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IID50008  CREB-binding protein (Mus musculus) P45481
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
2441
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 1-127
 Evidence NMR Reference
       Region 1-127 disorder
Seq 340-439 Hetero dimer : Q04207
 Evidence NMR 2lww A Reference
       Region 2lww A 340-439 order
       Region 2lww A 340-344 high_rmsd
       Region 2lww A 438-439 high_rmsd
Seq 340-439 Monomer :
 Evidence NMR 1u2n A Reference
       Region 1u2n A 340-439 order
       Region 1u2n A 340-344 high_rmsd
       Region 1u2n A 376-376 high_rmsd
       Region 1u2n A 437-439 high_rmsd
Seq 340-439 Hetero dimer : IID00053Complex
 Evidence NMR 2ka4 A Reference
       Region 2ka4 A 340-439 order
       Region 2ka4 A 340-341 high_rmsd
       Region 2ka4 A 377-377 high_rmsd
       Region 2ka4 A 438-439 high_rmsd
Seq 340-439 Hetero dimer : IID00015Complex
 Evidence NMR 5hou A Reference
       Region 5hou A 340-439 order
       Region 5hou A 340-343 high_rmsd
Seq 340-439 Hetero dimer : IID00179Complex
 Evidence NMR 1r8u B Reference
       Region 1r8u B 340-439 order
       Region 1r8u B 340-343 high_rmsd
       Region 1r8u B 374-377 high_rmsd
Seq 345-439 Hetero dimer : IID00085Complex
 Evidence NMR 1l8c A Reference
       Region 1l8c A 345-439 order
       Region 1l8c A 375-377 high_rmsd
       Region 1l8c A 436-439 high_rmsd
Seq 586-666 Hetero dimer : IID50004Complex
 Evidence NMR 1kdx A Reference
       Region 1kdx A 586-666 order
       Region 1kdx A 586-586 high_rmsd
       Region 1kdx A 666-666 high_rmsd
Seq 586-672 Hetero dimer : IID00433Complex
 Evidence NMR 2lqh A Reference
       Region 2lqh A 586-672 order
       Region 2lqh A 586-586 high_rmsd
 Evidence NMR 2lqi A Reference
       Region 2lqi A 586-672 order
       Region 2lqi A 586-586 high_rmsd
Seq 586-672 Hetero dimer : P06876
 Evidence NMR 1sb0 A Reference
       Region 1sb0 A 586-672 order
Seq 586-672 Monomer :
 Evidence X-RAY 4i9o A Reference
       Region 4i9o A 586-587 disorder
       Region 4i9o A 588-665 order
       Region 4i9o A 666-672 disorder
Seq 586-672 Hetero dimer : IID00207Complex
 Evidence NMR 5u4k A Reference
       Region 5u4k A 586-672 order
       Region 5u4k A 586-586 high_rmsd
       Region 5u4k A 671-672 high_rmsd
Seq 586-672 Hetero trimer : IID00379Complex,P06876
 Evidence NMR 2agh B Reference
       Region 2agh B 586-672 order
       Region 2agh B 586-588 high_rmsd
       Region 2agh B 671-672 high_rmsd
Seq 1079-1556 Monomer :
 Evidence X-RAY 5u7g A Reference
       Region 5u7g A 1079-1210 order
       Region 5u7g A 1211-1272 disorder
       Region 5u7g A 1273-1556 order
 Evidence X-RAY 5u7g B Reference
       Region 5u7g B 1079-1210 order
       Region 5u7g B 1211-1272 disorder
       Region 5u7g B 1273-1556 order
Seq 1083-1198 Monomer :
 Evidence X-RAY 5w0i A Reference
       Region 5w0i A 1083-1084 disorder
       Region 5w0i A 1085-1198 order
Seq 1700-1751 Monomer :
 Evidence NMR 1tot A Reference
       Region 1tot A 1700-1751 order
Seq 1764-1850 Monomer :
 Evidence NMR 1f81 A Reference
       Region 1f81 A 1764-1850 order
Seq 1764-1855 Hetero dimer : IID00015Complex
 Evidence NMR 5hpd A Reference
       Region 5hpd A 1764-1855 order
Seq 1764-1855 Hetero dimer : IID00046Complex
 Evidence NMR 2ka6 A Reference
       Region 2ka6 A 1764-1855 order
       Region 2ka6 A 1855-1855 high_rmsd
Seq 1764-1857 Hetero dimer : IID00015Complex
 Evidence NMR 5hp0 A Reference
       Region 5hp0 A 1764-1857 order
       Region 5hp0 A 1857-1857 high_rmsd
Seqdisorder 2057-2117
 Evidence NMR Reference
       Region 2057-2117 disorder
Seq 2059-2117 Hetero dimer : IID00083Complex
 Evidence NMR 2c52 A Reference
       Region 2c52 A 2059-2116 order
       Region 2c52 A 2059-2060 high_rmsd
       Region 2c52 A 2116-2116 high_rmsd
       Region 2c52 A 2117-2117 disorder
Seq 2059-2117 Monomer :
 Evidence NMR 1jjs A Reference
       Region 1jjs A 2067-2082 order
       Region 1jjs A 2082-2082 high_rmsd
       Region 1jjs A 2083-2086 disorder
       Region 1jjs A 2087-2112 order
 Evidence NMR 2kkj A Reference
       Region 2kkj A 2059-2117 order
       Region 2kkj A 2059-2061 high_rmsd
       Region 2kkj A 2107-2117 high_rmsd
Seq 2059-2117 Hetero dimer : IID00015Complex
 Evidence NMR 2l14 A Reference
       Region 2l14 A 2059-2117 order
       Region 2l14 A 2059-2061 high_rmsd
       Region 2l14 A 2111-2117 high_rmsd
Seq 2059-2117 Hetero dimer : IID00110Complex
 Evidence NMR 1kbh B Reference
       Region 1kbh B 2059-2117 order
       Region 1kbh B 2115-2117 high_rmsd
SeqProS verified 2059-2116 Hetero dimer : IID00083Complex
       Region 2c52 A 2059-2116 order
       Region 2057-2117 disorder
SeqProS verified 2059-2117 Hetero dimer : IID00110Complex
       Region 1kbh B 2059-2117 order
       Region 2057-2117 disorder
SeqProS verified 2059-2117 Hetero dimer : IID00015Complex
       Region 2l14 A 2059-2117 order
       Region 2057-2117 disorder
Seqphosphorylation
    120-120 Phosphoserine
    1031-1031 Phosphoserine
    1077-1077 Phosphoserine
    1383-1383 Phosphoserine; by IKKA
    1387-1387 Phosphoserine; by IKKA
    1764-1764 Phosphoserine
    2064-2064 Phosphoserine
    2077-2077 Phosphoserine
    2080-2080 Phosphoserine
    2350-2350 Phosphoserine
Seqacetylation
    2-2 N-acetylalanine
    656-656 N6-acetyllysine
    1015-1015 N6-acetyllysine
    1217-1217 N6-acetyllysine
    1584-1584 N6-acetyllysine
    1592-1592 N6-acetyllysine
    1593-1593 N6-acetyllysine
    1596-1596 N6-acetyllysine
    1598-1598 N6-acetyllysine
    1742-1742 N6-acetyllysine
    1745-1745 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-344,440-587,780-1082,1551-1604,1752-1761,1847-2065,2113-2441
Known Domain 345-439,588-779,1083-1550,1605-1751,1762-1846,2066-2112
SCOPe RPS-Blast
     1l8cA 345-439 4e-39 g.53.1.1 CREB-binding transcriptional adaptor pr...
     4i9oA 588-665 9e-35 a.12.1.1 Kix domain of CBP (creb binding protei...
     4nyxA 1083-1198 2e-62 a.29.2.1 CREB-binding protein, CBP
     2n1aB 1700-1752 5e-27 g.44.1.6 CREB-binding protein, CBP
     1f81A 1764-1850 5e-38 g.53.1.1 CREB-binding transcriptional adaptor ...
     1zoqC 2066-2112 1e-12 a.153.1.1 Nuclear receptor coactivator 1, NCO...
SCOP Hmmer
     1l3eB_ 343-437 1.9e-30 g.53.1.1 CREB-binding tr...
     1sb0A_ 588-671 1e-38 a.12.1.1 Kix domain of CBP...
     1eqfA1 1072-1198 6.9e-38 a.29.2.1 CREB-binding ...
     1totA1 1701-1748 2.3e-15 g.44.1.6 CREB-binding ...
     1f81A_ 1765-1849 4.5e-26 g.53.1.1 CREB-binding ...
     1kbhB_ 2060-2116 6.3e-29 a.153.1.1 Nuclear rece...
Pfam RPS-Blast
     PF15967 75-323 3e-05 Nucleoporin FG repeated regi...
     PF02135 354-435 9e-18 TAZ zinc finger
     PF02172 589-625 4e-09 KIX domain
     PF03154 675-1025 2e-10 Atrophin-1 family
     PF00439 1095-1177 3e-12 Bromodomain
     PF06001 1193-1232 5e-19 Domain of Unknown Functio...
     PF08214 1360-1596 5e-54 Histone acetylation prote...
     PF00569 1706-1743 1e-08 Zinc finger, ZZ type
     PF02135 1774-1853 6e-27 TAZ zinc finger
     PF12851 1879-2275 2e-07 Oxygenase domain of the 2...
Pfam Hmmer
    PF02135 353-429 3.1e-22 TAZ zinc finger
    PF02172 587-666 3.2e-42 KIX domain
    PF00439 1105-1178 9.4e-20 Bromodomain
    PF06001 1193-1232 1.7e-25 Domain of Unknown Functi...
    PF08214 1343-1648 2.9e-66 Histone acetylation prot...
    PF00569 1703-1743 5.9e-19 Zinc finger, ZZ type
    PF02135 1773-1844 2.2e-15 TAZ zinc finger
    PF09030 2021-2114 4e-38 Creb binding