Search Keyword:


Search option:


IID00496  Histone-lysine N-methyltransferase NSD3 (Homo sapiens) Q9BZ95
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1437
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 152-163 Hetero dimer : IID00111Complex
 Evidence NMR 2ncz B Reference
       Region 2ncz B 152-163 order
       Region 2ncz B 163-163 high_rmsd
Seq 593-605 Hetero dimer : IID00111Complex
 Evidence NMR 2nd1 B Reference
       Region 2nd1 B 593-605 order
       Region 2nd1 B 605-605 high_rmsd
Seq 953-1064 Monomer :
 Evidence NMR 2daq A Reference
       Region 2daq A 957-1053 order
       Region 2daq A 1029-1033 high_rmsd
 Evidence X-RAY 4rxj A Reference
       Region 4rxj A 953-956 disorder
       Region 4rxj A 957-1064 order
Seq 1054-1285 Monomer :
 Evidence X-RAY 5upd A Reference
       Region 5upd A 1054-1068 disorder
       Region 5upd A 1069-1263 order
       Region 5upd A 1264-1266 disorder
       Region 5upd A 1267-1285 order
Seq 1310-1413 Monomer :
 Evidence X-RAY 4gnd A Reference
       Region 4gnd A 1310-1315 disorder
       Region 4gnd A 1316-1413 order
 Evidence X-RAY 4gnd C Reference
       Region 4gnd C 1310-1413 order
Seq 1310-1413 Hetero dimer : IID00239Complex
 Evidence X-RAY 4gne A Reference
       Region 4gne A 1310-1315 disorder
       Region 4gne A 1316-1413 order
 Evidence X-RAY 4gnf A Reference
       Region 4gnf A 1310-1317 disorder
       Region 4gnf A 1318-1413 order
 Evidence X-RAY 4gng A Reference
       Region 4gng A 1310-1318 disorder
       Region 4gng A 1319-1413 order
 Evidence X-RAY 4gng D Reference
       Region 4gng D 1310-1316 disorder
       Region 4gng D 1317-1413 order
SeqProS predicted 593-605 The unbound state of this region is predicted to be disordered by DICHOT and FoldIndex. Hetero dimer : IID00111Complex
       Region 2nd1 B 593-605 order
Seqphosphorylation
    150-150 Phosphoserine
    457-457 Phosphoserine
    585-585 Phosphoserine
    587-587 Phosphoserine
    590-590 Phosphoserine
    655-655 Phosphoserine
Seqacetylation
    790-790 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-263,367-703,803-914,954-956,1065-1068,1285-1315,1414-1437
Known Domain 264-366,704-802,915-953,957-1064,1069-1284,1316-1413
SCOPe RPS-Blast
     1h3zA 263-359 7e-21 b.34.9.2 DNA methyltransferase DNMT3B
     2puyA1 917-953 2e-08 g.50.1.0 automated matches
     4rxjA 957-1064 9e-43 b.34.9.2 DNA methyltransferase DNMT3B
     3bo5A 1069-1284 4e-46 b.85.7.0 automated matches
     1fp0A1 1320-1367 1e-11 g.50.1.2 Death associated transcription facto...
SCOP Hmmer
     1khcA_ 261-420 4.2e-29 b.34.9.2 DNA methyltrans...
     1wevA_ 698-756 1e-10 FYVE/PHD zinc finger
     1fp0A1 750-806 5.7e-05 g.50.1.2 Death associate...
     1wevA_ 916-967 1.8e-11 FYVE/PHD zinc finger
     1khcA_ 950-1078 3.3e-34 b.34.9.2 DNA methyltran...
     1mvhA_ 1063-1275 3.5e-73 b.85.7.1 Dim-5
     1weuA_ 1298-1366 4e-14 FYVE/PHD zinc finger
Pfam RPS-Blast
     PF00855 268-358 8e-11 PWWP domain
     PF00628 704-746 6e-04 PHD-finger
     PF00628 917-953 8e-06 PHD-finger
     PF00855 963-1046 5e-08 PWWP domain
     PF17907 1104-1142 2e-11 AWS domain
     PF00856 1156-1262 7e-06 SET domain
     PF00628 1323-1371 2e-05 PHD-finger
     PF17982 1364-1411 2e-18 NSD Cys-His rich domain
Pfam Hmmer
    PF00855 268-379 1.1e-24 PWWP domain
    PF00855 960-1048 1.1e-22 PWWP domain
    PF17907 1104-1142 2.5e-20 AWS domain
    PF00856 1156-1262 1.5e-23 SET domain
    PF17982 1364-1413 5.2e-30 NSD Cys-His rich domain