20210801 20180803 20180228 20210801 IID00074 Nuclear receptor coactivator 4 Androgen receptor coactivator 70 kDa protein Androgen receptor-associated protein of 70 kDa Ret-activating protein ELE1 Homo sapiens 614 Q13772 A8K8W5 B4E260 E9PAV7 J3KQN8 Q14239 Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. 328 332 0 0 MNTFQDQSGSSSNREPLLRCSDARRDLELAIGGVLRAEQQIKDNLREVKAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQAQQLYSLLGQFNCLTHQLECTQNKDLANQVSVCLERLGSLTLKPEDSTVLLFEADTITLRQTITTFGSLKTIQIPEHLMAHASSANIGPFLEKRGCISMPEQKSASGIVAVPFSEWLLGSKPASGYQAPYIPSTDPQDWLTQKQTLENSQTSSRACNFFNNVGGNLKGLENWLLKSEKSSYQKCNSHSTTSSFSIEMEKVGDQELPDQDEMDLSDWLVTPQESHKLRKPENGSRETSEKFKLLFQSYNVNDWLVKTDSCTNCQGNQPKGVEIENLGNLKCLNDHLEAKKPLSTPSMVTEDWLVQNHQDPCKVEEVCRANEPCTSFAECVCDENCEKEALYKWLLKKEGKDKNGMPVEPKPEPEKHKDSLNMWLCPRKEVIEQTKAPKAMTPSRIADSFQVIKNSPLSEWLIRPPYKEGSPKEVPGTEDRAGKQKFKSPMNTSWCSFNTADWVLPGKKMGNLSQLSSGEDKWLLRKKAQEVLLNSPLQEEHNFPPDHYGLPAVCDLFACMQLKVDKEKWLYRTPLQM 1 1t5zB 322 324 disorder 1 2 1t5zB 325 335 order 1 3 1t5zB 336 336 disorder 1 1 1t5z X-RAY 298K 7.5 15563469 E.ESTEBANEZ-PERPINA,J.M.R.MOORE,E.MAR,E.DELGADO-RODRIGUES,P.NGUYEN,J.D.BAXTER,B.M.BUEHRER,P.WEBB,R.J.FLETTERICK,R.K.GUY 2005 J.BIOL.CHEM. 280 8060 x-ray 1t5z B 322 336 100 2 322 324 336 336 1 1t5z_1 3077 Hetero dimer 1t5zB Q13772 IID00074 1t5zA P10275 IID00020 1t5zB-1t5zA ProS 1 possible 2 325 335 FXXLF motif 1-19,78-99,163-175,229-385,437-558 20-77,100-162,176-228,386-436,559-614 213 PF12489 35->165 3.3e-30 Nuclear coactivator hmm pfm 214 PF12489 199->321 3.4e-51 Nuclear coactivator hmm pfm 5478 PF12489 39->165 1e-11 Nuclear coactivator rps pfm 5479 PF12489 206->318 3e-22 Nuclear coactivator rps pfm