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IID00356  Histone-lysine N-methyltransferase 2D (Homo sapiens) O14686
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
5537
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 5333-5347 Hetero dimer : IID00377Complex
 Evidence X-RAY 4erq D Reference
       Region 4erq D 5333-5345 order
       Region 4erq D 5346-5346 disorder
 Evidence X-RAY 4erq E Reference
       Region 4erq E 5333-5345 order
       Region 4erq E 5346-5346 disorder
 Evidence X-RAY 4erq F Reference
       Region 4erq F 5333-5345 order
       Region 4erq F 5346-5346 disorder
 Evidence X-RAY 3uvk B Reference
       Region 3uvk B 5337-5347 order
Seq 5382-5536 Monomer :
 Evidence X-RAY 4z4p A Reference
       Region 4z4p A 5382-5536 order
Seqphosphorylation
    27-27 Phosphoserine
    744-744 Phosphoserine
    1151-1151 Phosphoserine
    1195-1195 Phosphothreonine
    1249-1249 Phosphoserine
    1267-1267 Phosphothreonine
    1270-1270 Phosphoserine
    1606-1606 Phosphoserine
    1671-1671 Phosphoserine
    1820-1820 Phosphoserine
    1834-1834 Phosphoserine
    1843-1843 Phosphothreonine
    1865-1865 Phosphothreonine
    2239-2239 Phosphoserine
    2240-2240 Phosphothreonine
    2260-2260 Phosphoserine
    2274-2274 Phosphoserine
    2309-2309 Phosphoserine
    2311-2311 Phosphoserine
    2342-2342 Phosphoserine
    2640-2640 Phosphoserine
    3130-3130 Phosphoserine
    3197-3197 Phosphothreonine
    3199-3199 Phosphoserine
    4215-4215 Phosphoserine
    4359-4359 Phosphoserine
    4738-4738 Phosphoserine
    4822-4822 Phosphoserine
    4849-4849 Phosphoserine
Seqacetylation
    2246-2246 N6-acetyllysine
    3079-3079 N6-acetyllysine
    3433-3433 N6-acetyllysine
    4465-4465 N6-acetyllysine
    4776-4776 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-155,219-219,324-1379,1479-1494,1565-1999,2078-3031,3075-3406,3442-3500,3563-5030,5318-5386
Known Domain 156-218,220-323,1380-1478,1495-1564,2000-2077,3501-3562,5031-5136,5180-5317,5387-5537
Cryptic Domain 3032-3074,3407-3441,5137-5179
SCOPe RPS-Blast
     1fp0A1 229-281 1e-04 g.50.1.2 Death associated transcription factor ...
     4qf3A1 275-321 6e-15 g.50.1.0 automated matches
     1wevA1 1376-1427 4e-06 g.50.1.2 Death associated transcription fact...
     3zvzB1 1429-1474 9e-19 g.50.1.0 automated matches
     1we9A1 1507-1557 5e-05 g.50.1.2 Death associated transcription fact...
     2es4D1 3805-3955 2e-11 a.137.15.1 Lipase chaperone LifO (LipB)
     2f69A2 5382-5535 1e-44 b.85.7.1 Dim-5
SCOP Hmmer
     1mm3A_ 169-217 0.0009 FYVE/PHD zinc finger
     1wevA_ 215-274 2.8e-10 FYVE/PHD zinc finger
     1wevA_ 272-326 7.7e-15 FYVE/PHD zinc finger
     1wevA_ 1374-1428 8.3e-11 FYVE/PHD zinc finger
     1wevA_ 1420-1480 3.6e-16 FYVE/PHD zinc finger
     1wepA_ 1495-1564 8.7e-12 FYVE/PHD zinc finger
     1cg7A_ 2022-2072 2.5e-08 a.21.1.1 High mobility...
     1n6aA2 5379-5537 1.1e-50 b.85.7.1 Dim-5
Pfam RPS-Blast
     PF13771 139-218 4e-22 PHD-like zinc-binding domai...
     PF00628 229-274 2e-05 PHD-finger
     PF00628 276-321 6e-10 PHD-finger
     PF03154 427-822 5e-14 Atrophin-1 family
     PF00628 1379-1427 7e-07 PHD-finger
     PF00628 1430-1475 2e-10 PHD-finger
     PF00628 1507-1557 9e-04 PHD-finger
     PF03154 2180-2571 3e-06 Atrophin-1 family
     PF11169 3557-3636 4e-04 Protein of unknown functi...
     PF11498 3719-4008 1e-21 Transcriptional activator...
     PF03154 3988-4439 3e-05 Atrophin-1 family
     PF04929 4878-4986 3e-04 Herpes DNA replication ac...
     PF13771 5059-5137 1e-21 PHD-like zinc-binding dom...
     PF05964 5181-5232 6e-13 F/Y-rich N-terminus
     PF05965 5239-5322 5e-16 F/Y rich C-terminus
Pfam Hmmer
    PF13771 139-218 2.1e-12 PHD-like zinc-binding doma...
    PF00628 275-323 7.5e-13 PHD-finger
    PF00628 1379-1428 2.8e-11 PHD-finger
    PF00628 1429-1477 4.9e-13 PHD-finger
    PF13832 5031-5128 2.9e-12 PHD-zinc-finger like dom...
    PF05964 5181-5232 9.1e-23 F/Y-rich N-terminus
    PF05965 5238-5322 3.2e-29 F/Y rich C-terminus
    PF00856 5408-5512 1.5e-21 SET domain