Search Keyword:


Search option:


IID50007  Nucleoporin NUP2 (Saccharomyces cerevisiae (strain ATCC 204508 / S288c)) P32499
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
720
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-51 Hetero dimer : IID50012Complex
 Evidence X-RAY 1un0 C Reference
       Region 1un0 C 1-35 disorder
       Region 1un0 C 36-51 order
 Evidence X-RAY 1un0 D Reference
       Region 1un0 D 1-35 disorder
       Region 1un0 D 36-51 order
Seq 1-51 Hetero dimer : IID50012Complex
 Evidence X-RAY 2c1t C Reference
       Region 2c1t C 1-1 disorder
       Region 2c1t C 2-18 order
       Region 2c1t C 19-27 disorder
       Region 2c1t C 28-46 order
       Region 2c1t C 47-51 disorder
 Evidence X-RAY 2c1t D Reference
       Region 2c1t D 1-1 disorder
       Region 2c1t D 2-18 order
       Region 2c1t D 19-24 disorder
       Region 2c1t D 25-46 order
       Region 2c1t D 47-51 disorder
Seqdisorder 1-720
 Evidence CD¸FTIR spectroscopy¸protease sensitivity¸ gel filtration¸ sedimentation velocity Reference
       Region 1-720 disorder
SeqProS verified 2-18,25-46 These regions bind to Kap60 (yeast importin alpha) competing with NLS Hetero dimer : IID50012Complex
       Region 2c1t C 2-18 order
       Region 2c1t C 28-46 order
       Region 2c1t D 2-18 order
       Region 2c1t D 25-46 order
       Region 1-720 disorder
SeqProS verified 36-51 This region binds to Kap60 (yeast importin alpha) competing with NLS Hetero dimer : IID50012Complex
       Region 1un0 C 36-51 order
       Region 1un0 D 36-51 order
       Region 1-720 disorder
Seqphosphorylation
    17-17 Phosphoserine
    20-20 Phosphoserine
    137-137 Phosphoserine
    165-165 Phosphoserine
    203-203 Phosphoserine
    205-205 Phosphoserine
    348-348 Phosphoserine
    351-351 Phosphoserine
    361-361 Phosphothreonine
    581-581 Phosphoserine
    590-590 Phosphothreonine
 
Prediction
DICHOT
Disorder 1-605,718-720
Known Domain 606-717
SCOPe RPS-Blast
     4gmxB 602-720 7e-24 b.55.1.0 automated matches
SCOP Hmmer
     1rrpB_ 592-717 4e-34 b.55.1.3 Nuclear pore comp...
Pfam RPS-Blast
     PF00638 602-714 4e-10 RanBP1 domain
Pfam Hmmer
    PF08911 2-71 7e-18 NUP50 (Nucleoporin 50 kDa)
    PF00638 598-718 5.6e-48 RanBP1 domain