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IID00232  ATP-dependent RNA helicase DDX3X (Homo sapiens) O00571
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
662
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2-10 Hetero trimer : P30475
 Evidence X-RAY 4o2c C Reference
       Region 4o2c C 2-10 order
 Evidence X-RAY 4o2e C Reference
       Region 4o2e C 2-10 order
 Evidence X-RAY 4o2e F Reference
       Region 4o2e F 2-10 order
 Evidence X-RAY 4o2f C Reference
       Region 4o2f C 3-10 order
 Evidence X-RAY 4o2f F Reference
       Region 4o2f F 3-10 order
Seqdisorder 5-167
 Evidence CD Reference
       Region 5-167 disorder
Seq 71-90 Hetero pentamer : IID90010Complex
 Evidence X-RAY 3jrv C Reference
       Region 3jrv C 71-80 disorder
       Region 3jrv C 81-89 order
       Region 3jrv C 90-90 disorder
 Evidence X-RAY 3jrv D Reference
       Region 3jrv D 71-81 disorder
       Region 3jrv D 82-88 order
       Region 3jrv D 89-90 disorder
 Evidence X-RAY 3jrv E Reference
       Region 3jrv E 71-81 disorder
       Region 3jrv E 82-86 order
       Region 3jrv E 87-90 disorder
Seq 133-584 Monomer :
 Evidence X-RAY 5e7i B Reference
       Region 5e7i B 133-133 disorder
       Region 5e7i B 134-153 order
       Region 5e7i B 154-165 disorder
       Region 5e7i B 166-256 order
       Region 5e7i B 257-262 disorder
       Region 5e7i B 263-472 order
       Region 5e7i B 473-480 disorder
       Region 5e7i B 481-577 order
       Region 5e7i B 578-584 disorder
 Evidence X-RAY 5e7i A Reference
       Region 5e7i A 133-133 disorder
       Region 5e7i A 134-153 order
       Region 5e7i A 154-163 disorder
       Region 5e7i A 164-256 order
       Region 5e7i A 257-260 disorder
       Region 5e7i A 261-577 order
       Region 5e7i A 578-584 disorder
 Evidence X-RAY 5e7i C Reference
       Region 5e7i C 133-133 disorder
       Region 5e7i C 134-153 order
       Region 5e7i C 154-164 disorder
       Region 5e7i C 165-255 order
       Region 5e7i C 256-262 disorder
       Region 5e7i C 263-575 order
       Region 5e7i C 576-584 disorder
 Evidence X-RAY 5e7j A Reference
       Region 5e7j A 133-154 order
       Region 5e7j A 155-165 disorder
       Region 5e7j A 166-255 order
       Region 5e7j A 256-263 disorder
       Region 5e7j A 264-584 order
 Evidence X-RAY 5e7m A Reference
       Region 5e7m A 133-133 disorder
       Region 5e7m A 134-153 order
       Region 5e7m A 154-165 disorder
       Region 5e7m A 166-255 order
       Region 5e7m A 256-261 disorder
       Region 5e7m A 262-575 order
       Region 5e7m A 576-584 disorder
 Evidence X-RAY 2i4i A Reference
       Region 2i4i A 168-406 order
       Region 2i4i A 407-410 disorder
       Region 2i4i A 411-534 order
       Region 2i4i A 535-536 disorder
       Region 2i4i A 537-580 order
       Region 2i4i A 581-582 disorder
 Evidence X-RAY 4pxa A Reference
       Region 4pxa A 135-576 order
       Region 4pxa A 577-582 disorder
Seq 135-407 Monomer :
 Evidence X-RAY 4px9 A Reference
       Region 4px9 A 135-151 order
       Region 4px9 A 152-162 disorder
       Region 4px9 A 163-407 order
 Evidence X-RAY 4px9 B Reference
       Region 4px9 B 135-151 order
       Region 4px9 B 152-162 disorder
       Region 4px9 B 163-407 order
 Evidence X-RAY 4px9 C Reference
       Region 4px9 C 135-407 order
Seq 409-580 Monomer :
 Evidence X-RAY 2jgn A Reference
       Region 2jgn A 409-410 disorder
       Region 2jgn A 411-438 order
       Region 2jgn A 439-439 disorder
       Region 2jgn A 440-472 order
       Region 2jgn A 473-480 disorder
       Region 2jgn A 481-499 order
       Region 2jgn A 500-505 disorder
       Region 2jgn A 506-576 order
       Region 2jgn A 577-580 disorder
 Evidence X-RAY 2jgn B Reference
       Region 2jgn B 409-439 order
       Region 2jgn B 440-441 disorder
       Region 2jgn B 442-501 order
       Region 2jgn B 502-506 disorder
       Region 2jgn B 507-576 order
       Region 2jgn B 577-580 disorder
 Evidence X-RAY 2jgn C Reference
       Region 2jgn C 409-411 disorder
       Region 2jgn C 412-436 order
       Region 2jgn C 437-437 disorder
       Region 2jgn C 438-439 order
       Region 2jgn C 440-441 disorder
       Region 2jgn C 442-476 order
       Region 2jgn C 477-479 disorder
       Region 2jgn C 480-575 order
       Region 2jgn C 576-580 disorder
SeqProS verified 81-89 Hetero pentamer : IID90010Complex
       Region 3jrv C 81-89 order
       Region 3jrv D 82-88 order
       Region 5-167 disorder
Seqphosphorylation
    82-82 Phosphoserine
    86-86 Phosphoserine
    90-90 Phosphoserine
    102-102 Phosphoserine; by IKKE
    104-104 Phosphotyrosine
    131-131 Phosphoserine
    183-183 Phosphoserine
    456-456 Phosphoserine
    594-594 Phosphoserine
    605-605 Phosphoserine
    612-612 Phosphoserine
Seqacetylation
    2-2 N-acetylserine
    55-55 N6-acetyllysine
    118-118 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-167,581-662
Known Domain 168-580
SCOPe RPS-Blast
     2i4iA3 168-406 e-128 c.37.1.0 automated matches
     5nt7B 415-574 1e-78 c.37.1.0 automated matches
SCOP Hmmer
     1w36D1 130-364 2.4e-18 c.37.1.19 ATP-dependent ...
     1wp9A2 268-554 4.6e-76 c.37.1.19 ATP-dependent ...
Pfam RPS-Blast
     PF16203 471-537 4e-04 ERCC3/RAD25/XPB C-terminal ...
Pfam Hmmer
    PF00270 204-391 8.9e-55 DEAD/DEAH box helicase
    PF00271 426-536 2.5e-35 Helicase conserved C-termi...