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IID50044  Serine/threonine-protein kinase PAK 1 (Rattus norvegicus) P35465
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
544
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 75-118
 Evidence NMR Reference
       Region 75-118 disorder
Seq 75-118 Hetero dimer : IID00308Complex
 Evidence NMR 1e0a B Reference
       Region 1e0a B 75-108 order
       Region 1e0a B 109-118 disorder
       Region 1e0a B 113-118 high_rmsd
SeqProS verified 75-108 Hetero dimer : IID00308Complex
       Region 1e0a B 75-108 order
       Region 75-118 disorder
Seqphosphorylation
    21-21 Phosphoserine; by PKB and autocatalysis
    57-57 Phosphoserine; by autocatalysis
    84-84 Phosphothreonine; by OXSR1
    115-115 Phosphoserine
    131-131 Phosphotyrosine
    142-142 Phosphotyrosine
    144-144 Phosphoserine; by autocatalysis
    149-149 Phosphoserine; by autocatalysis
    153-153 Phosphotyrosine; by JAK2
    174-174 Phosphoserine
    184-184 Phosphothreonine
    198-198 Phosphoserine; by autocatalysis
    200-200 Phosphotyrosine; by JAK2
    203-203 Phosphoserine; by autocatalysis
    211-211 Phosphothreonine
    218-218 Phosphothreonine
    219-219 Phosphoserine
    222-222 Phosphoserine
    224-224 Phosphothreonine
    228-228 Phosphothreonine
    229-229 Phosphothreonine
    284-284 Phosphotyrosine; by JAK2
    422-422 Phosphothreonine; by autocatalysis
Seqacetylation
    2-2 N-acetylserine
 
Prediction
DICHOT
Disorder 1-77,148-247,541-544
Known Domain 78-147,248-540
SCOPe RPS-Blast
     1ej5A 79-132 6e-04 a.68.1.1 Wiscott-Aldrich syndrome protein, WASP, ...
     2j0iA 248-537 e-168 d.144.1.0 automated matches
SCOP Hmmer
     2jflA1 260-521 4.2e-89 Protein kinase-like (PK...
Pfam RPS-Blast
     PF00786 76-131 6e-13 P21-Rho-binding domain
     PF06293 340-410 2e-05 Lipopolysaccharide kinase (...
     PF14531 385-452 1e-06 Kinase-like
Pfam Hmmer
    PF00786 74-132 3.2e-28 P21-Rho-binding domain
    PF00069 269-520 1.4e-76 Protein kinase domain