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IID00440  Heat shock cognate 71 kDa protein (Homo sapiens) P11142
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
646
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-381 Hetero hexamer : IID00495Complex
 Evidence X-RAY 5aqo A Reference
       Region 5aqo A 1-381 order
 Evidence X-RAY 5aqo C Reference
       Region 5aqo C 1-381 order
 Evidence X-RAY 5aqo E Reference
       Region 5aqo E 1-381 order
Seq 1-381 Hetero hexamer : IID00495Complex
 Evidence X-RAY 5aqn A Reference
       Region 5aqn A 1-381 order
 Evidence X-RAY 5aqn C Reference
       Region 5aqn C 1-381 order
 Evidence X-RAY 5aqn E Reference
       Region 5aqn E 1-381 order
Seq 1-381 Hetero dimer : IID00495Complex
 Evidence X-RAY 5aqf A Reference
       Region 5aqf A 1-381 order
 Evidence X-RAY 5aqf C Reference
       Region 5aqf C 1-381 order
 Evidence X-RAY 5aqg A Reference
       Region 5aqg A 1-381 order
 Evidence X-RAY 5aqg C Reference
       Region 5aqg C 1-381 order
 Evidence X-RAY 5aqg E Reference
       Region 5aqg E 1-380 order
       Region 5aqg E 381-381 disorder
 Evidence X-RAY 5aqh A Reference
       Region 5aqh A 1-381 order
 Evidence X-RAY 5aqi A Reference
       Region 5aqi A 1-381 order
 Evidence X-RAY 5aqi C Reference
       Region 5aqi C 1-381 order
 Evidence X-RAY 5aqj E Reference
       Region 5aqj E 1-381 order
 Evidence X-RAY 5aqj A Reference
       Region 5aqj A 1-381 order
 Evidence X-RAY 5aqj C Reference
       Region 5aqj C 1-381 order
 Evidence X-RAY 5aqk A Reference
       Region 5aqk A 1-3 disorder
       Region 5aqk A 4-381 order
 Evidence X-RAY 5aql A Reference
       Region 5aql A 1-381 order
 Evidence X-RAY 5aql C Reference
       Region 5aql C 1-381 order
 Evidence X-RAY 5aqm A Reference
       Region 5aqm A 1-381 order
 Evidence X-RAY 5aqm C Reference
       Region 5aqm C 1-381 order
 Evidence X-RAY 5aqp C Reference
       Region 5aqp C 1-381 order
 Evidence X-RAY 5aqp E Reference
       Region 5aqp E 1-381 order
 Evidence X-RAY 5aqp A Reference
       Region 5aqp A 1-381 order
 Evidence X-RAY 5aqq E Reference
       Region 5aqq E 1-381 order
 Evidence X-RAY 5aqq A Reference
       Region 5aqq A 1-381 order
 Evidence X-RAY 5aqq C Reference
       Region 5aqq C 1-381 order
 Evidence X-RAY 5aqr A Reference
       Region 5aqr A 1-381 order
 Evidence X-RAY 5aqr C Reference
       Region 5aqr C 1-381 order
 Evidence X-RAY 5aqr E Reference
       Region 5aqr E 1-381 order
 Evidence X-RAY 5aqs C Reference
       Region 5aqs C 1-3 disorder
       Region 5aqs C 4-381 order
 Evidence X-RAY 5aqs A Reference
       Region 5aqs A 1-381 order
 Evidence X-RAY 5aqt A Reference
       Region 5aqt A 1-380 order
       Region 5aqt A 381-381 disorder
 Evidence X-RAY 5aqu A Reference
       Region 5aqu A 1-381 order
 Evidence X-RAY 5aqv A Reference
       Region 5aqv A 1-3 disorder
       Region 5aqv A 4-381 order
 Evidence X-RAY 3fzk A Reference
       Region 3fzk A 4-4 disorder
       Region 3fzk A 5-381 order
 Evidence X-RAY 3fzm A Reference
       Region 3fzm A 4-4 disorder
       Region 3fzm A 5-381 order
 Evidence X-RAY 3ldq A Reference
       Region 3ldq A 4-4 disorder
       Region 3ldq A 5-381 order
 Evidence X-RAY 3m3z A Reference
       Region 3m3z A 4-4 disorder
       Region 3m3z A 5-381 order
 Evidence X-RAY 3fzf A Reference
       Region 3fzf A 4-4 disorder
       Region 3fzf A 5-381 order
 Evidence X-RAY 3fzh A Reference
       Region 3fzh A 4-4 disorder
       Region 3fzh A 5-381 order
 Evidence X-RAY 3fzl A Reference
       Region 3fzl A 4-4 disorder
       Region 3fzl A 5-381 order
Seq 2-384 Monomer :
 Evidence X-RAY 6b1i A Reference
       Region 6b1i A 5-381 order
 Evidence X-RAY 6b1i B Reference
       Region 6b1i B 5-381 order
 Evidence X-RAY 6b1m B Reference
       Region 6b1m B 5-381 order
 Evidence X-RAY 6b1m A Reference
       Region 6b1m A 5-381 order
 Evidence X-RAY 6b1n A Reference
       Region 6b1n A 5-188 order
       Region 6b1n A 189-189 disorder
       Region 6b1n A 190-381 order
 Evidence X-RAY 6b1n B Reference
       Region 6b1n B 5-381 order
 Evidence X-RAY 4h5n A Reference
       Region 4h5n A 2-2 disorder
       Region 4h5n A 3-384 order
 Evidence X-RAY 4h5n B Reference
       Region 4h5n B 2-2 disorder
       Region 4h5n B 3-384 order
 Evidence X-RAY 4h5r A Reference
       Region 4h5r A 2-2 disorder
       Region 4h5r A 3-384 order
 Evidence X-RAY 4h5r B Reference
       Region 4h5r B 2-2 disorder
       Region 4h5r B 3-384 order
 Evidence X-RAY 4h5t A Reference
       Region 4h5t A 2-2 disorder
       Region 4h5t A 3-384 order
 Evidence X-RAY 4h5v A Reference
       Region 4h5v A 2-2 disorder
       Region 4h5v A 3-384 order
 Evidence X-RAY 4h5w A Reference
       Region 4h5w A 2-2 disorder
       Region 4h5w A 3-384 order
 Evidence X-RAY 4h5w B Reference
       Region 4h5w B 2-2 disorder
       Region 4h5w B 3-384 order
Seq 5-381 Hetero dimer : IID50190Complex
 Evidence X-RAY 4hwi A Reference
       Region 4hwi A 5-5 disorder
       Region 4hwi A 6-381 order
Seq 541-646 Hetero dimer : Q9UNE7
 Evidence X-RAY 4kbq C Reference
       Region 4kbq C 541-618 order
       Region 4kbq C 619-625 disorder
       Region 4kbq C 626-638 order
       Region 4kbq C 639-639 disorder
       Region 4kbq C 640-646 order
 Evidence X-RAY 4kbq D Reference
       Region 4kbq D 541-557 order
       Region 4kbq D 558-560 disorder
       Region 4kbq D 561-587 order
       Region 4kbq D 588-590 disorder
       Region 4kbq D 591-620 order
       Region 4kbq D 621-625 disorder
       Region 4kbq D 626-638 order
       Region 4kbq D 639-639 disorder
       Region 4kbq D 640-646 order
Seqdisorder 616-636
 Evidence The region 616-636 is described to be disordered in the free state (PubMed=23865999). Reference
       Region 616-636 disorder
Seq 635-646 Hetero dimer : IID00449Complex
 Evidence X-RAY 3esk B Reference
       Region 3esk B 635-638 disorder
       Region 3esk B 639-646 order
Seq 639-646 Hetero pentamer : IID00446Complex
 Evidence X-RAY 3agy C Reference
       Region 3agy C 639-645 order
       Region 3agy C 646-646 disorder
 Evidence X-RAY 3agy D Reference
       Region 3agy D 639-646 order
 Evidence X-RAY 3agy F Reference
       Region 3agy F 639-639 disorder
       Region 3agy F 640-645 order
       Region 3agy F 646-646 disorder
Seq 639-646 Hetero hexamer : IID00446Complex
 Evidence X-RAY 3agz C Reference
       Region 3agz C 639-646 order
 Evidence X-RAY 3agz D Reference
       Region 3agz D 639-646 order
 Evidence X-RAY 3agz E Reference
       Region 3agz E 639-646 order
 Evidence X-RAY 3agz F Reference
       Region 3agz F 639-646 order
SeqProS possible 639-646 Same region of rat homolog (P63018, 99%identity) is disordered in the free state. Hetero dimer : IID00449Complex
       Region 3esk B 639-646 order
SeqProS possible 639-646 Same region of rat homolog (P63018, 99%identity) is disordered in the free state. Hetero hexamer : IID00446Complex
       Region 3agz C 639-646 order
       Region 3agz D 639-646 order
       Region 3agz E 639-646 order
       Region 3agz F 639-646 order
SeqProS possible 639-646 Same region of rat homolog (P63018, 99%identity) is disordered in the free state. Hetero pentamer : IID00446Complex
       Region 3agy C 639-645 order
       Region 3agy D 639-646 order
       Region 3agy F 640-645 order
SeqProS possible 640-646 Same region of rat homolog (P63018, 99%identity) is disordered in the free state. Hetero dimer : Q9UNE7
       Region 4kbq C 640-646 order
       Region 4kbq D 640-646 order
Seqphosphorylation
    153-153 Phosphoserine
    329-329 Phosphoserine
    362-362 Phosphoserine
    541-541 Phosphoserine
Seqacetylation
    2-2 N-acetylserine
    108-108 N6-acetyllysine
    246-246 N6-acetyllysine
    319-319 N6-acetyllysine; alternate
    328-328 N6-acetyllysine
    512-512 N6-acetyllysine; alternate
    524-524 N6-acetyllysine
    589-589 N6-acetyllysine
    597-597 N6-acetyllysine
    601-601 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-3,613-646
Known Domain 4-612
SCOPe RPS-Blast
     3i33A1 5-188 e-117 c.55.1.1 Actin
     3i33A2 188-380 e-115 c.55.1.1 Actin
     4f01A1 391-508 1e-75 b.130.1.1 Chaperone protein hscA (Hsc66)
     3lofA1 534-613 4e-28 a.8.4.0 automated matches
SCOP Hmmer
     1hjoA1 5-187 3.9e-76 c.55.1.1 Actin
     1hjoA2 192-382 7.6e-73 c.55.1.1 Actin
     1ckrA_ 386-543 1.7e-68 b.130.1.1 Chaperone prot...
     1ud0A_ 538-619 1.9e-34 Heat shock protein 70kD...
Pfam RPS-Blast
     PF06406 160-339 7e-05 StbA protein
Pfam Hmmer
    PF00012 6-612 4.4e-268 Hsp70 protein