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IID00435  Nuclear factor of activated T-cells, cytoplasmic 1 (Homo sapiens) O95644
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
943
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 384-400 Hetero trimer : IID00060Complex,IID00069Complex
 Evidence X-RAY 5sve C Reference
       Region 5sve C 384-390 order
       Region 5sve C 391-400 disorder
Seq 414-591 Monomer :
 Evidence NMR 1a66 A Reference
       Region 1a66 A 414-591 order
       Region 1a66 A 414-421 high_rmsd
       Region 1a66 A 454-456 high_rmsd
       Region 1a66 A 591-591 high_rmsd
 Evidence NMR 1nfa A Reference
       Region 1nfa A 416-427 order
       Region 1nfa A 416-424 high_rmsd
       Region 1nfa A 428-440 disorder
       Region 1nfa A 441-448 order
       Region 1nfa A 443-448 high_rmsd
       Region 1nfa A 449-464 disorder
       Region 1nfa A 465-533 order
       Region 1nfa A 534-568 disorder
       Region 1nfa A 540-555 high_rmsd
       Region 1nfa A 569-591 order
       Region 1nfa A 588-591 high_rmsd
SeqProS verified 414-591 This region is ordered when it binds upon DNA. :
       Region 1a66 A 414-591 order
       Region 1nfa A 428-440 disorder
       Region 1nfa A 449-464 disorder
       Region 1nfa A 534-568 disorder
Seqphosphorylation
    233-233 Phosphoserine
    237-237 Phosphoserine
    245-245 Phosphoserine; by PKA
    269-269 Phosphoserine; by PKA
    294-294 Phosphoserine; by PKA
 
Prediction
DICHOT
Disorder 1-416,697-943
Known Domain 417-696
SCOPe RPS-Blast
     2as5M2 415-593 2e-66 b.2.5.3 Dorsal homologue Gambif1
     2as5M1 594-696 5e-26 b.1.18.1 Calmodulin binding transcription acti...
SCOP Hmmer
     1a02N2 417-593 1.6e-77 b.2.5.3 Dorsal homologue...
     1oy3C_ 594-715 1.2e-34 b.1.18.1 Calmodulin bind...
Pfam RPS-Blast
     PF00554 428-588 4e-38 Rel homology DNA-binding do...
     PF16179 598-695 4e-24 Rel homology dimerisation d...
Pfam Hmmer
    PF00554 428-588 2.2e-28 Rel homology DNA-binding d...
    PF16179 598-696 2.7e-27 Rel homology dimerisation ...