IDEAL Node

IDEAL

IID00568 Mediator of DNA damage checkpoint protein 1 (Homo sapiens) Q14676

:order :disorder :conflict :PDB cluster :ProS :SCOP Domain :Pfam Domain

Network xml

Experiment

2089

fasta

order/disorder by at least rule

disorder by at least rule

order by at least rule

order/disorder by majority rule

Seq 1-10,19-138 Hetero dimer :

Evidence X-RAY 3uot E Reference

Region 3uot E 1-1 disorder

Region 3uot E 2-9 order

Region 3uot E 10-10 disorder

Evidence X-RAY 3uot D Reference

Region 3uot D 1-1 disorder

Region 3uot D 2-9 order

Region 3uot D 10-10 disorder

Evidence X-RAY 3unn B Reference

Region 3unn B 1-8 order

Evidence X-RAY 3uot B Reference

Region 3uot B 19-27 disorder

Region 3uot B 28-134 order

Region 3uot B 135-138 disorder

Evidence X-RAY 3uot A Reference

Region 3uot A 19-135 order

Region 3uot A 136-138 disorder

Evidence X-RAY 3unn A Reference

Region 3unn A 27-133 order

Region 3unn A 134-138 disorder

Seq 26-138 Homo dimer :

Evidence X-RAY 3unm B Reference

Region 3unm B 27-28 disorder

Region 3unm B 29-134 order

Region 3unm B 135-138 disorder

Evidence X-RAY 3unm A Reference

Region 3unm A 27-28 disorder

Region 3unm A 29-101 order

Region 3unm A 102-104 disorder

Region 3unm A 105-109 order

Region 3unm A 110-110 disorder

Region 3unm A 111-133 order

Region 3unm A 134-138 disorder

Evidence X-RAY 3un0 B Reference

Region 3un0 B 26-26 disorder

Region 3un0 B 27-133 order

Region 3un0 B 134-138 disorder

Evidence X-RAY 3un0 A Reference

Region 3un0 A 26-134 order

Region 3un0 A 135-138 disorder

Evidence X-RAY 3umz B Reference

Region 3umz B 27-28 disorder

Region 3umz B 29-133 order

Region 3umz B 134-138 disorder

Evidence X-RAY 3umz A Reference

Region 3umz A 27-28 disorder

Region 3umz A 29-133 order

Region 3umz A 134-138 disorder

Seq 325-336 Hetero trimer : Q92547

Evidence X-RAY 3ueo E Reference

Region 3ueo E 325-325 disorder

Region 3ueo E 326-335 order

Region 3ueo E 336-336 disorder

Evidence X-RAY 3ueo F Reference

Region 3ueo F 325-327 disorder

Region 3ueo F 328-335 order

Region 3ueo F 336-336 disorder

Seq 1883-2089 Hetero dimer : IID00027Complex

Evidence X-RAY 2azm B Reference

Region 2azm B 1883-1890 disorder

Region 2azm B 1891-2085 order

Region 2azm B 2086-2089 disorder

Evidence X-RAY 2azm A Reference

Region 2azm A 1883-1890 disorder

Region 2azm A 1891-2083 order

Region 2azm A 2084-2089 disorder

Seq 1884-2089 Homo dimer :

Evidence X-RAY 2etx B Reference

Region 2etx B 1884-1890 disorder

Region 2etx B 1891-2085 order

Region 2etx B 2086-2089 disorder

Evidence X-RAY 2etx A Reference

Region 2etx A 1884-1891 disorder

Region 2etx A 1892-2085 order

Region 2etx A 2086-2089 disorder

Seq 1891-2089 Monomer :

Evidence X-RAY 3k05 B

This region binds to a peptide. Reference

Region 3k05 B 1891-2089 order

Evidence X-RAY 3k05 A

This region binds to a peptide. Reference

Region 3k05 A 1891-2083 order

Region 3k05 A 2084-2089 disorder

Evidence X-RAY 2ado B Reference

Region 2ado B 1891-2085 order

Region 2ado B 2086-2086 disorder

Evidence X-RAY 2ado A Reference

Region 2ado A 1891-1891 disorder

Region 2ado A 1892-2085 order

Region 2ado A 2086-2086 disorder

Seqphosphorylation

1858-1858 Phosphothreonine

1820-1820 Phosphoserine

1800-1800 Phosphothreonine

1711-1711 Phosphoserine

1775-1775 Phosphoserine

1702-1702 Phosphoserine

1681-1681 Phosphoserine

1697-1697 Phosphothreonine

1671-1671 Phosphothreonine

1604-1604 Phosphoserine

1608-1608 Phosphothreonine

1630-1630 Phosphothreonine

1664-1664 Phosphothreonine

1548-1548 Phosphothreonine

1564-1564 Phosphoserine

1567-1567 Phosphothreonine

1589-1589 Phosphothreonine

1425-1425 Phosphothreonine

1466-1466 Phosphothreonine

1399-1399 Phosphoserine

1400-1400 Phosphoserine

1403-1403 Phosphothreonine

1280-1280 Phosphothreonine

1302-1302 Phosphothreonine

1198-1198 Phosphothreonine

1235-1235 Phosphoserine

1239-1239 Phosphothreonine

1157-1157 Phosphothreonine

1068-1068 Phosphoserine

1086-1086 Phosphoserine

1033-1033 Phosphoserine

955-955 Phosphoserine

998-998 Phosphoserine

793-793 Phosphoserine

780-780 Phosphoserine

590-590 Phosphoserine

513-513 Phosphoserine

523-523 Phosphothreonine

505-505 Phosphoserine

504-504 Phosphoserine

498-498 Phosphoserine

495-495 Phosphoserine

485-485 Phosphoserine

455-455 Phosphothreonine

453-453 Phosphoserine

449-449 Phosphothreonine

404-404 Phosphothreonine

411-411 Phosphoserine

402-402 Phosphoserine

397-397 Phosphoserine

394-394 Phosphoserine

378-378 Phosphothreonine

376-376 Phosphoserine

372-372 Phosphoserine

331-331 Phosphothreonine

329-329 Phosphoserine

301-301 Phosphothreonine

299-299 Phosphoserine

176-176 Phosphoserine

146-146 Phosphothreonine

168-168 Phosphoserine

108-108 Phosphoserine

4-4 Phosphothreonine; by ATM

1858-1858 Phosphothreonine

1820-1820 Phosphoserine

1800-1800 Phosphothreonine

1775-1775 Phosphoserine

1702-1702 Phosphoserine

1711-1711 Phosphoserine

1697-1697 Phosphothreonine

1671-1671 Phosphothreonine

1681-1681 Phosphoserine

1664-1664 Phosphothreonine

1630-1630 Phosphothreonine

1608-1608 Phosphothreonine

1604-1604 Phosphoserine

1589-1589 Phosphothreonine

1567-1567 Phosphothreonine

1564-1564 Phosphoserine

1548-1548 Phosphothreonine

1466-1466 Phosphothreonine

1425-1425 Phosphothreonine

1403-1403 Phosphothreonine

1400-1400 Phosphoserine

1399-1399 Phosphoserine

1302-1302 Phosphothreonine

1280-1280 Phosphothreonine

1239-1239 Phosphothreonine

1235-1235 Phosphoserine

1198-1198 Phosphothreonine

1157-1157 Phosphothreonine

1086-1086 Phosphoserine

1033-1033 Phosphoserine

1068-1068 Phosphoserine

998-998 Phosphoserine

955-955 Phosphoserine

793-793 Phosphoserine

590-590 Phosphoserine

780-780 Phosphoserine

513-513 Phosphoserine

523-523 Phosphothreonine

504-504 Phosphoserine

505-505 Phosphoserine

498-498 Phosphoserine

495-495 Phosphoserine

455-455 Phosphothreonine

485-485 Phosphoserine

453-453 Phosphoserine

411-411 Phosphoserine

449-449 Phosphothreonine

404-404 Phosphothreonine

394-394 Phosphoserine

397-397 Phosphoserine

402-402 Phosphoserine

376-376 Phosphoserine

378-378 Phosphothreonine

372-372 Phosphoserine

329-329 Phosphoserine

331-331 Phosphothreonine

299-299 Phosphoserine

301-301 Phosphothreonine

168-168 Phosphoserine

176-176 Phosphoserine

146-146 Phosphothreonine

108-108 Phosphoserine

4-4 Phosphothreonine; by ATM

Seqacetylation

1402-1402 N6-acetyllysine

812-812 N6-acetyllysine

1402-1402 N6-acetyllysine

812-812 N6-acetyllysine

Prediction

DICHOT

Disorder 1-28,134-1099,1191-1373,1479-1891,2086-2089

Known Domain 29-133,1100-1190,1374-1478,1892-2085

SCOPe RPS-Blast

2affA 30-110 2e-11

1kzyC1 1856-1968 1e-14

SCOP Hmmer

1uhtA_ 28-134 7.6e-19 SMAD/FHA domain

1kzyC1 1897-1987 3.5e-21

1jnxX2 1994-2074 1.6e-06

Pfam RPS-Blast

PF16697 35-110 4e-09 Inner membrane component of ...

PF05110 1043-1790 1e-06 AF-4 proto-oncoprotein

PF16770 1877-1969 4e-20 Regulator of Ty1 transpos...

Pfam Hmmer

PF00498 55-123 3.2e-14 FHA domain

PF16770 1883-1968 2.2e-10 Regulator of Ty1 transpo...