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IID00420  Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Homo sapiens) Q96QZ7
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1491
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 295-338 Monomer :
 Evidence NMR 2ysd A Reference
       Region 2ysd A 295-338 order
       Region 2ysd A 295-296 high_rmsd
       Region 2ysd A 336-338 high_rmsd
Seq 355-401 Monomer :
 Evidence NMR 2yse A Reference
       Region 2yse A 355-401 order
 Evidence NMR 2zaj A Reference
       Region 2zaj A 355-390 order
Seq 454-558 Hetero pentamer : P07355,Q15418
 Evidence X-RAY 5n7f A Reference
       Region 5n7f A 454-455 disorder
       Region 5n7f A 456-558 order
 Evidence X-RAY 5n7f B Reference
       Region 5n7f B 454-458 disorder
       Region 5n7f B 459-556 order
       Region 5n7f B 557-558 disorder
Seq 455-558 Hetero pentamer : P07355,Q15418
 Evidence X-RAY 5n7d A Reference
       Region 5n7d A 455-455 disorder
       Region 5n7d A 456-558 order
 Evidence X-RAY 5n7d B Reference
       Region 5n7d B 455-458 disorder
       Region 5n7d B 459-558 order
Seqdisorder 455-558
 Evidence X-RAY 5n7g B Reference
       Region 5n7g B 455-558 disorder
Seq 455-558 Hetero pentamer : P07355,Q15418
 Evidence X-RAY 5n7g A Reference
       Region 5n7g A 455-455 disorder
       Region 5n7g A 456-558 order
Seq 455-580 Hetero dimer : IID90005Complex
 Evidence NMR 2kpl A Reference
       Region 2kpl A 455-580 order
       Region 2kpl A 455-455 high_rmsd
       Region 2kpl A 565-580 high_rmsd
Seq 455-580 Monomer :
 Evidence NMR 2kpk A Reference
       Region 2kpk A 455-580 order
       Region 2kpk A 562-580 high_rmsd
Seq 640-721 Monomer :
 Evidence X-RAY 3bpu A Reference
       Region 3bpu A 640-673 order
       Region 3bpu A 674-675 disorder
       Region 3bpu A 676-721 order
Seq 839-922 Monomer :
 Evidence X-RAY 2q9v A Reference
       Region 2q9v A 839-922 order
Seq 1149-1233 Monomer :
 Evidence X-RAY 2r4h A Reference
       Region 2r4h A 1149-1233 order
 Evidence X-RAY 2r4h B Reference
       Region 2r4h B 1149-1233 order
 Evidence X-RAY 2r4h C Reference
       Region 2r4h C 1149-1233 order
Seqphosphorylation
    357-357 Phosphoserine
    730-730 Phosphoserine
    741-741 Phosphoserine
    800-800 Phosphoserine
    1071-1071 Phosphoserine
    1361-1361 Phosphoserine
    1412-1412 Phosphoserine
 
Prediction
DICHOT
Disorder 1-8,112-121,193-293,402-454,581-639,722-838,924-994,1096-1148,1238-1491
Known Domain 9-111,122-192,294-401,455-580,640-721,839-923,995-1095,1149-1237
SCOPe RPS-Blast
     2gzvA1 19-99 6e-06 b.36.1.0 automated matches
     1kgdA 116-191 1e-16 c.37.1.1 5' polynucleotide kinase-3' phosphatase...
     4rexA1 298-332 3e-16 b.72.1.1 Amyloid beta A4 precursor protein-bin...
     2itkA1 361-390 6e-07 b.72.1.1 Amyloid beta A4 precursor protein-bin...
     1ueqA1 458-568 3e-50 b.36.1.1 Afadin
     3bpuA1 640-721 3e-36 b.36.1.0 automated matches
     2q9vA1 839-922 1e-34 b.36.1.0 automated matches
     1uewA1 994-1098 9e-38 b.36.1.1 Afadin
     2r4hA1 1149-1233 3e-36 b.36.1.0 automated matches
SCOP Hmmer
     2cs5A1 9-111 8.1e-13 b.36.1.1 Afadin
     1vyuA2 129-260 4.6e-19 c.37.1.1 5' polynucleoti...
     1i5hW_ 295-335 3.2e-15 b.72.1.1 Amyloid beta A4...
     1tk7A1 352-391 3e-11 b.72.1.1 Amyloid beta A4 p...
     1wifA_ 454-561 5.3e-25 PDZ domain-like
     1wifA_ 619-731 1.2e-23 PDZ domain-like
     1wifA_ 828-926 4.4e-24 PDZ domain-like
     1wfgA_ 992-1094 2e-26 PDZ domain-like
     1i16A_ 1141-1237 7.6e-27 b.36.1.2 Interleukin 1...
Pfam RPS-Blast
     PF16663 202-261 2e-11 Unstructured region on MAGI
     PF00397 302-331 3e-08 WW domain
     PF00397 361-390 1e-04 WW domain
     PF10956 383-439 8e-04 Protein of unknown function...
     PF17820 498-554 3e-08 PDZ domain
     PF17820 667-721 7e-08 PDZ domain
     PF16666 722-811 1e-27 Unstructured region on MAGI
     PF17820 866-923 9e-10 PDZ domain
     PF17820 1038-1090 3e-12 PDZ domain
     PF17820 1177-1232 3e-09 PDZ domain
     PF17069 1350-1480 2e-07 Arginine/Serine-Rich prot...
Pfam Hmmer
    PF00625 139-190 8.8e-14 Guanylate kinase
    PF16663 202-261 5.1e-33 Unstructured region on MAG...
    PF00397 302-331 3.9e-13 WW domain
    PF00397 361-390 6.2e-10 WW domain
    PF00595 475-541 1.4e-12 PDZ domain
    PF00595 644-720 3.3e-12 PDZ domain
    PF16666 723-840 2.2e-48 Unstructured region on MAG...
    PF00595 847-921 9e-14 PDZ domain
    PF00595 999-1090 2.6e-17 PDZ domain
    PF00595 1153-1228 9.6e-17 PDZ domain