Order: Ordered regions are those regions in which atomically detailed 3D structures are available in PDB.

Disorder: Disordered regions in IDEAL are
1) missing residues in X-ray structural models
2) regions interfere protein crystallization in a X-ray experiment
3) regions highly fluctuate among an ensemble of model structures obtained by NMR, and their fluctuations are described explicitly in the corresponding literature.
4) regions proved to be flexible in experimental techniques such as NMR, CD, and others.

Conflict: When a region is assigned as ordered in one annotation, but the alternative annotation describes it as disordered, the region is thought to be "conflict".

Protean segment(ProS): The protean segment (ProS) is the region that is disordered in an isolated state, but ordered in a binding state with a partner molecule, via the coupled folding and binding mechanism. We defined two categories for ProS, verified ProS and possible ProS. A verified ProS is defined as the sequence, which has both evidences of disordered and of ordered. A possible ProS is defined as the sequence, which only has an evidence of ordered in a binding state, but is thought tobe a ProS from circumstantial evidences even though it has no evidence of disordered in an isolated state

SCOP Domain: SCOP is the database of Structural Classification Of Protein 3D structures. SCOP domains are assigned to proteins in IDEAL by the sensitive homology search tools, Reverse PSI-BLAST and Hmmer. Note that ordered regions assigned in the order/disorder annotation process are experimentally verified ordered regions in a query sequence itself, while the SCOP domains here are assigned employing homology searches.

Pfam Domain: Pfam is the protein family database. Pfam domains are defined based on sequence conservation, and they do not necessarily correspond to structural domains. Pfam domains are assigned by the sensitive homology search tools.

At least rule: This is a rule to summarize multiple annotations on a region. The "at least rule" assigns "order" ("disorder") to a region if the region was annotated as ordered (disordered) at least once. When the annotation is inconsistent, the region is annotated as conflict.

Majority rule: This is a rule to summarize multiple annotations on a region. The "majority rule" assigns "order" or "disorder" to a region according to the majority decision of all evidences.

IDEAL

Full Text UniProt Accession Protein Name PDB id search

ID	name	organism	length	ProS
IID00001	Nuclear receptor subfamily 5 group A member 2	Homo sapiens	541	✔
IID00002	B-cell CLL/lymphoma 9 protein	Homo sapiens	1426
IID00003	Chromodomain-helicase-DNA-binding protein 1	Homo sapiens	1710
IID00004	tRNA (cytosine-5-)-methyltransferase	Homo sapiens	391
IID00005	Protein Mdm4	Homo sapiens	490
IID00006	Phospholipid scramblase 1	Homo sapiens	318	✔
IID00007	Axin-1	Homo sapiens	862	✔
IID00008	E3 ubiquitin-protein ligase parkin	Homo sapiens	465
IID00010	Histone H2B type 1-K	Homo sapiens	126
IID00011	Steroid hormone receptor ERR2	Homo sapiens	500	✔
IID00012	Myc proto-oncogene protein	Homo sapiens	439	✔
IID00013	Estrogen receptor	Homo sapiens	595	✔
IID00014	Glucocorticoid receptor	Homo sapiens	777
IID00015	Cellular tumor antigen p53	Homo sapiens	393	✔
IID00016	Histone H2A type 1-B/E	Homo sapiens	130
IID00017	Retinoblastoma-associated protein	Homo sapiens	928	✔
IID00018	U1 small nuclear ribonucleoprotein A	Homo sapiens	282
IID00019	Histone H2A.Z	Homo sapiens	128
IID00020	Androgen receptor	Homo sapiens	919
IID00021	Steroid hormone receptor ERR1	Homo sapiens	423
IID00022	Proliferating cell nuclear antigen	Homo sapiens	261
IID00023	ATP-dependent DNA helicase 2 subunit 1	Homo sapiens	609
IID00024	ATP-dependent DNA helicase 2 subunit 2	Homo sapiens	732
IID00025	Protein C-ets-1	Homo sapiens	441
IID00026	Replication protein A 32 kDa subunit	Homo sapiens	270
IID00027	Histone H2A.x	Homo sapiens	143
IID00028	Histone H1.5	Homo sapiens	226	✔
IID00029	Galectin-3	Homo sapiens	250
IID00030	Negative elongation factor E	Homo sapiens	380	✔
IID00031	Retinoic acid receptor RXR-alpha	Homo sapiens	462
IID00032	Cyclin-A2	Homo sapiens	432
IID00033	Nuclear receptor subfamily 1 group D member 1	Homo sapiens	614
IID00034	Cell division protein kinase 2	Homo sapiens	298
IID00035	Adenomatous polyposis coli protein	Homo sapiens	2843	✔
IID00036	Replication protein A 70 kDa DNA-binding subunit	Homo sapiens	616
IID00037	RAC-beta serine/threonine-protein kinase	Homo sapiens	481	✔
IID00038	14-3-3 protein beta/alpha	Homo sapiens	246
IID00039	Catenin beta-1	Homo sapiens	781	✔
IID00040	Replication protein A 14 kDa subunit	Homo sapiens	121
IID00041	Peroxisome proliferator-activated receptor gamma	Homo sapiens	505
IID00042	Breast cancer type 1 susceptibility protein	Homo sapiens	1863
IID00043	Cyclin-dependent kinase inhibitor 1	Homo sapiens	164	✔
IID00044	Flap endonuclease 1	Homo sapiens	380	✔
IID00045	Hepatocyte nuclear factor 4-alpha	Homo sapiens	474
IID00046	Signal transducer and activator of transcription 1-alpha/beta	Homo sapiens	750	✔
IID00047	Signal transducer and activator of transcription 6	Homo sapiens	847	✔
IID00048	DNA mismatch repair protein Msh2	Homo sapiens	934
IID00049	Cyclin-dependent kinase inhibitor 1B	Homo sapiens	198	✔
IID00050	Nuclear receptor-interacting protein 1	Homo sapiens	1158	✔
IID00051	DNA polymerase delta subunit 2	Homo sapiens	469
IID00052	Glycogen synthase kinase-3 beta	Homo sapiens	420	✔
IID00053	Signal transducer and activator of transcription 2	Homo sapiens	851	✔
IID00054	DNA mismatch repair protein Msh6	Homo sapiens	1360
IID00056	Calmodulin	Homo sapiens	149
IID00057	Estrogen-related receptor gamma	Homo sapiens	458
IID00058	Histone H4	Homo sapiens	103	✔
IID00059	RING-box protein 1	Homo sapiens	108
IID00060	Calcineurin subunit B type 1	Homo sapiens	170
IID00061	14-3-3 protein zeta/delta	Homo sapiens	245
IID00062	Histone H3.1	Homo sapiens	136	✔
IID00063	FK506-binding protein 3	Homo sapiens	224
IID00064	Transcription factor E2F1	Homo sapiens	437	✔
IID00065	Forkhead box protein K2	Homo sapiens	660
IID00066	Protein kinase C epsilon type	Homo sapiens	737	✔
IID00067	Paired box protein Pax-5	Homo sapiens	391
IID00068	FK506-binding protein 4	Homo sapiens	459
IID00069	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Homo sapiens	521	✔
IID00070	Histone acetyltransferase p300	Homo sapiens	2414
IID00071	Nucleosome-remodeling factor subunit BPTF	Homo sapiens	3046
IID00072	Steroidogenic factor 1	Homo sapiens	461
IID00073	FK506-binding protein 5	Homo sapiens	457
IID00074	Nuclear receptor coactivator 4	Homo sapiens	614	✔
IID00075	Heterogeneous nuclear ribonucleoprotein D0	Homo sapiens	355	✔
IID00076	Transcription factor Dp-1	Homo sapiens	410
IID00077	Hepatocyte nuclear factor 4-gamma	Homo sapiens	408
IID00078	Meiotic recombination protein DMC1/LIM15 homolog	Homo sapiens	340
IID00079	Interferon regulatory factor 3	Homo sapiens	427
IID00080	DNA polymerase delta subunit 3	Homo sapiens	466	✔
IID00081	Nuclear receptor subfamily 0 group B member 2	Homo sapiens	257	✔
IID00082	Nuclear receptor coactivator 2	Homo sapiens	1464	✔
IID00083	Nuclear receptor coactivator 1	Homo sapiens	1441	✔
IID00084	Histone-binding protein RBBP7	Homo sapiens	425
IID00085	Hypoxia-inducible factor 1 alpha	Homo sapiens	826	✔
IID00086	Histone H3.1t	Homo sapiens	136	✔
IID00087	BCL-6 corepressor	Homo sapiens	1755
IID00088	Histone H3.2	Homo sapiens	136	✔
IID00089	Cullin-associated NEDD8-dissociated protein 1	Homo sapiens	1230
IID00090	Protein SMG7	Homo sapiens	1137
IID00091	Estrogen receptor beta	Homo sapiens	530
IID00092	CREB-binding protein	Homo sapiens	2442	✔
IID00093	Proto-oncogene FRAT1	Homo sapiens	279	✔
IID00094	Transportin-1	Homo sapiens	898
IID00095	Lethal(3)malignant brain tumor-like 2 protein	Homo sapiens	705
IID00096	Crossover junction endonuclease EME1	Homo sapiens	570
IID00097	E3 ubiquitin-protein ligase CHFR	Homo sapiens	664
IID00098	Crossover junction endonuclease MUS81	Homo sapiens	551
IID00099	Cell division control protein 6 homolog	Homo sapiens	560
IID00100	Transcription factor 7-like 2	Homo sapiens	619	✔
IID00101	Histone-lysine N-methyltransferase SETD8	Homo sapiens	393
IID00102	Beta-catenin-interacting protein 1	Homo sapiens	81	✔
IID00103	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	Homo sapiens	798	✔
IID00104	SUMO-activating enzyme subunit 2	Homo sapiens	640
IID00105	DNA polymerase kappa	Homo sapiens	870	✔
IID00106	DNA polymerase iota	Homo sapiens	715
IID00107	Protein SMG5	Homo sapiens	1016
IID00108	DNA polymerase eta	Homo sapiens	713
IID00109	Nuclear receptor corepressor 2	Homo sapiens	2525	✔
IID00111	Bromodomain-containing protein 4	Homo sapiens	1362
IID00112	Zinc finger FYVE domain-containing protein 9	Homo sapiens	1425	✔
IID00113	Mothers against decapentaplegic homolog 3	Homo sapiens	425	✔
IID00114	E3 ubiquitin-protein ligase NEDD4-like	Homo sapiens	975
IID00115	Snurportin-1	Homo sapiens	360	✔
IID00116	DNA cross-link repair 1B protein	Homo sapiens	532
IID00117	RNA polymerase II subunit A C-terminal domain phosphatase	Homo sapiens	961	✔
IID00118	E3 ubiquitin-protein ligase RNF8	Homo sapiens	485
IID00119	Heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	372	✔
IID00120	E3 ubiquitin-protein ligase SIAH1	Homo sapiens	282
IID00121	Upstream stimulatory factor 1	Homo sapiens	310	✔
IID00122	F-actin-capping protein subunit alpha-1	Homo sapiens	286	✔
IID00123	Tumor suppressor p53-binding protein 1	Homo sapiens	1972
IID00124	Apoptosis-stimulating of p53 protein 2	Homo sapiens	1128
IID00125	Calcyclin-binding protein	Homo sapiens	228	✔
IID00126	DNA-directed RNA polymerase II subunit RPB1	Homo sapiens	1970	✔
IID00127	Mothers against decapentaplegic homolog 2	Homo sapiens	467	✔
IID00128	Histone-lysine N-methyltransferase SETD7	Homo sapiens	366
IID00129	Alpha-actinin-4	Homo sapiens	911
IID00130	Retinoblastoma-like protein 1	Homo sapiens	1068	✔
IID00131	Ski oncogene	Homo sapiens	728
IID00132	Mothers against decapentaplegic homolog 4	Homo sapiens	552
IID00133	Cullin-1	Homo sapiens	776
IID00134	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	Homo sapiens	358	✔
IID00135	Mothers against decapentaplegic homolog 7	Homo sapiens	426	✔
IID00136	E3 SUMO-protein ligase PIAS2	Homo sapiens	621
IID00137	Annexin A1	Homo sapiens	346	✔
IID00138	U1 small nuclear ribonucleoprotein 70 kDa	Homo sapiens	437
IID00139	U1 small nuclear ribonucleoprotein C	Homo sapiens	159
IID00140	Serum response factor	Homo sapiens	508
IID00141	G2/mitotic-specific cyclin-B1	Homo sapiens	433
IID00142	Homeobox protein Hox-B1	Homo sapiens	301
IID00143	Small nuclear ribonucleoprotein-associated proteins B and B'	Homo sapiens	240
IID00144	POU domain, class 2, transcription factor 1	Homo sapiens	743
IID00145	High mobility group protein HMG-I/HMG-Y	Homo sapiens	107	✔
IID00146	ETS domain-containing protein Elk-1	Homo sapiens	428	✔
IID00147	Splicing factor U2AF 65 kDa subunit	Homo sapiens	475
IID00148	ETS domain-containing protein Elk-4	Homo sapiens	431	✔
IID00149	Pre-B-cell leukemia transcription factor 1	Homo sapiens	430
IID00150	Butyrate response factor 2	Homo sapiens	494
IID00151	E3 SUMO-protein ligase RanBP2	Homo sapiens	3224	✔
IID00152	Heterogeneous nuclear ribonucleoprotein M	Homo sapiens	730	✔
IID00153	Importin subunit alpha-2	Homo sapiens	529	✔
IID00154	Protein HIRA	Homo sapiens	1017	✔
IID00155	Telomeric repeat-binding factor 1	Homo sapiens	439	✔
IID00156	Small nuclear ribonucleoprotein E	Homo sapiens	92
IID00157	Small nuclear ribonucleoprotein F	Homo sapiens	86
IID00158	Small nuclear ribonucleoprotein G	Homo sapiens	76
IID00159	Small nuclear ribonucleoprotein Sm D1	Homo sapiens	119
IID00160	Small nuclear ribonucleoprotein Sm D2	Homo sapiens	118
IID00161	Small nuclear ribonucleoprotein Sm D3	Homo sapiens	126
IID00162	GTP-binding nuclear protein Ran	Homo sapiens	216	✔
IID00163	E3 ubiquitin-protein ligase Mdm2	Homo sapiens	491	✔
IID00164	DNA repair protein complementing XP-C cells	Homo sapiens	940
IID00165	MAD protein	Homo sapiens	221	✔
IID00166	Elongation factor 1-alpha 2	Homo sapiens	463
IID00167	Nuclear cap-binding protein subunit 1	Homo sapiens	790	✔
IID00168	Serine/threonine-protein kinase 4	Homo sapiens	487
IID00169	RE1-silencing transcription factor	Homo sapiens	1097	✔
IID00170	Eukaryotic translation initiation factor 4E-binding protein 1	Homo sapiens	118	✔
IID00171	Transcription factor E2F2	Homo sapiens	437	✔
IID00172	Serine/threonine-protein kinase 38	Homo sapiens	465	✔
IID00173	Mediator of RNA polymerase II transcription subunit 1	Homo sapiens	1581	✔
IID00174	Mothers against decapentaplegic homolog 1	Homo sapiens	465	✔
IID00175	POU domain class 2-associating factor 1	Homo sapiens	256	✔
IID00176	Ubiquitin carboxyl-terminal hydrolase 7	Homo sapiens	1102
IID00177	PRKC apoptosis WT1 regulator protein	Homo sapiens	340	✔
IID00178	E3 ubiquitin-protein ligase Itchy homolog	Homo sapiens	903
IID00179	Cbp/p300-interacting transactivator 2	Homo sapiens	270	✔
IID00180	TERF1-interacting nuclear factor 2	Homo sapiens	451
IID00181	Fanconi anemia group J protein	Homo sapiens	1249
IID00182	Histone chaperone ASF1A	Homo sapiens	204
IID00183	Calcineurin-binding protein cabin-1	Homo sapiens	2220
IID50001	Nucleoplasmin	Xenopus laevis	200	✔
IID50002	Histone-binding protein N1/N2	Xenopus laevis	590	✔
IID50003	Cadherin-1	Mus musculus	884	✔
IID50004	Cyclic AMP-responsive element-binding protein 1	Rattus norvegicus	341	✔
IID50005	Protein C-ets-1	Mus musculus	440	✔
IID50006	Lymphoid enhancer-binding factor 1	Mus musculus	397	✔
IID50007	Nucleoporin NUP2	Saccharomyces cerevisiae	720	✔
IID50008	CREB-binding protein	Mus musculus	2441	✔
IID50009	Importin subunit alpha-2	Mus musculus	529	✔
IID50010	Transcription factor 7-like 1-A	Xenopus laevis	554	✔
IID50011	Catenin beta-1	Mus musculus	781	✔
IID50012	Importin subunit alpha	Saccharomyces cerevisiae	542	✔
IID50013	Serotonin N-acetyltransferase	Ovis aries	207	✔
IID50014	B-catenin	Danio rerio	780
IID50015	Tax1-binding protein 3	Mus musculus	124
IID50016	Nucleoporin 50 kDa	Mus musculus	466	✔
IID50017	Axin-1	Xenopus laevis	842	✔
IID50018	Tegument protein VP16	Human herpesvirus 1 (strain F)	490	✔
IID50019	Protein S100-B	Rattus norvegicus	92
IID50020	Tegument protein VP16	Human herpesvirus 1 (strain 17)	490	✔
IID50021	RNA polymerase II transcription factor B subunit 1	Saccharomyces cerevisiae	642
IID50022	Protein S100-B	Bos taurus	92
IID50023	Homeobox protein Hox-A9	Mus musculus	271
IID50024	Nuclear factor erythroid 2-related factor 2	Mus musculus	597	✔
IID50025	Histone deacetylase 9	Mus musculus	588
IID90001	NAD-dependent deacetylase 2	Archaeoglobus fulgidus	253
IID90002	Large T antigen	Simian virus 40	708	✔
IID90003	Early E1A 32 kDa protein	Human adenovirus C serotype 5	289	✔
IID90004	Epstein-Barr nuclear antigen 1	Epstein-Barr virus (strain B95-8)	641	✔