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IID00451  RNA-binding protein FUS (Homo sapiens) P35637
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
526
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2-214 Homo nonamer :
 Evidence NMR 5w3n A Reference
       Region 5w3n A 2-36 disorder
       Region 5w3n A 37-97 order
       Region 5w3n A 37-40 high_rmsd
       Region 5w3n A 56-59 high_rmsd
       Region 5w3n A 98-214 disorder
 Evidence NMR 5w3n B Reference
       Region 5w3n B 2-36 disorder
       Region 5w3n B 37-97 order
       Region 5w3n B 37-40 high_rmsd
       Region 5w3n B 56-59 high_rmsd
       Region 5w3n B 98-214 disorder
 Evidence NMR 5w3n C Reference
       Region 5w3n C 2-36 disorder
       Region 5w3n C 37-97 order
       Region 5w3n C 37-41 high_rmsd
       Region 5w3n C 56-59 high_rmsd
       Region 5w3n C 98-214 disorder
 Evidence NMR 5w3n D Reference
       Region 5w3n D 2-36 disorder
       Region 5w3n D 37-97 order
       Region 5w3n D 37-41 high_rmsd
       Region 5w3n D 56-59 high_rmsd
       Region 5w3n D 98-214 disorder
 Evidence NMR 5w3n E Reference
       Region 5w3n E 2-36 disorder
       Region 5w3n E 37-97 order
       Region 5w3n E 37-41 high_rmsd
       Region 5w3n E 56-59 high_rmsd
       Region 5w3n E 98-214 disorder
 Evidence NMR 5w3n F Reference
       Region 5w3n F 2-36 disorder
       Region 5w3n F 37-97 order
       Region 5w3n F 37-41 high_rmsd
       Region 5w3n F 56-59 high_rmsd
       Region 5w3n F 98-214 disorder
 Evidence NMR 5w3n G Reference
       Region 5w3n G 2-36 disorder
       Region 5w3n G 37-97 order
       Region 5w3n G 37-41 high_rmsd
       Region 5w3n G 56-59 high_rmsd
       Region 5w3n G 98-214 disorder
 Evidence NMR 5w3n H Reference
       Region 5w3n H 2-36 disorder
       Region 5w3n H 37-97 order
       Region 5w3n H 37-41 high_rmsd
       Region 5w3n H 56-59 high_rmsd
       Region 5w3n H 98-214 disorder
 Evidence NMR 5w3n I Reference
       Region 5w3n I 2-36 disorder
       Region 5w3n I 37-97 order
       Region 5w3n I 37-41 high_rmsd
       Region 5w3n I 56-59 high_rmsd
       Region 5w3n I 98-214 disorder
Seq 278-385 Monomer :
 Evidence NMR 2la6 A Reference
       Region 2la6 A 282-370 order
       Region 2la6 A 282-282 high_rmsd
 Evidence NMR 2lcw A Reference
       Region 2lcw A 278-385 order
       Region 2lcw A 278-281 high_rmsd
       Region 2lcw A 328-329 high_rmsd
       Region 2lcw A 371-385 high_rmsd
Seq 495-526 Hetero dimer : IID00094Complex
 Evidence X-RAY 4fq3 B Reference
       Region 4fq3 B 495-507 disorder
       Region 4fq3 B 508-526 order
Seq 498-526 Hetero trimer : IID00094Complex
 Evidence X-RAY 4fdd B Reference
       Region 4fdd B 498-506 disorder
       Region 4fdd B 507-526 order
SeqProS possible 521-526 Nuclear Localization Signal (NLS) Hetero trimer : IID00094Complex
       Region 4fdd B 507-526 order
Seqphosphorylation
    221-221 Phosphoserine
    277-277 Phosphoserine
    286-286 Phosphothreonine
    340-340 Phosphoserine
 
Prediction
DICHOT
Disorder 1-274,371-425,450-526
Known Domain 275-370,426-449
SCOPe RPS-Blast
     2la6A1 282-370 2e-36 d.58.7.0 automated matches
     1n0zA1 416-452 4e-14 g.41.11.1 MDM2
SCOP Hmmer
     1u6fA1 273-386 7.5e-24 d.58.7.1 Alkylation repa...
     1n0zA_ 415-454 1.3e-14 Ran binding protein zin...
Pfam RPS-Blast
     PF18296 24-197 8e-05 MID domain of medPIWI
     PF00641 423-452 4e-09 Zn-finger in Ran binding pr...
Pfam Hmmer
    PF00076 287-365 1.4e-14 RNA recognition motif. (a....
    PF00641 422-453 3.9e-16 Zn-finger in Ran binding p...