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IID00566  Growth factor receptor-bound protein 7 (Homo sapiens) Q14451
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
532
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 100-186 Monomer :
 Evidence NMR 1wgr A Reference
       Region 1wgr A 100-186 order
       Region 1wgr A 134-139 high_rmsd
Seq 415-532 Hetero dimer : IID00293Complex
 Evidence NMR 2l4k A Reference
       Region 2l4k A 415-532 order
       Region 2l4k A 415-429 high_rmsd
       Region 2l4k A 532-532 high_rmsd
 Evidence NMR 1mw4 A Reference
       Region 1mw4 A 415-532 order
       Region 1mw4 A 415-418 high_rmsd
Seq 415-532 Hetero dimer :
 Evidence X-RAY 5eeq B Reference
       Region 5eeq B 415-423 disorder
       Region 5eeq B 424-527 order
       Region 5eeq B 528-532 disorder
Seq 415-532 Hetero trimer :
 Evidence X-RAY 5d0j A Reference
       Region 5d0j A 415-425 disorder
       Region 5d0j A 426-531 order
       Region 5d0j A 532-532 disorder
 Evidence X-RAY 5d0j B Reference
       Region 5d0j B 415-421 disorder
       Region 5d0j B 422-486 order
       Region 5d0j B 487-487 disorder
       Region 5d0j B 488-529 order
       Region 5d0j B 530-532 disorder
Seq 415-532 Hetero tetramer :
 Evidence X-RAY 5u1q A Reference
       Region 5u1q A 415-428 disorder
       Region 5u1q A 429-528 order
       Region 5u1q A 529-532 disorder
 Evidence X-RAY 5u1q B Reference
       Region 5u1q B 415-421 disorder
       Region 5u1q B 422-528 order
       Region 5u1q B 529-532 disorder
Seq 415-532 Hetero trimer :
 Evidence X-RAY 5d0j C Reference
       Region 5d0j C 415-428 disorder
       Region 5d0j C 429-530 order
       Region 5d0j C 531-532 disorder
 Evidence X-RAY 5d0j D Reference
       Region 5d0j D 415-423 disorder
       Region 5d0j D 424-488 order
       Region 5d0j D 489-489 disorder
       Region 5d0j D 490-528 order
       Region 5d0j D 529-532 disorder
Seq 415-532 Homo dimer :
 Evidence X-RAY 2qms A Reference
       Region 2qms A 415-419 disorder
       Region 2qms A 420-532 order
 Evidence X-RAY 2qms B Reference
       Region 2qms B 415-419 disorder
       Region 2qms B 420-532 order
 Evidence X-RAY 2qms C Reference
       Region 2qms C 415-419 disorder
       Region 2qms C 420-532 order
 Evidence X-RAY 2qms D Reference
       Region 2qms D 415-419 disorder
       Region 2qms D 420-532 order
 Evidence X-RAY 5tyi A Reference
       Region 5tyi A 415-424 disorder
       Region 5tyi A 425-486 order
       Region 5tyi A 487-487 disorder
       Region 5tyi A 488-529 order
       Region 5tyi A 530-532 disorder
 Evidence X-RAY 5tyi B Reference
       Region 5tyi B 415-422 disorder
       Region 5tyi B 423-487 order
       Region 5tyi B 488-489 disorder
       Region 5tyi B 490-529 order
       Region 5tyi B 530-532 disorder
 Evidence X-RAY 5tyi C Reference
       Region 5tyi C 415-425 disorder
       Region 5tyi C 426-485 order
       Region 5tyi C 486-486 disorder
       Region 5tyi C 487-530 order
       Region 5tyi C 531-532 disorder
 Evidence X-RAY 5tyi D Reference
       Region 5tyi D 415-424 disorder
       Region 5tyi D 425-487 order
       Region 5tyi D 488-488 disorder
       Region 5tyi D 489-527 order
       Region 5tyi D 528-532 disorder
 Evidence X-RAY 5u06 A Reference
       Region 5u06 A 415-425 disorder
       Region 5u06 A 426-532 order
 Evidence X-RAY 5u06 B Reference
       Region 5u06 B 415-426 disorder
       Region 5u06 B 427-528 order
       Region 5u06 B 529-532 disorder
 Evidence X-RAY 5u06 C Reference
       Region 5u06 C 415-422 disorder
       Region 5u06 C 423-530 order
       Region 5u06 C 531-532 disorder
 Evidence X-RAY 5u06 D Reference
       Region 5u06 D 415-424 disorder
       Region 5u06 D 425-487 order
       Region 5u06 D 488-489 disorder
       Region 5u06 D 490-529 order
       Region 5u06 D 530-532 disorder
 Evidence X-RAY 4wwq A Reference
       Region 4wwq A 415-420 disorder
       Region 4wwq A 421-532 order
 Evidence X-RAY 4wwq B Reference
       Region 4wwq B 415-532 order
Seq 415-532 Hetero tetramer :
 Evidence X-RAY 5u1q C Reference
       Region 5u1q C 415-422 disorder
       Region 5u1q C 423-487 order
       Region 5u1q C 488-488 disorder
       Region 5u1q C 489-528 order
       Region 5u1q C 529-532 disorder
 Evidence X-RAY 5u1q D Reference
       Region 5u1q D 415-428 disorder
       Region 5u1q D 429-529 order
       Region 5u1q D 530-532 disorder
Seq 415-532 Monomer :
 Evidence X-RAY 5eel A Reference
       Region 5eel A 415-425 disorder
       Region 5eel A 426-529 order
       Region 5eel A 530-532 disorder
 Evidence X-RAY 5eel B Reference
       Region 5eel B 415-420 disorder
       Region 5eel B 421-529 order
       Region 5eel B 530-532 disorder
 Evidence X-RAY 5eel C Reference
       Region 5eel C 415-426 disorder
       Region 5eel C 427-532 order
 Evidence X-RAY 5eel D Reference
       Region 5eel D 415-427 disorder
       Region 5eel D 428-529 order
       Region 5eel D 530-532 disorder
 Evidence X-RAY 5eel E Reference
       Region 5eel E 415-428 disorder
       Region 5eel E 429-530 order
       Region 5eel E 531-532 disorder
 Evidence X-RAY 5eel F Reference
       Region 5eel F 415-426 disorder
       Region 5eel F 427-530 order
       Region 5eel F 531-532 disorder
Seq 415-532 Hetero dimer :
 Evidence X-RAY 5eeq A Reference
       Region 5eeq A 415-425 disorder
       Region 5eeq A 426-528 order
       Region 5eeq A 529-532 disorder
Seq 416-532 Hetero trimer :
 Evidence X-RAY 3pqz B Reference
       Region 3pqz B 416-422 disorder
       Region 3pqz B 423-463 order
       Region 3pqz B 464-464 disorder
       Region 3pqz B 465-487 order
       Region 3pqz B 488-488 disorder
       Region 3pqz B 489-529 order
       Region 3pqz B 530-532 disorder
 Evidence X-RAY 3pqz C Reference
       Region 3pqz C 416-429 disorder
       Region 3pqz C 430-488 order
       Region 3pqz C 489-489 disorder
       Region 3pqz C 490-527 order
       Region 3pqz C 528-532 disorder
Seq 416-532 Hetero trimer :
 Evidence X-RAY 3pqz A Reference
       Region 3pqz A 416-423 disorder
       Region 3pqz A 424-462 order
       Region 3pqz A 463-463 disorder
       Region 3pqz A 464-528 order
       Region 3pqz A 529-532 disorder
 Evidence X-RAY 3pqz D Reference
       Region 3pqz D 416-428 disorder
       Region 3pqz D 429-487 order
       Region 3pqz D 488-489 disorder
       Region 3pqz D 490-527 order
       Region 3pqz D 528-532 disorder
Seq 423-529 Hetero dimer :
 Evidence X-RAY 4x6s B Reference
       Region 4x6s B 423-529 order
Seq 423-529 Hetero dimer :
 Evidence X-RAY 4x6s A Reference
       Region 4x6s A 423-423 disorder
       Region 4x6s A 424-529 order
Seqphosphorylation
    188-188 Phosphotyrosine; by FAK1
    338-338 Phosphotyrosine; by FAK1
    361-361 Phosphoserine
 
Prediction
DICHOT
Disorder 1-103,348-419
Known Domain 104-347,420-532
SCOPe RPS-Blast
     1wgrA1 100-186 3e-27 d.15.1.5 A-Raf proto-oncogene serine/threonine...
     1v89A1 230-334 2e-07 b.55.1.1 3-phosphoinositide dependent protein ...
     1nrvA 425-529 3e-44 d.93.1.1 Abl tyrosine kinase
SCOP Hmmer
     1wgrA_ 96-192 3.9e-34 Ubiquitin-like
     1fgyA_ 230-343 3.8e-17 b.55.1.1 3-phosphoinosit...
     1mw4A_ 418-529 3.1e-32 SH2 domain
Pfam RPS-Blast
     PF00788 101-184 6e-09 Ras association (RalGDS/AF-...
     PF08947 365-411 6e-16 BPS (Between PH and SH2)
     PF00017 431-512 5e-05 SH2 domain
Pfam Hmmer
    PF00788 101-184 5e-18 Ras association (RalGDS/AF-6...
    PF00169 231-334 2.7e-12 PH domain
    PF08947 365-412 2.3e-31 BPS (Between PH and SH2)
    PF00017 431-512 9.6e-20 SH2 domain