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IID00348  Optineurin (Homo sapiens) Q96CV9
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
577
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 26-103 Hetero tetramer : Q9UHD2
 Evidence X-RAY 5eoa A Reference
       Region 5eoa A 26-29 disorder
       Region 5eoa A 30-101 order
       Region 5eoa A 102-103 disorder
 Evidence X-RAY 5eoa B Reference
       Region 5eoa B 26-29 disorder
       Region 5eoa B 30-102 order
       Region 5eoa B 103-103 disorder
 Evidence X-RAY 5eof A Reference
       Region 5eof A 26-28 disorder
       Region 5eof A 29-102 order
       Region 5eof A 103-103 disorder
 Evidence X-RAY 5eof B Reference
       Region 5eof B 26-28 disorder
       Region 5eof B 29-102 order
       Region 5eof B 103-103 disorder
Seq 169-185 Hetero dimer : IID00346Complex
 Evidence NMR 2lue B Reference
       Region 2lue B 169-185 order
Seq 170-181 Hetero dimer : IID00346Complex
 Evidence X-RAY 3vtw B Reference
       Region 3vtw B 170-176 disorder
       Region 3vtw B 177-181 order
Seq 170-181 Hetero dimer : IID00346Complex
 Evidence X-RAY 3vtw A Reference
       Region 3vtw A 170-176 disorder
       Region 3vtw A 177-181 order
Seq 170-181 Hetero dimer : IID00346Complex
 Evidence X-RAY 3vtv A Reference
       Region 3vtv A 170-176 disorder
       Region 3vtv A 177-181 order
Seq 170-181 Hetero dimer : IID00346Complex
 Evidence X-RAY 3vtw C Reference
       Region 3vtw C 170-176 disorder
       Region 3vtw C 177-181 order
Seq 416-510 Hetero trimer : P0CG48
 Evidence X-RAY 5b83 B Reference
       Region 5b83 B 416-442 disorder
       Region 5b83 B 443-501 order
       Region 5b83 B 502-510 disorder
 Evidence X-RAY 5b83 C Reference
       Region 5b83 C 416-444 disorder
       Region 5b83 C 445-505 order
       Region 5b83 C 506-510 disorder
 Evidence X-RAY 5b83 E Reference
       Region 5b83 E 416-452 disorder
       Region 5b83 E 453-502 order
       Region 5b83 E 503-510 disorder
 Evidence X-RAY 5b83 F Reference
       Region 5b83 F 416-446 disorder
       Region 5b83 F 447-505 order
       Region 5b83 F 506-510 disorder
Seq 548-577 Monomer :
 Evidence NMR 5aaz A Reference
       Region 5aaz A 548-577 order
       Region 5aaz A 548-549 high_rmsd
 Evidence NMR 2lo4 A Reference
       Region 2lo4 A 550-577 order
       Region 2lo4 A 550-550 high_rmsd
SeqProS possible 169-185 LIR (LC3 interaction region) motif. Hetero dimer : IID00346Complex
       Region 2lue B 169-185 order
Seqphosphorylation
    177-177 Phosphoserine; by TBK1
    198-198 Phosphoserine
    342-342 Phosphoserine
    526-526 Phosphoserine
 
Prediction
DICHOT
Disorder 1-43,352-443,503-577
Known Domain 138-351,444-502
Cryptic Domain 44-137
Pfam RPS-Blast
     PF16516 408-507 9e-10 Leucine zipper of domain CC...
     PF18414 551-576 7e-11 C2H2 type zinc-finger
Pfam Hmmer
    PF11577 37-104 2.4e-31 NF-kappa-B essential modula...
    PF16516 408-505 2.2e-33 Leucine zipper of domain C...
    PF18414 551-576 6.8e-21 C2H2 type zinc-finger