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IID50277  Signal transducer and activator of transcription 3 (Mus musculus) P42227
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
xml
Experiment
770
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 3-127 Homo dimer :
 Evidence X-RAY 4zia A Reference
       Region 4zia A 3-124 order
       Region 4zia A 125-127 disorder
 Evidence X-RAY 4zia B Reference
       Region 4zia B 3-124 order
       Region 4zia B 125-127 disorder
 Evidence X-RAY 4zia C Reference
       Region 4zia C 3-6 order
       Region 4zia C 7-16 disorder
       Region 4zia C 17-115 order
       Region 4zia C 116-127 disorder
 Evidence X-RAY 4zia D Reference
       Region 4zia D 3-124 order
       Region 4zia D 125-127 disorder
 Evidence X-RAY 4zia E Reference
       Region 4zia E 3-122 order
       Region 4zia E 123-127 disorder
Seq 127-688 Monomer :
 Evidence X-RAY 3cwg A Reference
       Region 3cwg A 127-135 disorder
       Region 3cwg A 136-180 order
       Region 3cwg A 181-199 disorder
       Region 3cwg A 200-370 order
       Region 3cwg A 371-378 disorder
       Region 3cwg A 379-398 order
       Region 3cwg A 399-400 disorder
       Region 3cwg A 401-418 order
       Region 3cwg A 419-430 disorder
       Region 3cwg A 431-597 order
       Region 3cwg A 598-598 disorder
       Region 3cwg A 599-623 order
       Region 3cwg A 624-630 disorder
       Region 3cwg A 631-646 order
       Region 3cwg A 647-649 disorder
       Region 3cwg A 650-688 order
 Evidence X-RAY 3cwg B Reference
       Region 3cwg B 127-135 disorder
       Region 3cwg B 136-184 order
       Region 3cwg B 185-194 disorder
       Region 3cwg B 195-370 order
       Region 3cwg B 371-378 disorder
       Region 3cwg B 379-398 order
       Region 3cwg B 399-400 disorder
       Region 3cwg B 401-418 order
       Region 3cwg B 419-430 disorder
       Region 3cwg B 431-623 order
       Region 3cwg B 624-630 disorder
       Region 3cwg B 631-646 order
       Region 3cwg B 647-649 disorder
       Region 3cwg B 650-658 order
       Region 3cwg B 659-662 disorder
       Region 3cwg B 663-688 order
Seq 127-715 Homo dimer :
 Evidence X-RAY 1bg1 A Reference
       Region 1bg1 A 127-135 disorder
       Region 1bg1 A 136-184 order
       Region 1bg1 A 185-193 disorder
       Region 1bg1 A 194-688 order
       Region 1bg1 A 689-701 disorder
       Region 1bg1 A 702-715 order
 Evidence X-RAY 4e68 A Reference
       Region 4e68 A 127-135 disorder
       Region 4e68 A 136-184 order
       Region 4e68 A 185-193 disorder
       Region 4e68 A 194-688 order
       Region 4e68 A 689-701 disorder
       Region 4e68 A 702-715 order
Seqphosphorylation
    705-705 Phosphotyrosine; by FER and PTK6
    714-714 Phosphothreonine
    727-727 Phosphoserine
    727-727 Phosphoserine; by DYRK2
Seqacetylation
    2-2 N-acetylalanine
    601-601 N6-acetyllysine; alternate
    615-615 N6-acetyllysine; alternate
    631-631 N6-acetyllysine; alternate
    685-685 N6-acetyllysine; alternate
    707-707 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-1,117-135,716-770
Known Domain 2-116,136-715
SCOPe RPS-Blast
     1bgfA 1-122 5e-37 a.90.1.1 Transcription factor STAT-4 N-domain
     1bg1A1 136-321 3e-43 a.47.1.1 STAT homologue coiled coil domain
     1bg1A2 322-575 6e-75 b.2.5.5 STAT homologue
     1bg1A3 576-715 1e-43 d.93.1.1 Abl tyrosine kinase
SCOP Hmmer
     1bgfA_ 1-120 7.2e-44 a.90.1.1 Transcription fac...
     1bg1A1 136-321 4.5e-66 a.47.1.1 STAT homologue ...
     1bg1A2 322-575 2.9e-112 b.2.5.5 STAT homologue
     1bg1A3 576-714 2.3e-45 d.93.1.1 Abl tyrosine ki...
Pfam RPS-Blast
     PF02865 2-119 3e-32 STAT protein, protein interac...
     PF01017 142-312 2e-28 STAT protein, all-alpha dom...
     PF02864 336-464 3e-28 STAT protein, DNA binding d...
Pfam Hmmer
    PF02865 2-119 1.1e-41 STAT protein, protein intera...
    PF01017 141-312 2.7e-57 STAT protein, all-alpha do...
    PF02864 326-464 2e-41 STAT protein, DNA binding do...
    PF00017 584-674 2.9e-17 SH2 domain