Search Keyword:


Search option:


IID50246  Serine/threonine-protein kinase TOR1 (Saccharomyces cerevisiae (strain ATCC 204508 / S288c)) P35169
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
xml
Experiment
2470
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2438-2470 Monomer :
 Evidence NMR 2kio A This region is oxidized DPC micelle-bound FITC domain. Upon reduction, the flexibility of this region increases and influences the affinity with DPC micelles. Reference
       Region 2kio A 2438-2470 order
       Region 2kio A 2438-2440 high_rmsd
       Region 2kio A 2468-2470 high_rmsd
 Evidence NMR 2kit A Reference
       Region 2kit A 2438-2470 order
       Region 2kit A 2438-2438 high_rmsd
 Evidence NMR 1w1n A Reference
       Region 1w1n A 2438-2470 order
       Region 1w1n A 2438-2439 high_rmsd
 
Prediction
DICHOT
Disorder 1-112,525-561
Known Domain 113-465,625-2470
Cryptic Domain 466-524,562-624
SCOPe RPS-Blast
     5o9zV 563-1160 9e-26 a.118.1.2 Constant regulatory domain of protei...
     4jspA3 1334-1938 e-138 a.24.7.1 mTOR FKBP12??apamycin-binding (FRB)...
     4driB1 1962-2049 1e-33 a.24.7.1 mTOR FKBP12??apamycin-binding (FRB)...
     4jspA1 2032-2470 0.0 d.144.1.4 mTOR kinase domain
SCOP Hmmer
     1u6gC_ 73-1450 1.3e-149 a.118.1.2 Constant regu...
     1qbkB_ 1246-1950 1.9e-07 a.118.1.1 beta-Catenin
     3fapB_ 1956-2048 5.2e-40 a.24.7.1 mTOR FKBP12??...
     1e8yA4 2029-2413 1.4e-97 d.144.1.4 mTOR kinase ...
Pfam RPS-Blast
     PF13513 227-280 6e-04 HEAT-like repeat
     PF11865 833-985 1e-37 Domain of unknown function ...
     PF02259 1461-1845 1e-42 FAT domain
     PF08771 1952-2041 1e-27 FKBP12-rapamycin binding ...
     PF00454 2119-2366 3e-09 Phosphatidylinositol 3- a...
     PF02260 2440-2470 4e-12 FATC domain
Pfam Hmmer
    PF11865 827-986 1.1e-65 Domain of unknown function...
    PF02259 1461-1845 1.6e-133 FAT domain
    PF08771 1952-2049 4.8e-45 FKBP12-rapamycin binding...
    PF00454 2119-2366 6e-76 Phosphatidylinositol 3- an...
    PF02260 2440-2470 7.6e-20 FATC domain