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IID00322  Chromodomain-helicase-DNA-binding protein 4 (Homo sapiens) Q14839
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1912
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 145-225 Monomer :
 Evidence NMR 2n5n A Reference
       Region 2n5n A 145-225 order
       Region 2n5n A 145-147 high_rmsd
       Region 2n5n A 220-225 high_rmsd
Seq 365-420 Monomer :
 Evidence NMR 2l5u A Reference
       Region 2l5u A 365-420 order
       Region 2l5u A 419-420 high_rmsd
Seq 446-501 Monomer :
 Evidence NMR 1mm2 A Reference
       Region 1mm2 A 446-501 order
       Region 1mm2 A 446-446 high_rmsd
       Region 1mm2 A 496-501 high_rmsd
 Evidence NMR 1mm3 A Reference
       Region 1mm3 A 446-501 order
       Region 1mm3 A 446-447 high_rmsd
Seq 446-501 Hetero dimer : IID00062Complex
 Evidence NMR 2l75 A Reference
       Region 2l75 A 446-501 order
       Region 2l75 A 446-446 high_rmsd
       Region 2l75 A 498-501 high_rmsd
Seq 499-677 Monomer :
 Evidence X-RAY 4o9i X Reference
       Region 4o9i X 499-527 order
       Region 4o9i X 528-531 disorder
       Region 4o9i X 532-585 order
       Region 4o9i X 586-590 disorder
       Region 4o9i X 591-677 order
Seq 618-674 Monomer :
 Evidence NMR 2ee1 A Reference
       Region 2ee1 A 618-674 order
Seqphosphorylation
    44-44 Phosphoserine
    303-303 Phosphoserine
    308-308 Phosphoserine
    309-309 Phosphoserine
    310-310 Phosphoserine
    319-319 Phosphoserine
    367-367 Phosphothreonine
    428-428 Phosphoserine
    515-515 Phosphoserine
    517-517 Phosphothreonine
    529-529 Phosphothreonine
    531-531 Phosphoserine
    703-703 Phosphothreonine
    1209-1209 Phosphoserine
    1308-1308 Phosphoserine
    1349-1349 Phosphoserine
    1370-1370 Phosphoserine
    1531-1531 Phosphoserine
    1535-1535 Phosphoserine
    1537-1537 Phosphoserine
    1542-1542 Phosphothreonine
    1549-1549 Phosphothreonine
    1553-1553 Phosphothreonine
    1570-1570 Phosphoserine
    1576-1576 Phosphoserine
    1602-1602 Phosphoserine
    1653-1653 Phosphothreonine
    1679-1679 Phosphothreonine
Seqacetylation
    1643-1643 N6-acetyllysine; alternate
 
Prediction
DICHOT
Disorder 1-156,211-364,421-446,502-541,675-725,1200-1695,1804-1847,1884-1912
Known Domain 365-420,447-501,542-674,726-1199,1729-1803
Cryptic Domain 157-210,1696-1728,1848-1883
SCOPe RPS-Blast
     1fp0A1 364-415 7e-24 g.50.1.2 Death associated transcription factor ...
     1fp0A1 444-501 2e-27 g.50.1.2 Death associated transcription factor ...
     5afwA1 502-579 4e-06 b.34.13.2 ATP-dependent helicase CHD1 (Chromo ...
     5afwA2 607-673 1e-10 b.34.13.2 ATP-dependent helicase CHD1 (Chromo ...
     1z3iX2 688-957 2e-49 c.37.1.19 ATP-dependent RNA helicase DDX25
     1z3iX1 960-1291 e-110 c.37.1.19 ATP-dependent RNA helicase DDX25
SCOP Hmmer
     1weuA_ 342-416 3.2e-18 FYVE/PHD zinc finger
     2b2yA2 464-584 1e-20 b.34.13.2 ATP-dependent he...
     2b2yA1 606-675 6e-18 b.34.13.2 ATP-dependent he...
     1z3iX2 705-957 4.1e-57 c.37.1.19 ATP-dependent ...
     1z3iX1 959-1229 3e-74 c.37.1.19 ATP-dependent R...
Pfam RPS-Blast
     PF08073 164-217 7e-18 CHDNT (NUC034) domain
     PF00628 372-414 8e-14 PHD-finger
     PF00628 452-495 1e-14 PHD-finger
     PF00385 624-672 2e-05 Chromo (CHRromatin Organisa...
     PF11496 1045-1197 5e-09 Class II histone deacetyl...
     PF06465 1292-1352 8e-18 Domain of Unknown Functio...
     PF06461 1385-1520 7e-54 Domain of Unknown Functio...
     PF05262 1565-1704 4e-04 Borrelia P83/100 protein
     PF08074 1726-1896 3e-73 CHDCT2 (NUC038) domain
Pfam Hmmer
    PF08073 165-217 8.5e-29 CHDNT (NUC034) domain
    PF00628 372-416 6.9e-14 PHD-finger
    PF00628 451-495 9e-14 PHD-finger
    PF00385 623-672 2.9e-15 Chromo (CHRromatin Organis...
    PF00176 741-1024 3.4e-62 SNF2 family N-terminal do...
    PF00271 1051-1164 2.2e-25 Helicase conserved C-ter...
    PF06465 1294-1352 9.6e-30 Domain of Unknown Functi...
    PF06461 1383-1520 1.8e-64 Domain of Unknown Functi...
    PF08074 1726-1896 1.7e-90 CHDCT2 (NUC038) domain