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IID50012  Importin subunit alpha (Saccharomyces cerevisiae (strain ATCC 204508 / S288c)) Q02821
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
542
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-530 Hetero trimer : IID50075Complex,IID50081Complex
 Evidence X-RAY 1wa5 B Reference
       Region 1wa5 B 1-11 disorder
       Region 1wa5 B 12-19 order
       Region 1wa5 B 20-30 disorder
       Region 1wa5 B 31-58 order
       Region 1wa5 B 59-86 disorder
       Region 1wa5 B 87-513 order
       Region 1wa5 B 514-530 disorder
Seq 1-542 Hetero dimer : P21827
 Evidence X-RAY 5t94 B Reference
       Region 5t94 B 1-87 disorder
       Region 5t94 B 88-509 order
       Region 5t94 B 510-542 disorder
Seq 87-509 Hetero trimer : IID00012Complex
 Evidence X-RAY 1ee4 A Reference
       Region 1ee4 A 87-509 order
 Evidence X-RAY 1ee4 B Reference
       Region 1ee4 B 87-509 order
Seq 87-510 Hetero dimer : IID50001Complex
 Evidence X-RAY 1ee5 A Reference
       Region 1ee5 A 87-89 disorder
       Region 1ee5 A 90-510 order
Seq 88-509 Hetero dimer : IID50288Complex
 Evidence X-RAY 4pvz A Reference
       Region 4pvz A 88-509 order
Seq 88-509 Hetero dimer : IID50288Complex
 Evidence X-RAY 4pvz B Reference
       Region 4pvz B 88-509 order
Seq 88-509 Hetero dimer : Q03707
 Evidence X-RAY 4xzr B Reference
       Region 4xzr B 88-509 order
Seq 88-510 Hetero dimer : Q02724
 Evidence X-RAY 5h2w A Reference
       Region 5h2w A 88-88 disorder
       Region 5h2w A 89-465 order
       Region 5h2w A 466-470 disorder
       Region 5h2w A 471-509 order
       Region 5h2w A 510-510 disorder
 Evidence X-RAY 5h2w C Reference
       Region 5h2w C 88-88 disorder
       Region 5h2w C 89-463 order
       Region 5h2w C 464-470 disorder
       Region 5h2w C 471-509 order
       Region 5h2w C 510-510 disorder
 Evidence X-RAY 5h2x A Reference
       Region 5h2x A 88-465 order
       Region 5h2x A 466-470 disorder
       Region 5h2x A 471-510 order
Seq 88-530 Hetero dimer : IID50007Complex
 Evidence X-RAY 1un0 A Reference
       Region 1un0 A 88-526 order
       Region 1un0 A 527-530 disorder
 Evidence X-RAY 1un0 B Reference
       Region 1un0 B 88-526 order
       Region 1un0 B 527-530 disorder
Seq 88-541 Hetero dimer : IID50007Complex
 Evidence X-RAY 2c1t A Reference
       Region 2c1t A 88-510 order
       Region 2c1t A 511-541 disorder
 Evidence X-RAY 2c1t B Reference
       Region 2c1t B 88-510 order
       Region 2c1t B 511-541 disorder
Seq 89-510 Homo dimer :
 Evidence X-RAY 1bk5 A Reference
       Region 1bk5 A 89-510 order
 Evidence X-RAY 1bk5 B Reference
       Region 1bk5 B 89-510 order
Seq 89-510 Hetero trimer :
 Evidence X-RAY 1bk6 A Reference
       Region 1bk6 A 89-510 order
Seq 89-510 Hetero trimer :
 Evidence X-RAY 1bk6 B Reference
       Region 1bk6 B 89-510 order
SeqProS possible 12-19,31-58 Same region of mouse homolog (P52293, 57%identity) is disordered in the free state Hetero trimer : IID50075Complex,IID50081Complex
       Region 1wa5 B 12-19 order
       Region 1wa5 B 31-58 order
Seqacetylation
    1-1 N-acetylmethionine
 
Prediction
DICHOT
Disorder 1-96,511-542
Known Domain 97-510
SCOPe RPS-Blast
     4b8jA 33-509 e-136 a.118.1.0 automated matches
SCOP Hmmer
     1wa5B_ 13-514 3.3e-141 a.118.1.1 beta-Catenin
Pfam RPS-Blast
     PF01749 19-107 3e-13 Importin beta binding domain
     PF04826 126-308 4e-07 Armadillo-like
     PF00514 333-368 3e-08 Armadillo/beta-catenin-like...
     PF00514 374-409 4e-08 Armadillo/beta-catenin-like...
     PF16186 471-523 7e-18 Atypical Arm repeat
Pfam Hmmer
    PF01749 17-108 5e-31 Importin beta binding domain
    PF00514 121-160 9e-15 Armadillo/beta-catenin-like ...
    PF00514 163-201 3.5e-13 Armadillo/beta-catenin-lik...
    PF00514 205-244 1.2e-12 Armadillo/beta-catenin-lik...
    PF00514 248-286 1.3e-10 Armadillo/beta-catenin-lik...
    PF00514 289-327 7e-10 Armadillo/beta-catenin-like ...
    PF00514 330-370 6.5e-16 Armadillo/beta-catenin-lik...
    PF00514 372-411 2.5e-15 Armadillo/beta-catenin-lik...
    PF00514 418-455 2.2e-09 Armadillo/beta-catenin-lik...
    PF16186 471-523 9.2e-25 Atypical Arm repeat