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IID00525  Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens) O14920
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
756
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2-669 Homo dimer :
 Evidence X-RAY 4e3c A Reference
       Region 4e3c A 11-15 disorder
       Region 4e3c A 16-286 order
       Region 4e3c A 287-289 disorder
       Region 4e3c A 290-373 order
       Region 4e3c A 374-382 disorder
       Region 4e3c A 383-394 order
       Region 4e3c A 395-400 disorder
       Region 4e3c A 401-550 order
       Region 4e3c A 551-558 disorder
       Region 4e3c A 559-665 order
       Region 4e3c A 666-669 disorder
 Evidence X-RAY 4e3c F Reference
       Region 4e3c F 11-15 disorder
       Region 4e3c F 16-286 order
       Region 4e3c F 287-289 disorder
       Region 4e3c F 290-373 order
       Region 4e3c F 374-382 disorder
       Region 4e3c F 383-394 order
       Region 4e3c F 395-400 disorder
       Region 4e3c F 401-550 order
       Region 4e3c F 551-558 disorder
       Region 4e3c F 559-665 order
       Region 4e3c F 666-669 disorder
 Evidence X-RAY 4e3c B Reference
       Region 4e3c B 11-15 disorder
       Region 4e3c B 16-286 order
       Region 4e3c B 287-289 disorder
       Region 4e3c B 290-373 order
       Region 4e3c B 374-382 disorder
       Region 4e3c B 383-394 order
       Region 4e3c B 395-400 disorder
       Region 4e3c B 401-665 order
       Region 4e3c B 666-669 disorder
 Evidence X-RAY 4e3c C Reference
       Region 4e3c C 11-15 disorder
       Region 4e3c C 16-286 order
       Region 4e3c C 287-289 disorder
       Region 4e3c C 290-373 order
       Region 4e3c C 374-382 disorder
       Region 4e3c C 383-394 order
       Region 4e3c C 395-400 disorder
       Region 4e3c C 401-550 order
       Region 4e3c C 551-558 disorder
       Region 4e3c C 559-665 order
       Region 4e3c C 666-669 disorder
 Evidence X-RAY 4e3c D Reference
       Region 4e3c D 11-15 disorder
       Region 4e3c D 16-286 order
       Region 4e3c D 287-289 disorder
       Region 4e3c D 290-373 order
       Region 4e3c D 374-382 disorder
       Region 4e3c D 383-394 order
       Region 4e3c D 395-400 disorder
       Region 4e3c D 401-550 order
       Region 4e3c D 551-558 disorder
       Region 4e3c D 559-665 order
       Region 4e3c D 666-669 disorder
 Evidence X-RAY 4e3c E Reference
       Region 4e3c E 11-15 disorder
       Region 4e3c E 16-286 order
       Region 4e3c E 287-289 disorder
       Region 4e3c E 290-373 order
       Region 4e3c E 374-382 disorder
       Region 4e3c E 383-394 order
       Region 4e3c E 395-400 disorder
       Region 4e3c E 401-550 order
       Region 4e3c E 551-558 disorder
       Region 4e3c E 559-665 order
       Region 4e3c E 666-669 disorder
 Evidence X-RAY 4kik A Reference
       Region 4kik A 2-8 disorder
       Region 4kik A 9-23 order
       Region 4kik A 24-26 disorder
       Region 4kik A 27-84 order
       Region 4kik A 85-88 disorder
       Region 4kik A 89-169 order
       Region 4kik A 170-179 disorder
       Region 4kik A 180-372 order
       Region 4kik A 373-375 disorder
       Region 4kik A 376-400 order
       Region 4kik A 401-403 disorder
       Region 4kik A 404-501 order
       Region 4kik A 502-507 disorder
       Region 4kik A 508-550 order
       Region 4kik A 551-557 disorder
       Region 4kik A 558-663 order
       Region 4kik A 664-664 disorder
 Evidence X-RAY 4kik B Reference
       Region 4kik B 2-173 order
       Region 4kik B 174-176 disorder
       Region 4kik B 177-372 order
       Region 4kik B 373-375 disorder
       Region 4kik B 376-550 order
       Region 4kik B 551-557 disorder
       Region 4kik B 558-663 order
       Region 4kik B 664-664 disorder
Seq 701-730 Hetero trimer : IID00526Complex,Q9Y6K9
 Evidence X-RAY 3brt C Reference
       Region 3brt C 701-730 order
Seq 701-730 Hetero trimer : IID00526Complex,Q9Y6K9
 Evidence X-RAY 3brt C Reference
       Region 3brt C 701-730 order
Seq 701-730 Hetero trimer : IID00526Complex,Q9Y6K9
 Evidence X-RAY 3brt A Reference
       Region 3brt A 701-704 disorder
       Region 3brt A 705-730 order
Seq 701-730 Hetero trimer : IID00526Complex,Q9Y6K9
 Evidence X-RAY 3brt A Reference
       Region 3brt A 701-704 disorder
       Region 3brt A 705-730 order
Seq 701-745 Hetero tetramer : Q9Y6K9
 Evidence X-RAY 3brv A Reference
       Region 3brv A 701-704 disorder
       Region 3brv A 705-743 order
       Region 3brv A 744-745 disorder
 Evidence X-RAY 3brv C Reference
       Region 3brv C 701-701 disorder
       Region 3brv C 702-743 order
       Region 3brv C 744-745 disorder
Seqphosphorylation
    177-177 Phosphoserine; by TBK1 and PKC/PRKCZ
    181-181 Phosphoserine; by TBK1
    670-670 Phosphoserine; by autocatalysis
    672-672 Phosphoserine
    675-675 Phosphoserine
    675-675 Phosphoserine; by autocatalysis
    682-682 Phosphoserine; by autocatalysis
    689-689 Phosphoserine; by autocatalysis
    692-692 Phosphoserine; by autocatalysis
    695-695 Phosphoserine; by autocatalysis
    697-697 Phosphoserine; by autocatalysis
    705-705 Phosphoserine; by autocatalysis
    733-733 Phosphoserine; by autocatalysis
    740-740 Phosphoserine; by autocatalysis
    750-750 Phosphoserine; by autocatalysis
Seqacetylation
    180-180 O-acetylthreonine; by Yersinia yopJ
 
Prediction
DICHOT
Disorder 1-8,664-756
Known Domain 9-663
SCOPe RPS-Blast
     4wnoA 9-222 5e-47 d.144.1.0 automated matches
     3pseB1 317-382 2e-06 d.15.1.1 1700011n24rik protein
SCOP Hmmer
     1h8fA_ 11-290 4.9e-68 d.144.1.7 3-phosphoinosit...
     1v5tA_ 316-384 3.5e-08 Ubiquitin-like
Pfam RPS-Blast
     PF06293 94-171 5e-04 Lipopolysaccharide kinase (K...
     PF18397 389-663 e-101 IQBAL scaffold dimerization...
     PF12179 706-742 1e-08 I-kappa-kinase-beta NEMO bi...
Pfam Hmmer
    PF00069 16-290 4.9e-57 Protein kinase domain
    PF18397 389-663 3.5e-137 IQBAL scaffold dimerizati...
    PF12179 706-742 3.9e-19 I-kappa-kinase-beta NEMO b...