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IID00239  Histone H3.3 (Homo sapiens) P84243
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
136
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-134 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 5ay8 A Reference
       Region 5ay8 A 1-38 disorder
       Region 5ay8 A 39-134 order
 Evidence X-RAY 5ay8 E Reference
       Region 5ay8 E 1-38 disorder
       Region 5ay8 E 39-134 order
Seq 1-136 Hetero octamer : IID00016Complex,IID00019Complex,IID00058Complex
 Evidence X-RAY 5b32 A Reference
       Region 5b32 A 1-38 disorder
       Region 5b32 A 39-135 order
       Region 5b32 A 136-136 disorder
 Evidence X-RAY 5b32 E Reference
       Region 5b32 E 1-38 disorder
       Region 5b32 E 39-136 order
Seq 1-136 Hetero octamer : IID00019Complex,IID00058Complex
 Evidence X-RAY 5b33 A Reference
       Region 5b33 A 1-38 disorder
       Region 5b33 A 39-135 order
       Region 5b33 A 136-136 disorder
 Evidence X-RAY 5b33 E Reference
       Region 5b33 E 1-38 disorder
       Region 5b33 E 39-136 order
Seq 1-136 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 3av2 A Reference
       Region 3av2 A 1-38 disorder
       Region 3av2 A 39-135 order
       Region 3av2 A 136-136 disorder
 Evidence X-RAY 3av2 E Reference
       Region 3av2 E 1-38 disorder
       Region 3av2 E 39-136 order
Seq 1-136 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 5x7x A Reference
       Region 5x7x A 1-38 disorder
       Region 5x7x A 39-134 order
       Region 5x7x A 135-136 disorder
 Evidence X-RAY 5x7x E Reference
       Region 5x7x E 1-36 disorder
       Region 5x7x E 37-135 order
       Region 5x7x E 136-136 disorder
Seq 1-136 Hetero trimer : IID00058Complex,IID00398Complex
 Evidence X-RAY 4h9n A Reference
       Region 4h9n A 2-37 disorder
       Region 4h9n A 38-135 order
       Region 4h9n A 136-136 disorder
 Evidence X-RAY 4h9o A Reference
       Region 4h9o A 2-38 disorder
       Region 4h9o A 39-135 order
       Region 4h9o A 136-136 disorder
 Evidence X-RAY 4h9p A Reference
       Region 4h9p A 2-37 disorder
       Region 4h9p A 38-135 order
       Region 4h9p A 136-136 disorder
 Evidence X-RAY 4h9q A Reference
       Region 4h9q A 2-37 disorder
       Region 4h9q A 38-135 order
       Region 4h9q A 136-136 disorder
 Evidence X-RAY 4h9r A Reference
       Region 4h9r A 2-37 disorder
       Region 4h9r A 38-135 order
       Region 4h9r A 136-136 disorder
 Evidence X-RAY 4h9s A Reference
       Region 4h9s A 2-45 disorder
       Region 4h9s A 46-134 order
       Region 4h9s A 135-136 disorder
 Evidence X-RAY 4h9s B Reference
       Region 4h9s B 2-40 disorder
       Region 4h9s B 41-134 order
       Region 4h9s B 135-136 disorder
 Evidence X-RAY 4hga B Reference
       Region 4hga B 1-43 disorder
       Region 4hga B 44-136 order
Seq 1-136 Hetero octamer : IID00016Complex,IID00058Complex,IID00272Complex
 Evidence X-RAY 3wtp E Reference
       Region 3wtp E 1-36 disorder
       Region 3wtp E 37-136 order
Seq 2-12 Hetero dimer : IID00552Complex
 Evidence X-RAY 4tmp B Reference
       Region 4tmp B 2-3 disorder
       Region 4tmp B 4-11 order
       Region 4tmp B 12-12 disorder
 Evidence X-RAY 4tmp D Reference
       Region 4tmp D 2-3 disorder
       Region 4tmp D 4-11 order
       Region 4tmp D 12-12 disorder
Seq 2-12 Hetero dimer : IID00327Complex
 Evidence X-RAY 3asl B Reference
       Region 3asl B 2-10 order
       Region 3asl B 11-12 disorder
Seq 2-12 Hetero tetramer : Q504Y3
 Evidence X-RAY 4o62 D Reference
       Region 4o62 D 2-7 order
       Region 4o62 D 8-12 disorder
Seq 2-13 Hetero dimer : IID00485Complex
 Evidence X-RAY 4l58 B Reference
       Region 4l58 B 2-8 order
       Region 4l58 B 9-13 disorder
Seq 2-13 Hetero hexamer : IID00336Complex
 Evidence X-RAY 4u7t F Reference
       Region 4u7t F 2-11 order
       Region 4u7t F 12-13 disorder
 Evidence X-RAY 4u7t G Reference
       Region 4u7t G 2-11 order
       Region 4u7t G 12-13 disorder
Seq 2-13 Hetero dimer : O95696
 Evidence NMR 2l43 A Reference
       Region 2l43 A 2-13 order
       Region 2l43 A 10-13 high_rmsd
Seq 2-14
 Evidence X-RAY 3ask R The all of the chain R is disordered but K9 is ordered. Reference
       Region 3ask R 2-9 disorder
       Region 3ask R 10-10 order
       Region 3ask R 11-14 disorder
Seq 2-16 Hetero dimer : IID00496Complex
 Evidence X-RAY 4gne B Reference
       Region 4gne B 2-7 order
       Region 4gne B 8-8 disorder
 Evidence X-RAY 4gnf C Reference
       Region 4gnf C 2-10 order
       Region 4gnf C 11-16 disorder
 Evidence X-RAY 4gng B Reference
       Region 4gng B 2-11 order
       Region 4gng B 12-16 disorder
 Evidence X-RAY 4gng F Reference
       Region 4gng F 2-11 order
       Region 4gng F 12-16 disorder
Seq 2-16 Hetero tetramer : Q14149
 Evidence X-RAY 4qq4 C Reference
       Region 4qq4 C 2-9 order
       Region 4qq4 C 10-16 disorder
 Evidence X-RAY 4qq4 D Reference
       Region 4qq4 D 2-9 order
       Region 4qq4 D 10-16 disorder
Seq 2-16 Hetero dimer : IID00303Complex
 Evidence X-RAY 3ql9 C Reference
       Region 3ql9 C 2-11 order
       Region 3ql9 C 12-16 disorder
 Evidence X-RAY 3qla C Reference
       Region 3qla C 2-11 order
       Region 3qla C 12-16 disorder
 Evidence X-RAY 3qla F Reference
       Region 3qla F 2-11 order
       Region 3qla F 12-16 disorder
 Evidence X-RAY 3qlc C Reference
       Region 3qlc C 2-8 order
       Region 3qlc C 9-16 disorder
 Evidence X-RAY 3qlc D Reference
       Region 3qlc D 2-8 order
       Region 3qlc D 9-16 disorder
 Evidence X-RAY 4w5a C Reference
       Region 4w5a C 2-12 order
       Region 4w5a C 13-16 disorder
 Evidence X-RAY 4w5a D Reference
       Region 4w5a D 2-13 order
       Region 4w5a D 14-16 disorder
 Evidence X-RAY 4w5a F Reference
       Region 4w5a F 2-12 order
       Region 4w5a F 13-16 disorder
Seq 2-18 Hetero hexamer : IID00327Complex
 Evidence X-RAY 3ask P The all of the chain R is disordered but K9 is ordered. Reference
       Region 3ask P 2-11 order
       Region 3ask P 12-14 disorder
 Evidence X-RAY 3ask Q The all of the chain R is disordered but K9 is ordered. Reference
       Region 3ask Q 2-10 order
       Region 3ask Q 11-14 disorder
 Evidence X-RAY 4gy5 E Reference
       Region 4gy5 E 2-11 order
       Region 4gy5 E 12-18 disorder
 Evidence X-RAY 4gy5 F Reference
       Region 4gy5 F 2-10 order
       Region 4gy5 F 11-18 disorder
Seq 2-22 Hetero trimer : IID00487Complex
 Evidence X-RAY 4gur C Reference
       Region 4gur C 2-21 order
       Region 4gur C 22-22 disorder
 Evidence X-RAY 4gus C Reference
       Region 4gus C 2-21 order
       Region 4gus C 22-22 disorder
Seq 2-27 Hetero trimer : IID00487Complex
 Evidence X-RAY 4gu0 E Reference
       Region 4gu0 E 2-27 order
 Evidence X-RAY 4gu0 F Reference
       Region 4gu0 F 2-27 order
Seq 2-136 Hetero tetramer : IID00058Complex,IID00398Complex,Q1HVJ0
 Evidence X-RAY 5kdm A Reference
       Region 5kdm A 2-37 disorder
       Region 5kdm A 38-136 order
Seq 13-20 Hetero dimer : IID50100Complex
 Evidence X-RAY 3jvk C Reference
       Region 3jvk C 13-16 order
       Region 3jvk C 17-20 disorder
 Evidence X-RAY 3mul D Reference
       Region 3mul D 13-15 order
       Region 3mul D 16-20 disorder
Seq 14-31 Hetero tetramer : Q86X55
 Evidence X-RAY 5dx0 F Reference
       Region 5dx0 F 14-21 order
       Region 5dx0 F 22-31 disorder
 Evidence X-RAY 5dx0 G Reference
       Region 5dx0 G 14-22 order
       Region 5dx0 G 23-31 disorder
 Evidence X-RAY 5dx0 H Reference
       Region 5dx0 H 14-21 order
       Region 5dx0 H 22-31 disorder
 Evidence X-RAY 5dx0 I Reference
       Region 5dx0 I 14-22 order
       Region 5dx0 I 23-31 disorder
Seq 14-31 Hetero trimer : Q86X55
 Evidence X-RAY 5dwq F Reference
       Region 5dwq F 14-22 order
       Region 5dwq F 23-31 disorder
 Evidence X-RAY 5dwq G Reference
       Region 5dwq G 14-21 order
       Region 5dwq G 22-31 disorder
Seq 20-43 Hetero dimer : Q8R5C8
 Evidence X-RAY 4n4i B Reference
       Region 4n4i B 20-29 disorder
       Region 4n4i B 30-40 order
       Region 4n4i B 41-43 disorder
Seq 22-29 Hetero dimer : IID50100Complex
 Evidence X-RAY 3muk D Reference
       Region 3muk D 22-28 order
       Region 3muk D 29-29 disorder
Seq 30-43 Hetero dimer : Q9BYW2
 Evidence X-RAY 5jjy B Reference
       Region 5jjy B 30-43 order
 Evidence X-RAY 5jlb B Reference
       Region 5jlb B 30-43 order
Seq 58-136 Hetero octamer : IID00058Complex,P49736,Q96HA7
 Evidence X-RAY 5ja4 A Reference
       Region 5ja4 A 58-135 order
       Region 5ja4 A 136-136 disorder
Seq 58-136 Hetero tetramer : IID00058Complex,P49736,Q9NVP2
 Evidence X-RAY 5bnx A Reference
       Region 5bnx A 58-58 disorder
       Region 5bnx A 59-135 order
       Region 5bnx A 136-136 disorder
Seq 58-136 Hetero hexamer : IID00058Complex,P49736
 Evidence X-RAY 5bnv A Reference
       Region 5bnv A 58-58 disorder
       Region 5bnv A 59-135 order
       Region 5bnv A 136-136 disorder
 Evidence X-RAY 5bnv D Reference
       Region 5bnv D 58-58 disorder
       Region 5bnv D 59-136 order
SeqProS verified 2-7 Hetero tetramer : Q504Y3
       Region 4o62 D 2-7 order
       Region 3av2 A 1-38 disorder
SeqProS verified 2-8 Hetero dimer : IID00485Complex
       Region 4l58 B 2-8 order
       Region 3av2 A 1-38 disorder
SeqProS verified 2-9 Hetero tetramer : Q14149
       Region 4qq4 C 2-9 order
       Region 4qq4 D 2-9 order
       Region 3av2 A 1-38 disorder
SeqProS verified 2-10 Hetero dimer : IID00327Complex
       Region 3asl B 2-10 order
       Region 3av2 A 1-38 disorder
SeqProS verified 2-11 Hetero hexamer : IID00327Complex
       Region 3ask P 2-11 order
       Region 3ask Q 2-10 order
       Region 4gy5 E 2-11 order
       Region 4gy5 F 2-10 order
       Region 3av2 A 1-38 disorder
SeqProS verified 2-11 Hetero dimer : IID00496Complex
       Region 4gnf C 2-10 order
       Region 4gne B 2-7 order
       Region 4gng B 2-11 order
       Region 4gng F 2-11 order
       Region 3av2 A 1-38 disorder
SeqProS verified 2-11 Hetero hexamer : IID00336Complex
       Region 4u7t F 2-11 order
       Region 4u7t G 2-11 order
       Region 3av2 A 1-38 disorder
SeqProS verified 2-13 Hetero dimer : IID00303Complex
       Region 4w5a C 2-12 order
       Region 4w5a D 2-13 order
       Region 4w5a F 2-12 order
       Region 3ql9 C 2-11 order
       Region 3qla C 2-11 order
       Region 3qla F 2-11 order
       Region 3qlc C 2-8 order
       Region 3qlc D 2-8 order
       Region 3av2 A 1-38 disorder
SeqProS verified 2-21 Hetero trimer : IID00487Complex
       Region 4gur C 2-21 order
       Region 4gus C 2-21 order
       Region 3av2 A 1-38 disorder
SeqProS verified 2-27 Hetero trimer : IID00487Complex
       Region 4gu0 E 2-27 order
       Region 4gu0 F 2-27 order
       Region 3av2 A 1-38 disorder
SeqProS verified 4-11 Hetero dimer : IID00552Complex
       Region 4tmp B 4-11 order
       Region 4tmp D 4-11 order
       Region 3av2 A 1-38 disorder
SeqProS verified 13-16 Histone H3K23 is propionyl lysine Hetero dimer : IID50100Complex
       Region 3jvk C 13-16 order
       Region 3mul D 13-15 order
       Region 3av2 A 1-38 disorder
SeqProS verified 14-22 Hetero tetramer : Q86X55
       Region 5dx0 F 14-21 order
       Region 5dx0 G 14-22 order
       Region 5dx0 H 14-21 order
       Region 5dx0 I 14-22 order
       Region 3av2 A 1-38 disorder
SeqProS verified 14-22 Hetero trimer : Q86X55
       Region 5dwq F 14-22 order
       Region 5dwq G 14-21 order
       Region 3av2 A 1-38 disorder
SeqProS verified 22-28 Histone H3K23 is propionyl lysine. Hetero dimer : IID50100Complex
       Region 3muk D 22-28 order
       Region 3av2 A 1-38 disorder
SeqProS verified 30-40 Hetero dimer : Q8R5C8
       Region 4n4i B 30-40 order
       Region 3av2 A 1-38 disorder
SeqProS verified 30-43 Hetero dimer : Q9BYW2
       Region 5jlb B 30-43 order
       Region 5jjy B 30-43 order
       Region 3av2 A 1-38 disorder
Seqphosphorylation
    4-4 Phosphothreonine; by HASPIN
    7-7 Phosphothreonine; by PKC
    11-11 Phosphoserine; alternate; by AURKB
    12-12 Phosphothreonine; by PKC
    29-29 Phosphoserine; alternate; by AURKB
    32-32 Phosphoserine
    42-42 Phosphotyrosine
    58-58 Phosphoserine
    81-81 Phosphothreonine
    87-87 Phosphoserine
    108-108 Phosphothreonine
Seqacetylation
    5-5 N6-acetyllysine; alternate
    10-10 N6-acetyllysine; alternate
    15-15 N6-acetyllysine; alternate
    19-19 N6-acetyllysine; alternate
    24-24 N6-acetyllysine; alternate
    28-28 N6-acetyllysine; alternate
    37-37 N6-acetyllysine; alternate
    57-57 N6-acetyllysine; alternate
    80-80 N6-acetyllysine; alternate
    116-116 N6-acetyllysine
    123-123 N6-acetyllysine; alternate
 
Prediction
DICHOT
Disorder 1-1
Known Domain 2-136
SCOPe RPS-Blast
     2hueB1 62-135 2e-24 a.22.1.1 Histone H2A
SCOP Hmmer
     1kx5A_ 2-133 5.7e-59 a.22.1.1 Histone H2A
Pfam RPS-Blast
     PF15715 1-57 6e-04 PCNA-associated factor histone...
     PF00125 106-131 6e-04 Core histone H2A/H2B/H3/H4
Pfam Hmmer
    PF00125 1-132 4.7e-58 Core histone H2A/H2B/H3/H4