Search Keyword:


Search option:


IID00502  NAD-dependent protein deacylase sirtuin-5, mitochondrial (Homo sapiens) Q9NXA8
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
310
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 33-302 Monomer :
 Evidence X-RAY 2b4y A This region binds to ADP-ribose. Reference
       Region 2b4y A 34-35 disorder
       Region 2b4y A 36-67 order
       Region 2b4y A 68-74 disorder
       Region 2b4y A 75-302 order
 Evidence X-RAY 2b4y B This region binds to ADP-ribose. Reference
       Region 2b4y B 34-35 disorder
       Region 2b4y B 36-69 order
       Region 2b4y B 70-74 disorder
       Region 2b4y B 75-302 order
 Evidence X-RAY 2b4y C This region binds to ADP-ribose. Reference
       Region 2b4y C 34-35 disorder
       Region 2b4y C 36-71 order
       Region 2b4y C 72-75 disorder
       Region 2b4y C 76-302 order
 Evidence X-RAY 2b4y D This region binds to ADP-ribose. Reference
       Region 2b4y D 34-35 disorder
       Region 2b4y D 36-70 order
       Region 2b4y D 71-75 disorder
       Region 2b4y D 76-302 order
 Evidence X-RAY 5bwl A Reference
       Region 5bwl A 33-35 disorder
       Region 5bwl A 36-302 order
 Evidence X-RAY 6eqs A Reference
       Region 6eqs A 34-302 order
 Evidence X-RAY 6eqs B Reference
       Region 6eqs B 34-34 disorder
       Region 6eqs B 35-302 order
 Evidence X-RAY 6eqs C Reference
       Region 6eqs C 34-302 order
 Evidence X-RAY 6eqs D Reference
       Region 6eqs D 34-302 order
 Evidence X-RAY 4g1c A This region binds to inhibitor (Carba) and substrate (IDH2). Reference
       Region 4g1c A 36-302 order
 Evidence X-RAY 4g1c B This region binds to inhibitor (Carba) and substrate (IDH2). Reference
       Region 4g1c B 36-302 order
Seq 34-302 Hetero dimer : IID00062Complex
 Evidence X-RAY 4f4u A Reference
       Region 4f4u A 34-70 order
       Region 4f4u A 71-74 disorder
       Region 4f4u A 75-302 order
 Evidence X-RAY 4f4u B Reference
       Region 4f4u B 34-63 order
       Region 4f4u B 64-74 disorder
       Region 4f4u B 75-302 order
 Evidence X-RAY 4f56 A Reference
       Region 4f56 A 34-35 disorder
       Region 4f56 A 36-302 order
 Evidence X-RAY 4f56 B Reference
       Region 4f56 B 34-302 order
 Evidence X-RAY 3rig A Reference
       Region 3rig A 34-61 order
       Region 3rig A 62-73 disorder
       Region 3rig A 74-302 order
 Evidence X-RAY 3rig B Reference
       Region 3rig B 34-59 order
       Region 3rig B 60-72 disorder
       Region 3rig B 73-302 order
 Evidence X-RAY 3riy A Reference
       Region 3riy A 34-302 order
 Evidence X-RAY 3riy B Reference
       Region 3riy B 34-302 order
Seq 34-302 Homo dimer :
 Evidence X-RAY 2nyr A This region binds to inhibitor (suramin). Reference
       Region 2nyr A 34-35 disorder
       Region 2nyr A 36-277 order
       Region 2nyr A 278-285 disorder
       Region 2nyr A 286-302 order
 Evidence X-RAY 2nyr B This region binds to inhibitor (suramin). Reference
       Region 2nyr B 34-35 disorder
       Region 2nyr B 36-276 order
       Region 2nyr B 277-285 disorder
       Region 2nyr B 286-302 order
 Evidence X-RAY 4hda A This region binds to activator (resveratrol) and substrate (fluor-peptide). Reference
       Region 4hda A 34-34 disorder
       Region 4hda A 35-301 order
       Region 4hda A 302-302 disorder
 Evidence X-RAY 4hda B This region binds to activator (resveratrol) and substrate (fluor-peptide). Reference
       Region 4hda B 34-302 order
 
Prediction
DICHOT
Disorder 1-37,303-310
Known Domain 38-302
SCOPe RPS-Blast
     6eo0A1 32-301 e-120 c.31.1.5 AF0112, Sir2 homolog (Sir2-AF2)
SCOP Hmmer
     2nyrA1 38-299 3.3e-84 DHS-like NAD/FAD-binding...
Pfam RPS-Blast
     PF02146 58-169 1e-05 Sir2 family
Pfam Hmmer
    PF02146 58-256 2.4e-51 Sir2 family