20210801 20180803 20180328 20210801 IID00573 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B G1 to S phase transition protein 2 homolog Homo sapiens 628 Q8IYD1 Q9H909 Q9NVY0 Q9NY44 Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Cytoplasm. SL-0086 unkown 0 0 0 0 MDSGSSSSDSAPDCWDQVDMESPGSAPSGDGVSSAVAEAQREPLSSAFSRKLNVNAKPFVPNVHAAEFVPSFLRGPTQPPTLPAGSGSNDETCTGAGYPQGKRMGRGAPVEPSREEPLVSLEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEPGGGSSGDSGPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD 1 3kujB 59 73 order 1 1 3kuj X-RAY 295K 4 20418951 G.KOZLOV,K.GEHRING 2010 PLOS ONE 5 E1016 x-ray 3kuj B 59 73 100 0 1 3kuj_1 2463 Hetero dimer 3kujA P11940 IID00193 3kujB Q8IYD1 IID00573 3kujA-3kujB 198-625 1-197,626-628 1654 PF00009 201->400 2.4e-49 Elongation factor Tu GTP binding domain hmm pfm 1655 PF03143 520->623 1.8e-34 Elongation factor Tu C-terminal domain hmm pfm 1656 PF03144 443->510 7.9e-11 Elongation factor Tu domain 2 hmm pfm 1657 PF07145 47->64 6.7e-09 Ataxin-2 C-terminal region hmm pfm 4242 1f60A3 199->443 4.6e-65 hmm scp 4243 1f60A2 521->624 3.3e-32 hmm scp 4244 1r5bA1 425->515 1.3e-22 hmm scp 6758 PF03144 443->510 5e-07 Elongation factor Tu domain 2 rps pfm 9135 1zunB3 200->421 2e-90 rps scp 9136 1r5bA1 422->516 7e-26 rps scp 9137 1f60A2 521->622 4e-25 rps scp