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IID00404  Menin (Homo sapiens) O00255
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
615
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-432,537-593 Hetero dimer :
 Evidence X-RAY 4x5y A Reference
       Region 4x5y A 1-1 disorder
       Region 4x5y A 2-432 order
       Region 4x5y A 537-541 order
       Region 4x5y A 542-553 disorder
       Region 4x5y A 554-593 order
Seq 1-432,537-598 Hetero dimer :
 Evidence X-RAY 4x5z A Reference
       Region 4x5z A 1-1 disorder
       Region 4x5z A 2-432 order
       Region 4x5z A 537-541 order
       Region 4x5z A 542-553 disorder
       Region 4x5z A 554-593 order
       Region 4x5z A 594-598 disorder
Seq 1-615 Monomer :
 Evidence X-RAY 6b41 A Reference
       Region 6b41 A 2-70 order
       Region 6b41 A 71-73 disorder
       Region 6b41 A 74-390 order
       Region 6b41 A 391-406 disorder
       Region 6b41 A 407-532 order
       Region 6b41 A 533-552 disorder
       Region 6b41 A 553-586 order
       Region 6b41 A 587-615 disorder
 Evidence X-RAY 5db0 A Reference
       Region 5db0 A 1-1 disorder
       Region 5db0 A 2-541 order
       Region 5db0 A 542-553 disorder
       Region 5db0 A 554-593 order
 Evidence X-RAY 5db1 A Reference
       Region 5db1 A 1-1 disorder
       Region 5db1 A 2-541 order
       Region 5db1 A 542-553 disorder
       Region 5db1 A 554-593 order
 Evidence X-RAY 5db2 A Reference
       Region 5db2 A 1-1 disorder
       Region 5db2 A 2-541 order
       Region 5db2 A 542-553 disorder
       Region 5db2 A 554-593 order
 Evidence X-RAY 5db3 A Reference
       Region 5db3 A 1-1 disorder
       Region 5db3 A 2-541 order
       Region 5db3 A 542-553 disorder
       Region 5db3 A 554-593 order
 Evidence X-RAY 5dd9 A Reference
       Region 5dd9 A 1-1 disorder
       Region 5dd9 A 2-541 order
       Region 5dd9 A 542-553 disorder
       Region 5dd9 A 554-593 order
       Region 5dd9 A 594-598 disorder
 Evidence X-RAY 5dda A Reference
       Region 5dda A 1-1 disorder
       Region 5dda A 2-541 order
       Region 5dda A 542-553 disorder
       Region 5dda A 554-592 order
       Region 5dda A 593-593 disorder
 Evidence X-RAY 5ddb A Reference
       Region 5ddb A 1-2 disorder
       Region 5ddb A 3-541 order
       Region 5ddb A 542-553 disorder
       Region 5ddb A 554-591 order
       Region 5ddb A 592-598 disorder
 Evidence X-RAY 5ddc A Reference
       Region 5ddc A 1-2 disorder
       Region 5ddc A 3-541 order
       Region 5ddc A 542-553 disorder
       Region 5ddc A 554-593 order
       Region 5ddc A 594-598 disorder
 Evidence X-RAY 5ddd A Reference
       Region 5ddd A 1-1 disorder
       Region 5ddd A 2-541 order
       Region 5ddd A 542-553 disorder
       Region 5ddd A 554-593 order
 Evidence X-RAY 5dde A Reference
       Region 5dde A 1-1 disorder
       Region 5dde A 2-541 order
       Region 5dde A 542-553 disorder
       Region 5dde A 554-593 order
 Evidence X-RAY 5ddf A Reference
       Region 5ddf A 1-1 disorder
       Region 5ddf A 2-541 order
       Region 5ddf A 542-553 disorder
       Region 5ddf A 554-591 order
       Region 5ddf A 592-593 disorder
 Evidence X-RAY 4gpq A Reference
       Region 4gpq A 1-1 disorder
       Region 4gpq A 2-541 order
       Region 4gpq A 542-553 disorder
       Region 4gpq A 554-594 order
       Region 4gpq A 595-598 disorder
 Evidence X-RAY 4gq3 A Reference
       Region 4gq3 A 1-1 disorder
       Region 4gq3 A 2-541 order
       Region 4gq3 A 542-553 disorder
       Region 4gq3 A 554-593 order
       Region 4gq3 A 594-598 disorder
 Evidence X-RAY 4gq4 A Reference
       Region 4gq4 A 1-1 disorder
       Region 4gq4 A 2-543 order
       Region 4gq4 A 544-553 disorder
       Region 4gq4 A 554-593 order
       Region 4gq4 A 594-598 disorder
 Evidence X-RAY 4og3 A Reference
       Region 4og3 A 1-1 disorder
       Region 4og3 A 2-543 order
       Region 4og3 A 544-544 disorder
       Region 4og3 A 545-591 order
       Region 4og3 A 592-598 disorder
 Evidence X-RAY 4og4 A Reference
       Region 4og4 A 1-1 disorder
       Region 4og4 A 2-593 order
       Region 4og4 A 594-598 disorder
 Evidence X-RAY 4og5 A Reference
       Region 4og5 A 1-1 disorder
       Region 4og5 A 2-593 order
       Region 4og5 A 594-598 disorder
 Evidence X-RAY 4og6 A Reference
       Region 4og6 A 1-1 disorder
       Region 4og6 A 2-543 order
       Region 4og6 A 544-553 disorder
       Region 4og6 A 554-593 order
       Region 4og6 A 594-598 disorder
 Evidence X-RAY 4og7 A Reference
       Region 4og7 A 1-1 disorder
       Region 4og7 A 2-543 order
       Region 4og7 A 544-552 disorder
       Region 4og7 A 553-592 order
       Region 4og7 A 593-598 disorder
 Evidence X-RAY 4og8 A Reference
       Region 4og8 A 1-1 disorder
       Region 4og8 A 2-543 order
       Region 4og8 A 544-552 disorder
       Region 4og8 A 553-593 order
       Region 4og8 A 594-598 disorder
 Evidence X-RAY 3u84 A Reference
       Region 3u84 A 2-391 order
       Region 3u84 A 392-406 disorder
       Region 3u84 A 407-533 order
       Region 3u84 A 534-538 disorder
       Region 3u84 A 539-544 order
       Region 3u84 A 545-552 disorder
       Region 3u84 A 553-586 order
       Region 3u84 A 587-600 disorder
       Region 3u84 A 601-613 order
       Region 3u84 A 614-615 disorder
 Evidence X-RAY 3u84 B Reference
       Region 3u84 B 2-70 order
       Region 3u84 B 71-74 disorder
       Region 3u84 B 75-204 order
       Region 3u84 B 205-210 disorder
       Region 3u84 B 211-390 order
       Region 3u84 B 391-406 disorder
       Region 3u84 B 407-524 order
       Region 3u84 B 525-527 disorder
       Region 3u84 B 528-533 order
       Region 3u84 B 534-552 disorder
       Region 3u84 B 553-586 order
       Region 3u84 B 587-615 disorder
Seq 1-615 Hetero dimer : IID00379Complex
 Evidence X-RAY 4gq6 A Reference
       Region 4gq6 A 1-1 disorder
       Region 4gq6 A 2-542 order
       Region 4gq6 A 543-553 disorder
       Region 4gq6 A 554-593 order
       Region 4gq6 A 594-598 disorder
 Evidence X-RAY 3u85 A Reference
       Region 3u85 A 2-390 order
       Region 3u85 A 391-406 disorder
       Region 3u85 A 407-532 order
       Region 3u85 A 533-552 disorder
       Region 3u85 A 553-586 order
       Region 3u85 A 587-615 disorder
Seq 2-615 Hetero dimer : IID00542Complex
 Evidence X-RAY 3u86 A Reference
       Region 3u86 A 2-390 order
       Region 3u86 A 391-406 disorder
       Region 3u86 A 407-532 order
       Region 3u86 A 533-552 disorder
       Region 3u86 A 553-586 order
       Region 3u86 A 587-615 disorder
Seq 2-615 Homo dimer :
 Evidence X-RAY 4i80 A Reference
       Region 4i80 A 2-390 order
       Region 4i80 A 391-406 disorder
       Region 4i80 A 407-532 order
       Region 4i80 A 533-552 disorder
       Region 4i80 A 553-586 order
       Region 4i80 A 587-615 disorder
Seq 2-615 Hetero trimer : IID00379Complex,IID00408Complex
 Evidence X-RAY 3u88 A Reference
       Region 3u88 A 2-70 order
       Region 3u88 A 71-72 disorder
       Region 3u88 A 73-390 order
       Region 3u88 A 391-406 disorder
       Region 3u88 A 407-524 order
       Region 3u88 A 525-551 disorder
       Region 3u88 A 552-588 order
       Region 3u88 A 589-615 disorder
 Evidence X-RAY 3u88 B Reference
       Region 3u88 B 2-391 order
       Region 3u88 B 392-404 disorder
       Region 3u88 B 405-525 order
       Region 3u88 B 526-548 disorder
       Region 3u88 B 549-587 order
       Region 3u88 B 588-615 disorder
Seqphosphorylation
    492-492 Phosphoserine
    548-548 Phosphoserine
    599-599 Phosphothreonine
 
Prediction
DICHOT
Disorder 1-1,465-615
Known Domain 2-464
SCOPe RPS-Blast
     4gq4A1 2-235 1e-81 d.389.1.1 Menin N-terminal domain
     4gq4A2 236-593 e-105 a.118.8.1 Bro1
Pfam RPS-Blast
     PF05053 538-589 7e-14 Menin
Pfam Hmmer
    PF05053 4-503 4.9e-254 Menin
    PF05053 553-613 1e-27 Menin