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IID00455  Dual specificity mitogen-activated protein kinase kinase 6 (Homo sapiens) P52564
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
334
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-334 Monomer :
 Evidence X-RAY 3fme A Reference
       Region 3fme A 47-85 order
       Region 3fme A 86-88 disorder
       Region 3fme A 89-198 order
       Region 3fme A 199-213 disorder
       Region 3fme A 214-231 order
       Region 3fme A 232-233 disorder
       Region 3fme A 234-333 order
       Region 3fme A 334-334 disorder
 Evidence X-RAY 3vn9 A Reference
       Region 3vn9 A 1-43 disorder
       Region 3vn9 A 44-334 order
Seq 4-17 Hetero dimer : IID00280Complex
 Evidence X-RAY 2y8o B Reference
       Region 2y8o B 4-9 disorder
       Region 2y8o B 10-17 order
 Evidence X-RAY 5etf B Reference
       Region 5etf B 4-8 disorder
       Region 5etf B 9-16 order
       Region 5etf B 17-17 disorder
Seq 45-332 Homo dimer :
 Evidence X-RAY 3enm A Reference
       Region 3enm A 45-45 disorder
       Region 3enm A 46-207 order
       Region 3enm A 208-216 disorder
       Region 3enm A 217-332 order
 Evidence X-RAY 3enm C Reference
       Region 3enm C 45-47 disorder
       Region 3enm C 48-208 order
       Region 3enm C 209-216 disorder
       Region 3enm C 217-231 order
       Region 3enm C 232-234 disorder
       Region 3enm C 235-332 order
 Evidence X-RAY 3enm B Reference
       Region 3enm B 45-48 disorder
       Region 3enm B 49-53 order
       Region 3enm B 54-56 disorder
       Region 3enm B 57-208 order
       Region 3enm B 209-216 disorder
       Region 3enm B 217-232 order
       Region 3enm B 233-234 disorder
       Region 3enm B 235-332 order
 Evidence X-RAY 3enm D Reference
       Region 3enm D 45-207 order
       Region 3enm D 208-216 disorder
       Region 3enm D 217-332 order
SeqProS verified 9-17 Hetero dimer : IID00280Complex
       Region 2y8o B 10-17 order
       Region 5etf B 9-16 order
       Region 3vn9 A 1-43 disorder
Seqphosphorylation
    207-207 Phosphoserine; by MAP3K; alternate
    211-211 Phosphothreonine; by MAP3K; alternate
Seqacetylation
    207-207 O-acetylserine; by Yersinia yopJ; alternate
    211-211 O-acetylthreonine; by Yersinia yopJ; alternate
 
Prediction
DICHOT
Disorder 1-45,333-334
Known Domain 46-332
SCOPe RPS-Blast
     3enmA1 46-332 e-138 d.144.1.0 automated matches
SCOP Hmmer
     1kobA_ 41-315 2e-70 d.144.1.7 3-phosphoinositid...
Pfam RPS-Blast
     PF14531 171-260 1e-05 Kinase-like
Pfam Hmmer
    PF00069 56-314 5.1e-60 Protein kinase domain