 1oai A 561-619 order
SeqProS possible 68-79 Nuclear Localization Signal (NLS) Hetero dimer : IID00094Complex
       Region 2z5m B 70-79 order
       Region 2z5k B 68-79 order
SeqProS verified 194-204 :
       Region 3rw6 A 118-362 order
       Region 3rw6 B 117-360 order
       Region 3rw7 A 200-202 disorder
       Region 3rw7 C 199-202 disorder
Seqphosphorylation
    9-9 Phosphoserine
Seqacetylation
    2-2 N-acetylalanine
 
Prediction
DICHOT
Disorder 1-118,176-202,550-565
Known Domain 119-175,203-549,566-619
SCOPe RPS-Blast
     3rw7A1 118-199 1e-33 d.58.7.0 automated matches
     3rw7A2 203-362 1e-59 c.10.2.3 mRNA export factor tap
     1jkgB1 371-555 4e-65 d.17.4.2 mRNA transport regulator MTR2
     1oaiA 561-619 2e-23 a.5.2.3 FG-binding, C-terminal domain of TAP
SCOP Hmmer
     1kohA2 109-199 1.4e-39 d.58.7.2 mRNA export fac...
     1fo1A1 204-359 8.4e-36 c.10.2.3 mRNA export fac...
     1jkgB_ 370-554 1.3e-67 NTF2-like
     1go5A_ 551-619 4.4e-29 a.5.2.3 FG-binding, C-te...
Pfam RPS-Blast
     PF09162 117-198 2e-29 Tap, RNA-binding
     PF13855 270-327 9e-06 Leucine rich repeat
     PF02136 387-535 2e-04 Nuclear transport factor 2 ...
     PF03943 571-617 2e-14 TAP C-terminal domain
Pfam Hmmer
    PF09162 116-198 1.4e-42 Tap, RNA-binding
    PF02136 387-535 1.4e-31 Nuclear transport factor 2...
    PF03943 569-617 2.3e-28 TAP C-terminal domain