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IID00333  Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (Homo sapiens) Q9ULH1
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1129
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 323-423 Monomer :
 Evidence NMR 2da0 A Reference
       Region 2da0 A 323-423 order
       Region 2da0 A 360-362 high_rmsd
Seq 823-837 Hetero trimer : Q14247
 Evidence X-RAY 2d1x P Reference
       Region 2d1x P 823-824 disorder
       Region 2d1x P 825-833 order
       Region 2d1x P 834-837 disorder
 Evidence X-RAY 2d1x Q Reference
       Region 2d1x Q 823-824 disorder
       Region 2d1x Q 825-833 order
       Region 2d1x Q 834-837 disorder
Seq 1067-1129 Monomer :
 Evidence NMR 2ed1 A Reference
       Region 2ed1 A 1067-1129 order
 Evidence NMR 2rqt A Reference
       Region 2rqt A 1069-1129 order
Seq 1069-1129 Hetero dimer : IID00035Complex
 Evidence NMR 2rqu A Reference
       Region 2rqu A 1069-1129 order
SeqProS possible 825-833 SH3 binding region (Pro rich) Hetero trimer : Q14247
       Region 2d1x P 825-833 order
       Region 2d1x Q 825-833 order
Seqphosphorylation
    717-717 Phosphoserine
    726-726 Phosphoserine
    839-839 Phosphoserine
    843-843 Phosphoserine
    1008-1008 Phosphoserine
    1027-1027 Phosphoserine
    1041-1041 Phosphoserine
    1048-1048 Phosphothreonine
    1128-1128 Phosphoserine
 
Prediction
DICHOT
Disorder 1-59,269-318,429-436,710-1066
Known Domain 60-268,319-428,437-709,1067-1129
SCOPe RPS-Blast
     2q13A1 53-298 4e-35 a.238.1.1 Amphiphysin
     2q13A2 325-418 5e-22 b.55.1.0 automated matches
     2b0oE1 436-556 6e-57 g.45.1.0 automated matches
     2b0oE2 561-702 5e-39 d.211.1.0 automated matches
     2rqtA 1069-1129 9e-26 b.34.2.0 automated matches
SCOP Hmmer
     2elbA1 53-347 1.8e-66 a.238.1.1 Amphiphysin
     1wg7A_ 313-431 1.7e-21 PH domain-like
     1dcqA2 438-555 4.9e-40 g.45.1.1 Pyk2-associated...
     1dcqA1 560-709 1.1e-67 d.211.1.1 26S proteasome...
     1t3lA1 1053-1127 5.8e-17 b.34.2.1 53BP2
Pfam RPS-Blast
     PF16746 54-286 1e-19 BAR domain of APPL family
     PF15409 329-411 4e-06 Pleckstrin homology domain
     PF01412 441-555 3e-18 Putative GTPase activating ...
     PF13857 623-677 5e-05 Ankyrin repeats (many copie...
     PF12851 724-1059 7e-08 Oxygenase domain of the 2O...
     PF14604 1075-1120 1e-08 Variant SH3 domain
Pfam Hmmer
    PF16746 54-286 7.1e-30 BAR domain of APPL family
    PF00169 326-413 1.4e-12 PH domain
    PF01412 440-555 1.6e-38 Putative GTPase activating...
    PF12796 586-663 1.3e-11 Ankyrin repeats (3 copies)
    PF00018 1074-1121 1.9e-12 SH3 domain