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IID00406  Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens) O43683
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1085
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-150 Hetero dimer : IID00417Complex
 Evidence X-RAY 4a1g A Reference
       Region 4a1g A 1-1 disorder
       Region 4a1g A 2-147 order
       Region 4a1g A 148-150 disorder
 Evidence X-RAY 4a1g B Reference
       Region 4a1g B 1-1 disorder
       Region 4a1g B 2-150 order
 Evidence X-RAY 4a1g C Reference
       Region 4a1g C 1-1 disorder
       Region 4a1g C 2-150 order
 Evidence X-RAY 4a1g D Reference
       Region 4a1g D 1-148 order
       Region 4a1g D 149-150 disorder
Seq 1-150 Monomer :
 Evidence NMR 2lah A Reference
       Region 2lah A 1-150 order
       Region 2lah A 150-150 high_rmsd
Seq 724-1085 Monomer :
 Evidence X-RAY 5dmz A Reference
       Region 5dmz A 726-734 disorder
       Region 5dmz A 735-806 order
       Region 5dmz A 807-815 disorder
       Region 5dmz A 816-1083 order
       Region 5dmz A 1084-1085 disorder
 Evidence X-RAY 5dmz B Reference
       Region 5dmz B 726-734 disorder
       Region 5dmz B 735-806 order
       Region 5dmz B 807-815 disorder
       Region 5dmz B 816-1083 order
       Region 5dmz B 1084-1085 disorder
 Evidence X-RAY 4qpm A Reference
       Region 4qpm A 740-806 order
       Region 4qpm A 807-814 disorder
       Region 4qpm A 815-931 order
       Region 4qpm A 932-938 disorder
       Region 4qpm A 939-1083 order
       Region 4qpm A 1084-1085 disorder
 Evidence X-RAY 4qpm B Reference
       Region 4qpm B 740-806 order
       Region 4qpm B 807-815 disorder
       Region 4qpm B 816-931 order
       Region 4qpm B 932-936 disorder
       Region 4qpm B 937-1081 order
       Region 4qpm B 1082-1085 disorder
 Evidence X-RAY 4r8q A Reference
       Region 4r8q A 724-735 disorder
       Region 4r8q A 736-806 order
       Region 4r8q A 807-815 disorder
       Region 4r8q A 816-931 order
       Region 4r8q A 932-938 disorder
       Region 4r8q A 939-1083 order
       Region 4r8q A 1084-1085 disorder
Seqphosphorylation
    307-307 Phosphoserine
    314-314 Phosphoserine
    331-331 Phosphoserine
    375-375 Phosphoserine
    525-525 Phosphoserine
    563-563 Phosphoserine
    593-593 Phosphoserine
    596-596 Phosphoserine
    609-609 Phosphothreonine; by CDK1
    655-655 Phosphoserine
    661-661 Phosphoserine
    668-668 Phosphoserine
    672-672 Phosphoserine
 
Prediction
DICHOT
Disorder 1-1,148-739,1084-1085
Known Domain 2-147,740-1083
SCOPe RPS-Blast
     3op5A 777-948 2e-14 d.144.1.0 automated matches
SCOP Hmmer
     1csnA_ 789-1061 3.6e-35 d.144.1.7 3-phosphoinos...
Pfam RPS-Blast
     PF08311 9-126 2e-32 Mad3/BUB1 homology region 1
Pfam Hmmer
    PF08311 9-126 5.1e-40 Mad3/BUB1 homology region 1
    PF00069 790-1004 8.6e-20 Protein kinase domain