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IID00328  E3 ubiquitin-protein ligase SMURF1 (Homo sapiens) Q9HCE7
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
757
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 13-140 Monomer :
 Evidence X-RAY 3pyc A Reference
       Region 3pyc A 13-140 order
Seq 235-267 Hetero dimer : IID00174Complex
 Evidence NMR 2laz A Reference
       Region 2laz A 235-267 order
 Evidence NMR 2lb0 A Reference
       Region 2lb0 A 235-267 order
Seq 305-340 Hetero dimer : IID00174Complex
 Evidence NMR 2lb1 A Reference
       Region 2lb1 A 305-339 order
       Region 2lb1 A 340-340 disorder
Seq 306-340 Hetero dimer : IID00135Complex
 Evidence NMR 2ltx A Reference
       Region 2ltx A 306-340 order
       Region 2ltx A 306-306 high_rmsd
Seqphosphorylation
    200-200 Phosphoserine
 
Prediction
DICHOT
Disorder 1-12,141-225,272-297,341-374,751-757
Known Domain 13-140,226-271,298-340,375-750
SCOPe RPS-Blast
     2nq3A1 14-137 6e-22 b.7.1.1 Domain from cytosolic phospholipase A2
     4rexA1 236-271 9e-08 b.72.1.1 Amyloid beta A4 precursor protein-bin...
     4rexA1 304-342 5e-15 b.72.1.1 Amyloid beta A4 precursor protein-bin...
     3h1dA1 377-750 0.0 d.148.1.0 automated matches
SCOP Hmmer
     2nq3A1 13-138 1.8e-24 b.7.1.1 Domain from cytos...
     1i5hW_ 231-268 3.5e-11 b.72.1.1 Amyloid beta A4...
     1i5hW_ 301-341 6.3e-15 b.72.1.1 Amyloid beta A4...
     1nd7A_ 386-750 3.7e-128 Hect, E3 ligase cataly...
Pfam RPS-Blast
     PF00397 236-265 6e-06 WW domain
     PF00397 308-337 1e-07 WW domain
     PF00632 449-754 1e-18 HECT-domain (ubiquitin-tran...
Pfam Hmmer
    PF00168 14-102 1.1e-19 C2 domain
    PF00397 236-265 5.8e-10 WW domain
    PF00397 308-337 1.3e-12 WW domain
    PF00632 449-756 2.8e-105 HECT-domain (ubiquitin-tr...