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IID00534  Transforming growth factor beta-1 (Homo sapiens) P01137
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
390
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 30-390 Homo dimer :
 Evidence X-RAY 5vqp A Reference
       Region 5vqp A 30-31 disorder
       Region 5vqp A 32-68 order
       Region 5vqp A 69-70 disorder
       Region 5vqp A 71-90 order
       Region 5vqp A 91-100 disorder
       Region 5vqp A 101-271 order
       Region 5vqp A 272-279 disorder
       Region 5vqp A 280-327 order
       Region 5vqp A 328-339 disorder
       Region 5vqp A 340-342 order
       Region 5vqp A 343-347 disorder
       Region 5vqp A 348-390 order
Seq 34-390 Hetero octamer : P06756,P18564
 Evidence X-RAY 5ffo C Reference
       Region 5ffo C 34-36 disorder
       Region 5ffo C 37-89 order
       Region 5ffo C 90-100 disorder
       Region 5ffo C 101-225 order
       Region 5ffo C 226-235 disorder
       Region 5ffo C 236-269 order
       Region 5ffo C 270-278 disorder
       Region 5ffo C 279-328 order
       Region 5ffo C 329-347 disorder
       Region 5ffo C 348-390 order
 Evidence X-RAY 5ffo D Reference
       Region 5ffo D 34-35 disorder
       Region 5ffo D 36-91 order
       Region 5ffo D 92-98 disorder
       Region 5ffo D 99-226 order
       Region 5ffo D 227-230 disorder
       Region 5ffo D 231-269 order
       Region 5ffo D 270-284 disorder
       Region 5ffo D 285-332 order
       Region 5ffo D 333-338 disorder
       Region 5ffo D 339-370 order
       Region 5ffo D 371-371 disorder
       Region 5ffo D 372-390 order
 Evidence X-RAY 5ffo G Reference
       Region 5ffo G 34-38 disorder
       Region 5ffo G 39-64 order
       Region 5ffo G 65-66 disorder
       Region 5ffo G 67-89 order
       Region 5ffo G 90-100 disorder
       Region 5ffo G 101-225 order
       Region 5ffo G 226-234 disorder
       Region 5ffo G 235-269 order
       Region 5ffo G 270-278 disorder
       Region 5ffo G 279-328 order
       Region 5ffo G 329-352 disorder
       Region 5ffo G 353-390 order
 Evidence X-RAY 5ffo H Reference
       Region 5ffo H 34-90 order
       Region 5ffo H 91-98 disorder
       Region 5ffo H 99-269 order
       Region 5ffo H 270-287 disorder
       Region 5ffo H 288-333 order
       Region 5ffo H 334-338 disorder
       Region 5ffo H 339-370 order
       Region 5ffo H 371-371 disorder
       Region 5ffo H 372-390 order
Seq 279-390 Homo dimer :
 Evidence NMR 1kla A Reference
       Region 1kla A 279-285 order
       Region 1kla A 286-292 disorder
       Region 1kla A 293-306 order
       Region 1kla A 307-317 disorder
       Region 1kla A 318-345 order
       Region 1kla A 346-353 disorder
       Region 1kla A 354-364 order
       Region 1kla A 365-380 disorder
       Region 1kla A 381-390 order
 Evidence NMR 1kla B Reference
       Region 1kla B 279-285 order
       Region 1kla B 286-292 disorder
       Region 1kla B 293-306 order
       Region 1kla B 307-317 disorder
       Region 1kla B 318-345 order
       Region 1kla B 346-353 disorder
       Region 1kla B 354-364 order
       Region 1kla B 365-380 disorder
       Region 1kla B 381-390 order
 Evidence NMR 1klc A Reference
       Region 1klc A 279-285 order
       Region 1klc A 286-292 disorder
       Region 1klc A 293-306 order
       Region 1klc A 307-317 disorder
       Region 1klc A 318-345 order
       Region 1klc A 346-353 disorder
       Region 1klc A 354-364 order
       Region 1klc A 365-380 disorder
       Region 1klc A 381-390 order
 Evidence NMR 1klc B Reference
       Region 1klc B 279-285 order
       Region 1klc B 286-292 disorder
       Region 1klc B 293-306 order
       Region 1klc B 307-317 disorder
       Region 1klc B 318-345 order
       Region 1klc B 346-353 disorder
       Region 1klc B 354-364 order
       Region 1klc B 365-380 disorder
       Region 1klc B 381-390 order
 Evidence NMR 1kld A Reference
       Region 1kld A 279-285 order
       Region 1kld A 286-292 disorder
       Region 1kld A 293-306 order
       Region 1kld A 307-317 disorder
       Region 1kld A 318-345 order
       Region 1kld A 346-353 disorder
       Region 1kld A 354-364 order
       Region 1kld A 365-380 disorder
       Region 1kld A 371-374 high_rmsd
       Region 1kld A 381-390 order
 Evidence NMR 1kld B Reference
       Region 1kld B 279-285 order
       Region 1kld B 286-292 disorder
       Region 1kld B 293-306 order
       Region 1kld B 307-317 disorder
       Region 1kld B 318-345 order
       Region 1kld B 346-353 disorder
       Region 1kld B 354-364 order
       Region 1kld B 365-380 disorder
       Region 1kld B 371-374 high_rmsd
       Region 1kld B 381-390 order
 Evidence X-RAY 4kv5 C Reference
       Region 4kv5 C 279-390 order
 Evidence X-RAY 4kv5 D Reference
       Region 4kv5 D 279-390 order
 Evidence X-RAY 4kv5 A Reference
       Region 4kv5 A 279-390 order
 Evidence X-RAY 4kv5 B Reference
       Region 4kv5 B 279-390 order
Seq 279-390 Hetero hexamer : IID00413Complex,IID00414Complex
 Evidence X-RAY 3kfd A Reference
       Region 3kfd A 279-390 order
 Evidence X-RAY 3kfd B Reference
       Region 3kfd B 279-390 order
 Evidence X-RAY 3kfd C Reference
       Region 3kfd C 279-390 order
 Evidence X-RAY 3kfd D Reference
       Region 3kfd D 279-390 order
SeqProS verified 286-292 Hetero hexamer : IID00413Complex,IID00414Complex
       Region 3kfd A 279-390 order
       Region 3kfd B 279-390 order
       Region 3kfd C 279-390 order
       Region 3kfd D 279-390 order
       Region 1kld A 286-292 disorder
 
Prediction
DICHOT
Disorder 1-29
Known Domain 30-390
SCOPe RPS-Blast
     1tgjA 279-390 8e-50 g.17.1.2 Activin A (Inhibin beta A)
SCOP Hmmer
     2tgiA_ 281-389 9.3e-37 g.17.1.2 Activin A (Inhi...
Pfam RPS-Blast
     PF00688 31-231 6e-18 TGF-beta propeptide
     PF00019 292-389 3e-13 Transforming growth factor ...
Pfam Hmmer
    PF00688 31-259 6e-44 TGF-beta propeptide
    PF00019 292-389 2.9e-26 Transforming growth factor...