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IID00470  Nuclear factor of activated T-cells, cytoplasmic 2 (Homo sapiens) Q13469
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
925
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 392-678 Hetero dimer : IID00429Complex
 Evidence X-RAY 2as5 N Reference
       Region 2as5 N 392-678 order
 Evidence X-RAY 2as5 M Reference
       Region 2as5 M 392-678 order
Seq 392-678 Hetero trimer : IID00436Complex,IID00437Complex
 Evidence X-RAY 1a02 N Reference
       Region 1a02 N 392-398 disorder
       Region 1a02 N 399-678 order
 Evidence X-RAY 1s9k C Reference
       Region 1s9k C 399-678 order
Seq 393-678 Homo dimer :
 Evidence X-RAY 1p7h L Reference
       Region 1p7h L 393-678 order
 Evidence X-RAY 1p7h M Reference
       Region 1p7h M 393-678 order
 Evidence X-RAY 1p7h N Reference
       Region 1p7h N 393-678 order
 Evidence X-RAY 1p7h O Reference
       Region 1p7h O 393-678 order
 Evidence X-RAY 1pzu B Reference
       Region 1pzu B 396-398 disorder
       Region 1pzu B 399-571 order
       Region 1pzu B 572-575 disorder
       Region 1pzu B 576-678 order
 Evidence X-RAY 1pzu D Reference
       Region 1pzu D 396-398 disorder
       Region 1pzu D 399-571 order
       Region 1pzu D 572-575 disorder
       Region 1pzu D 576-678 order
 Evidence X-RAY 1pzu H Reference
       Region 1pzu H 396-398 disorder
       Region 1pzu H 399-571 order
       Region 1pzu H 572-575 disorder
       Region 1pzu H 576-678 order
 Evidence X-RAY 1pzu I Reference
       Region 1pzu I 396-398 disorder
       Region 1pzu I 399-571 order
       Region 1pzu I 572-575 disorder
       Region 1pzu I 576-678 order
 Evidence X-RAY 1pzu L Reference
       Region 1pzu L 396-398 disorder
       Region 1pzu L 399-571 order
       Region 1pzu L 572-575 disorder
       Region 1pzu L 576-678 order
 Evidence X-RAY 1pzu M Reference
       Region 1pzu M 396-398 disorder
       Region 1pzu M 399-571 order
       Region 1pzu M 572-575 disorder
       Region 1pzu M 576-678 order
Seq 396-678 Homo trimer :
 Evidence X-RAY 2o93 L Reference
       Region 2o93 L 396-678 order
 Evidence X-RAY 2o93 M Reference
       Region 2o93 M 396-678 order
 Evidence X-RAY 2o93 O Reference
       Region 2o93 O 396-678 order
Seq 396-678 Monomer :
 Evidence X-RAY 1owr M Reference
       Region 1owr M 396-678 order
 Evidence X-RAY 1owr N Reference
       Region 1owr N 396-678 order
 Evidence X-RAY 1owr P Reference
       Region 1owr P 396-678 order
 Evidence X-RAY 1owr Q Reference
       Region 1owr Q 396-678 order
Seq 396-678 Hetero trimer : IID00497Complex
 Evidence X-RAY 3qrf N Reference
       Region 3qrf N 396-678 order
 Evidence X-RAY 3qrf M Reference
       Region 3qrf M 396-678 order
SeqProS possible 410-422,431-446,516-550 Same region of homolog (O95644, 84% identity) is disordered in the free state. Hetero dimer : IID00429Complex
       Region 2as5 M 392-678 order
       Region 2as5 N 392-678 order
SeqProS possible 410-422,431-446,516-550 Same region of homolog (O95644, 84% identity) is disordered in the free state. Hetero trimer : IID00497Complex
       Region 3qrf M 396-678 order
       Region 3qrf N 396-678 order
SeqProS possible 410-422,431-446,516-550 Same region of homolog (O95644, 84% identity) is disordered in the free state. Homo dimer :
       Region 1pzu B 399-571 order
       Region 1pzu D 399-571 order
       Region 1pzu H 399-571 order
       Region 1pzu I 399-571 order
       Region 1pzu L 399-571 order
       Region 1pzu M 399-571 order
       Region 1p7h L 393-678 order
       Region 1p7h M 393-678 order
       Region 1p7h N 393-678 order
       Region 1p7h O 393-678 order
SeqProS possible 410-422,431-446,516-550 Same region of homolog (O95644, 84% identity) is disordered in the free state. :
       Region 1owr M 396-678 order
       Region 1owr N 396-678 order
       Region 1owr P 396-678 order
       Region 1owr Q 396-678 order
SeqProS possible 410-422,431-446,516-550 Same region of homolog (O95644, 84% identity) is disordered in the free state. Homo trimer :
       Region 2o93 L 396-678 order
       Region 2o93 M 396-678 order
       Region 2o93 O 396-678 order
SeqProS possible 410-422,431-446,516-550 Same region of homolog (O95644, 84% identity) is disordered in the free state. Hetero trimer : IID00436Complex,IID00437Complex
       Region 1a02 N 399-678 order
       Region 1s9k C 399-678 order
Seqphosphorylation
    23-23 Phosphoserine
    99-99 Phosphoserine
    107-107 Phosphoserine
    110-110 Phosphoserine
    148-148 Phosphoserine
    213-213 Phosphoserine
    217-217 Phosphoserine
    221-221 Phosphoserine
    236-236 Phosphoserine
    243-243 Phosphoserine
    255-255 Phosphoserine
    268-268 Phosphoserine
    274-274 Phosphoserine
    276-276 Phosphoserine
    280-280 Phosphoserine
    326-326 Phosphoserine
    330-330 Phosphoserine
    363-363 Phosphoserine
    755-755 Phosphoserine
    757-757 Phosphoserine
    759-759 Phosphoserine
    856-856 Phosphoserine
    859-859 Phosphoserine
 
Prediction
DICHOT
Disorder 1-398,679-925
Known Domain 399-678
SCOPe RPS-Blast
     2as5M2 396-575 9e-68 b.2.5.3 Dorsal homologue Gambif1
     2as5M1 576-678 6e-28 b.1.18.1 Calmodulin binding transcription acti...
SCOP Hmmer
     1a02N2 399-575 5.4e-78 b.2.5.3 Dorsal homologue...
     1a02N1 577-677 5.9e-35 b.1.18.1 Calmodulin bind...
Pfam RPS-Blast
     PF00554 410-570 6e-39 Rel homology DNA-binding do...
     PF16179 580-677 5e-23 Rel homology dimerisation d...
Pfam Hmmer
    PF00554 410-570 7.5e-26 Rel homology DNA-binding d...
    PF16179 580-677 3.7e-29 Rel homology dimerisation ...