IDEAL Node

IDEAL

IID00332 Methyl-CpG-binding domain protein 1 (Homo sapiens) Q9UIS9 LLPSNucleus speckle.

:order :disorder :conflict :PDB cluster :ProS :SCOP Domain :Pfam Domain

Experiment

605

order/disorder by at least rule

disorder by at least rule

order by at least rule

order/disorder by majority rule

Seq 1-75 Monomer :

Evidence NMR 1d9n A Reference

Region 1d9n A 1-75 order

Evidence NMR 1ig4 A Reference

Region 1ig4 A 1-75 order

Region 1ig4 A 1-1 high_rmsd

Region 1ig4 A 72-75 high_rmsd

Seqdisorder 22-29

Evidence NMR Reference

Region 22-29 disorder

Seq 167-222 Monomer :

Evidence NMR 4d4w A Reference

Region 4d4w A 167-222 order

Region 4d4w A 167-173 high_rmsd

Region 4d4w A 199-206 high_rmsd

Region 4d4w A 220-222 high_rmsd

Seq 330-388 Monomer :

Evidence X-RAY 5w9q A Reference

Region 5w9q A 330-332 disorder

Region 5w9q A 333-388 order

Evidence X-RAY 5w9q B Reference

Region 5w9q B 330-333 disorder

Region 5w9q B 334-339 order

Region 5w9q B 340-340 disorder

Region 5w9q B 341-388 order

SeqProS verified 22-29

This region is ordered in the complex with DNA. :

Region 1ig4 A 1-75 order

Region 22-29 disorder

Seqphosphorylation

297-297 Phosphoserine

391-391 Phosphoserine

399-399 Phosphoserine

297-297 Phosphoserine

391-391 Phosphoserine

399-399 Phosphoserine

Prediction

DICHOT

Disorder 76-340,397-605

Known Domain 1-75,341-396

SCOPe RPS-Blast

2ky8A 3-67 4e-21

3pt6A1 221-264 5e-05

3pt6A1 336-383 1e-10

SCOP Hmmer

1ub1A_ 2-103 2.3e-29

Pfam RPS-Blast

PF01429 13-75 4e-06 Methyl-CpG binding domain

PF02008 170-215 4e-05 CXXC zinc finger domain

PF02008 221-262 5e-05 CXXC zinc finger domain

PF02008 332-377 2e-09 CXXC zinc finger domain

Pfam Hmmer

PF01429 3-67 4.2e-20 Methyl-CpG binding domain

PF02008 169-215 2.6e-15 CXXC zinc finger domain

PF02008 219-262 1.8e-14 CXXC zinc finger domain

PF02008 331-377 2.5e-17 CXXC zinc finger domain