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IID00389  Histone-lysine N-methyltransferase 2C (Homo sapiens) Q8NEZ4
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
4911
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 342-439 Monomer :
 Evidence NMR 2ysm A Reference
       Region 2ysm A 342-439 order
Seq 1631-1713 Monomer :
 Evidence NMR 2yuk A Reference
       Region 2yuk A 1631-1713 order
       Region 2yuk A 1631-1634 high_rmsd
       Region 2yuk A 1709-1713 high_rmsd
Seq 4703-4717 Hetero dimer : IID00377Complex
 Evidence X-RAY 4ery D Reference
       Region 4ery D 4703-4716 order
 Evidence X-RAY 3uvl B Reference
       Region 3uvl B 4707-4715 order
       Region 3uvl B 4716-4717 disorder
Seq 4757-4910 Monomer :
 Evidence X-RAY 5f59 A Reference
       Region 5f59 A 4757-4889 order
       Region 5f59 A 4890-4895 disorder
       Region 5f59 A 4896-4910 order
Seq 4757-4911 Hetero nonamer : IID00387Complex,Q6NXT2,Q9UBL3
 Evidence X-RAY 5f6k C Reference
       Region 5f6k C 4757-4888 order
       Region 5f6k C 4889-4896 disorder
       Region 5f6k C 4897-4911 order
 Evidence X-RAY 5f6k E Reference
       Region 5f6k E 4757-4886 order
       Region 5f6k E 4887-4895 disorder
       Region 5f6k E 4896-4911 order
Seq 4757-4911 Hetero pentamer : IID00387Complex,Q6NXT2,Q9UBL3
 Evidence X-RAY 5f6k C Reference
       Region 5f6k C 4757-4888 order
       Region 5f6k C 4889-4896 disorder
       Region 5f6k C 4897-4911 order
Seq 4757-4911 Hetero tetramer : IID00387Complex,Q9UBL3
 Evidence X-RAY 5f6k E Reference
       Region 5f6k E 4757-4886 order
       Region 5f6k E 4887-4895 disorder
       Region 5f6k E 4896-4911 order
Seqphosphorylation
    28-28 Phosphoserine
    46-46 Phosphoserine
    89-89 Phosphoserine
    113-113 Phosphoserine
    200-200 Phosphoserine
    854-854 Phosphoserine
    1301-1301 Phosphoserine
    1987-1987 Phosphoserine
    2828-2828 Phosphoserine
    3758-3758 Phosphoserine
    4034-4034 Phosphoserine
    4267-4267 Phosphoserine
Seqacetylation
    758-758 N6-acetyllysine
    1508-1508 N6-acetyllysine
    1772-1772 N6-acetyllysine
    2009-2009 N6-acetyllysine
    2802-2802 N6-acetyllysine
    2809-2809 N6-acetyllysine
    2832-2832 N6-acetyllysine
    2867-2867 N6-acetyllysine
    3714-3714 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-248,331-341,440-464,537-959,1058-1086,1143-1623,1714-1903,2363-2733,2776-4400,4688-4760
Known Domain 249-330,342-439,465-536,960-1057,1087-1142,1624-1713,1904-2362,4401-4498,4550-4687,4761-4911
Cryptic Domain 2734-2775,4499-4549
SCOPe RPS-Blast
     1fp0A1 340-396 1e-05 g.50.1.2 Death associated transcription factor ...
     3zvzB1 390-436 1e-13 g.50.1.0 automated matches
     1we9A1 467-518 3e-04 g.50.1.2 Death associated transcription factor...
     1wevA1 950-1008 1e-06 g.50.1.2 Death associated transcription facto...
     3zvzB1 1008-1054 5e-19 g.50.1.0 automated matches
     2mrcA 1654-1702 3e-04 a.21.1.0 automated matches
     2f69A2 4770-4898 3e-43 b.85.7.1 Dim-5
SCOP Hmmer
     1fp0A1 337-392 3.5e-11 g.50.1.2 Death associate...
     1wevA_ 381-443 1e-15 FYVE/PHD zinc finger
     1wevA_ 457-520 1.9e-09 FYVE/PHD zinc finger
     1wevA_ 950-1008 7.1e-13 FYVE/PHD zinc finger
     1wevA_ 1000-1061 1.9e-15 FYVE/PHD zinc finger
     1wepA_ 1074-1141 4.9e-12 FYVE/PHD zinc finger
     1cg7A_ 1655-1702 1.6e-07 a.21.1.1 High mobility...
     1n6aA2 4753-4911 1.9e-50 b.85.7.1 Dim-5
Pfam RPS-Blast
     PF13771 252-330 3e-22 PHD-like zinc-binding domai...
     PF00628 344-389 7e-06 PHD-finger
     PF00628 388-438 1e-08 PHD-finger
     PF00628 467-519 2e-05 PHD-finger
     PF00628 959-1008 5e-07 PHD-finger
     PF00628 1010-1057 3e-10 PHD-finger
     PF03154 1761-2228 2e-10 Atrophin-1 family
     PF12128 3177-3274 6e-05 Protein of unknown functi...
     PF09606 3269-3478 3e-04 ARC105 or Med15 subunit o...
     PF05110 3484-3917 1e-04 AF-4 proto-oncoprotein
     PF13771 4429-4507 1e-23 PHD-like zinc-binding dom...
     PF05964 4551-4602 3e-13 F/Y-rich N-terminus
     PF05965 4611-4692 1e-15 F/Y rich C-terminus
     PF00856 4782-4886 1e-04 SET domain
Pfam Hmmer
    PF13771 252-330 1.7e-11 PHD-like zinc-binding doma...
    PF00628 391-437 2.5e-12 PHD-finger
    PF00628 959-1010 1.9e-12 PHD-finger
    PF00628 1009-1055 2.8e-13 PHD-finger
    PF13832 4401-4496 8.7e-14 PHD-zinc-finger like dom...
    PF05964 4551-4602 1.5e-22 F/Y-rich N-terminus
    PF05965 4608-4692 4e-27 F/Y rich C-terminus
    PF00856 4782-4886 1.3e-21 SET domain